Results 41 to 50 of about 8,720 (195)
Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases
Phytotherapy Research, EarlyView.Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin +7 more
wiley +1 more source
Einfluss von Cilostazol auf die Frakturheilung im murinen Ischämiemodell [PDF]
, 2020 Eine ausreichende Vaskularisierung und Angiogenese sind entscheidende Faktoren für eine erfolgreiche Frakturheilung. Es konnte in verschiedenen Studien gezeigt werden, dass Cilostazol, ein selektiver Inhibitor der Phosphodiesterase-3, durch Stimulation ...
Stutz, Janine
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The Journal of Physiology, EarlyView.Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Cilostazol in Diabetic Neuropathy
, 2011 Peripheral neuropathy remains a major chronic complication of diabetes mellitus. Its pathogenesis mainly involves chronic glucose toxicity and nerve ischemia.
E. Maltezos, N. Papanas
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Cilostazol for Secondary Stroke Prevention: History, Evidence, Limitations, and Possibilities [PDF]
, 2021 Cilostazol is a PDE3 (phosphodiesterase III) inhibitor with a long track record of safety that is Food and Drug Administration and European Medicines Agency approved for the treatment of claudication in patients with peripheral arterial disease.
Johnston, S. Claiborne +12 more
core +1 more source
Cilostazol Strengthens Barrier Integrity in Brain Endothelial Cells [PDF]
, 2013 We studied the effect of cilostazol, a selective inhibitor of phosphodiesterase 3, on barrier functions of blood-brain barrier (BBB)-related endothelial cells, primary rat brain capillary endothelial cells (RBEC), and the immortalized human brain ...
Tanaka, Kunihiko +7 more
core +2 more sources
Risk of Delayed Post‐polypectomy Bleeding in Patients With Antithrombotic Therapy
DEN Open, Volume 7, Issue 1, April 2027.Antithrombotic therapy is associated with an increased risk of delayed post‐polypectomy bleeding after endoscopic resection of colorectal polyps ≤15 mm. Despite this increased risk, overall bleeding rates remain low in both per‐patient and per‐lesion analyses. ABSTRACT Objectives Recent changes in the perioperative management of antithrombotic therapy (
Rumiko Tsuboi +18 more
wiley +1 more source
Cilostazol for secondary stroke prevention: systematic review and meta-analysis
Stroke and Vascular Neurology, 2021 Background Stroke is one of the leading causes of death worldwide. Cilostazol, an antiplatelet and phosphodiesterase 3 inhibitor, has not been clearly established for ischaemic stroke use.
Leonard LL Yeo +7 more
doaj +1 more source
Preparation and in-vitro evaluation of cilostazol self-emulsifying drug delivery system
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2020 This work reported a first liquid self-nanoemulsifying drug delivery system (SEDD) of cilostazol using oleic acid as oil phase, tween 80 as surfactant, and transcutol as co-surfactant.
Ali N. Wannas, Nidhal K. Maraie
doaj +1 more source
Brain and Behavior, Volume 16, Issue 10, October 2026.ABSTRACT Objective To investigate the natural course of cerebral small vessel disease (CSVD) manifested as pure thalamic infarction (PTI) and identify predictors of 90‐day clinical prognosis and 1‐year recurrent major adverse cardiovascular/cerebrovascular events (MACE).
Huang Qiang, Cui Ying, Zhang Yongbo
wiley +1 more source