Results 1 to 10 of about 25,606 (192)
Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression [PDF]
BMC Cancer, 2008 Background Cimetidine, a histamine type-2 receptor antagonist, has been reported to inhibit the growth of glandular tumors such as colorectal cancer, however the mechanism of action underlying this effect is unknown.
Sakashita Hideaki +2 more
doaj +4 more sources
A comparison of oral omeprazole and intravenous cimetidine in reducing complications of duodenal peptic ulcer [PDF]
BMC Gastroenterology, 2006 Background Gastrointestinal bleeding is a common problem and its most common etiology is peptic ulcer disease. Ulcer rebleeding is considered a perilous complication for patients. To reduce the rate of rebleeding and to fasten the improvement of patients'
Khaleghian Farzaneh +4 more
doaj +3 more sources
Frontiers in Medicine, 2021 Previously, it was reported that multiple patients had hemolytic anemia associated with cimetidine administration, while only one patient who had received intravenous cimetidine was serologically diagnosed with drug-induced immune hemolytic anemia (DIIHA)
Yuanjun Wu +7 more
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Gastroenterology, 1979 This case of an adult with cimetidine-induced hepatitis is presented. An etiologic role for the drug was strongly suggested when the patient developed transient hepatic dysfunction after two reexposures to cimetidine, which reverted promptly on withdrawal of the drug.
J P, Villeneuve, H A, Warner
openaire +4 more sources
Journal of Tropical Pharmacy and Chemistry, 2016 Drugs used with foods or drinks can affect the drug effects. This study aims to observe the effect of papaya juice (Carica papaya L.) to the pharmacokinetics profile of cimetidine in white rats. The animal were randomly in three group.
Siti Julaicha +2 more
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Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo [PDF]
, 2007 Cysteine proteinases from the fruit and latex of plants, including papaya, pineapple and fig, were previously shown to have a rapid detrimental effect, in vitro, against the rodent gastrointestinal nematodes, H eligmosomoides polygyrus (which is found in
Behnke, J.M. +4 more
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Cimetidine-induced Male Reproductive Defects in Piroxicam-induced Gastric Ulcerated Wistar Rats and Their Amelioration by Melatonin [PDF]
The Iranian Journal of Veterinary Science and TechnologyCimetidine is a known reproductive toxicant due to its adverse effects on testicular function. Melatonin is an antioxidant that has a role in mitigating any disorders that could affect spermatogenesis.
Afisu Basiru +5 more
doaj +1 more source
Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms [PDF]
, 2012 Although large cholangiocytes exert their functions by activation of cyclic adenosine 3',5'-monophosphate (cAMP), Ca(2+)-dependent signaling regulates the function of small cholangiocytes. Histamine interacts with four receptors, H1-H4HRs.
Fanyin Meng +15 more
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Asian Journal of Andrology, 2017 The H2-receptor antagonist cimetidine is an antiulcer drug also used for the treatment of cancer due to its antiangiogenic effect. However, this drug has caused structural changes in the seminiferous tubules.
Flávia L Beltrame, Estela Sasso-Cerri
doaj +1 more source
Cimetidine Enhances Antigen-Specific IgE and Th2 Cytokine Production
Allergology International, 2011 Background: Treatment with anti-ulcer drugs has been shown to enhance IgE production against food antigens. However, little is known about the immunological effects of cimetidine, a histamine receptor type 2 (H2R) antagonist that is widely used as an ...
Ken Arae +7 more
doaj +1 more source