Cimetidine-induced Male Reproductive Defects in Piroxicam-induced Gastric Ulcerated Wistar Rats and Their Amelioration by Melatonin [PDF]
The Iranian Journal of Veterinary Science and TechnologyCimetidine is a known reproductive toxicant due to its adverse effects on testicular function. Melatonin is an antioxidant that has a role in mitigating any disorders that could affect spermatogenesis.
Afisu Basiru +5 more
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Asian Journal of Andrology, 2017 The H2-receptor antagonist cimetidine is an antiulcer drug also used for the treatment of cancer due to its antiangiogenic effect. However, this drug has caused structural changes in the seminiferous tubules.
Flávia L Beltrame, Estela Sasso-Cerri
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Evaluation of person-level heterogeneity of treatment effects in published multiperson N-of-1 studies: systematic review and reanalysis. [PDF]
, 2018 OBJECTIVE:Individual patients with the same condition may respond differently to similar treatments. Our aim is to summarise the reporting of person-level heterogeneity of treatment effects (HTE) in multiperson N-of-1 studies and to examine the evidence ...
Balk, Ethan M +8 more
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Cimetidine Enhances Antigen-Specific IgE and Th2 Cytokine Production
Allergology International, 2011 Background: Treatment with anti-ulcer drugs has been shown to enhance IgE production against food antigens. However, little is known about the immunological effects of cimetidine, a histamine receptor type 2 (H2R) antagonist that is widely used as an ...
Ken Arae +7 more
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Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms [PDF]
, 2012 Although large cholangiocytes exert their functions by activation of cyclic adenosine 3',5'-monophosphate (cAMP), Ca(2+)-dependent signaling regulates the function of small cholangiocytes. Histamine interacts with four receptors, H1-H4HRs.
Fanyin Meng +15 more
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Effects of temperature and wavelength choice on in-situ dissolution test of Cimetidine tablets
Journal of Pharmaceutical Analysis, 2013 The effects of temperature and wavelength choice on in-situ dissolution test instrument of Cimetidine were studied. Absorbance (A)
Xin-Xia Li +8 more
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A DFT study of the chemical reactivity of cimetidine A, C and D in the gas, H2O, MeOH and EtOH solvents [PDF]
Journal of the Serbian Chemical Society, 2017 % Fukui % DFT s KR nema In the present work, we have analyzed the chemical reactivity of cimetidine A, C and D in different solvents; through the evaluation of global and local DFT reactivity descriptors.
Mendoza Huizar Luis Humberto +4 more
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Spinal cystic echinococcosis - a systematic analysis and review of the literature : part 2. treatment, follow-up and outcome [PDF]
, 2013 Bone involvement in human cystic echinococcosis (CE) is rare, but affects the spine in approximately 50% of cases. Despite significant advances in diagnostic imaging techniques, surgical treatment and introduction of pharmacological therapy, spinal ...
Blum, Johannes +4 more
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Canadian Journal of Gastroenterology, 1994 The objective of this study was to compare the effect of cimetidine 200 mg tablet with that of cimetidine suspension (200 mg/10 mL), a 20 mL suspension of 800 mg magnesium hydroxide and 912 mg aluminum hydroxide, and matching placebo on intragastric pH ...
ABR Thomson +4 more
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Pharmacokinetic Drug-Drug Interaction and Responsible Mechanism between Memantine and Cimetidine
Pharmaceutics, 2018 A sensitive and simple chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to evaluate memantine in rat plasma. Memantine and propranolol (internal standard) in rat plasma was extracted using a methanol precipitation method.
Young A. Choi +2 more
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