Results 51 to 60 of about 8,720 (195)
Scientific Reports, 2017 Chronic cerebral hypoperfusion is a major cause of age-related vascular cognitive impairment. A well-characterised mouse model has shown that hypoperfusion results in gliovascular and white matter damage and impaired spatial working memory. In this study,
Akihiro Kitamura +12 more
doaj +1 more source
ATP Release and Purinergic Signaling Potentiate β‐Adrenergic Effects on Brown Adipocytes
Acta Physiologica, Volume 242, Issue 10, October 2026.ABSTRACT Aim Brown adipose tissue (BAT) specializes in energy consumption and thermogenesis in response to cold stress. Brown adipocytes (BA) express purinergic receptors, yet little is known about the source of extracellular ATP and the role of purinergic signaling, and the potential interaction with β‐adrenergic signaling.
Marco Tozzi +8 more
wiley +1 more source
Russian Open Medical Journal, 2013 Cilostazol is a phosphodiesterase III inhibitor, which was approved by FDA (food and drug administration) for intermittent claudication in 1999. What made it known to cardiologists is the Cilostazol for Restenosis Trial (CREST), in which cilostazol was ...
Lihua Zhong +3 more
doaj
BMC Cardiovascular Disorders, 2018 Background Cilostazol has been associated with spontaneous reports of cardiovascular adverse events and serious bleeding. The objective of this study is to determine the relative risk of cardiovascular adverse events or haemorrhages in patients with ...
Jordi Real +9 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 17, 14 September 2026.Computational studies allowed the identification of a PDE9A inhibitor. A novel HPLC‐based assay was developed and optimized to measure enzyme function to assess PDE9A inhibition. Furthermore, in vitro tests supported the activity of the compound against neuroinflammation. Oxidative stress and inflammation are key players in central nervous system (CNS)
Giovanni Ribaudo +10 more
wiley +1 more source
EFFECTS OF ROSUVASTATIN IN EXPERIMENTALLY-INDUCED CARDIAC ISCHEMIA AND ON AORTIC VASCULAR REACTIVITY. [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2017 Myocardial infarction (MI) continues to be a major public health problem in the world. The present study aimed to elucidate the protective effect of different doses of rosuvastatin and cilostazol, as well as their combination on isoprenaline-induced MI
Maryam Hamouda
doaj +1 more source
Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 801-815, September 1, 2026.ABSTRACT Background The European Society of Cardiology (ESC) guidelines for peripheral artery disease recommend antithrombotic strategies based on high ischemic risk (HIR) and high bleeding risk (HBR) criteria. However, their prognostic value in patients with lower extremity artery disease (LEAD) undergoing endovascular therapy (EVT) remains unclear ...
Hirokazu Shimono +8 more
wiley +1 more source
, 2020 A dolgozatban a cilostazol polimorfiáját vizsgáltam és a polimorf módosulatok pordiffrakciós vizsgálatával foglalkoztam. A hatóanyag polimorf módosulatainak meghatározása mellett kokristály képzést kíséreltem meg.
Szőke, László
core
Effects of cilostazol administration on the fertility of female mice.
, 2012 (A) treated with cilostazol, (B) treatment with cilostazol stopped. The value of the litter size is not a percentage, but numerical data. In image (A), Black solid rectangle represents cilostazol treatment group, and black hollow rectangle represents ...
Yue Zhao (186573) +8 more
core +1 more source
Spectrophotometric Determination of Cilostazol in Tablet Dosage Form [PDF]
, 2010 Purpose: To develop simple, rapid and selective spectrophotometric methods for the determination of cilostazol in tablet dosage form. Methods: Cilostazol was dissolved in 50 % methanol and its absorbance was scanned by ultraviolet (UV) spectrophotometry.
Kumar, V +3 more
core +1 more source