Results 61 to 70 of about 34,140 (239)
Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics [PDF]
, 2015 Membrane transporters play an essential role in the transport of endogenous and exogenous compounds, and consequently they mediate the uptake, distribution, and excretion of many drugs. The clinical relevance of transporters in drug disposition and their
Knibbe, C.A.J. (Catherijne) +6 more
core +8 more sources
Protective assessment of cimetidine against cyclophosphamide-induced kidney injury
Asian Journal of Medical Sciences, 2018 Background: Nephrotoxicity is one of the frequent toxicities observed with cyclophosphamide (CP) use which may involve oxidative stress. Cimetidine is an antihistamine with anti-oxidative stress activity.
Elias Adikwu , Bonsome Bokolo
doaj +1 more source
Equine Veterinary Journal, EarlyView.Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik +2 more
wiley +1 more source
Response to cimetidine in a 1-year-old child with PFAPA syndrome
The Turkish Journal of Pediatrics, 2016 Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is characterized by periodic febrile attacks recurring regularly every 2 to 8 weeks.
Kazuto Taniguchi +4 more
doaj +1 more source
Erythropoietic protoporphyria: case reports for clinical and therapeutic hints
Italian Journal of Pediatrics, 2023 Background Erythropoietic protoporphyria is a rare disorder which represents an important health problem in children, causing painful photosensitivity. Little is known on the correlation between genetic profile and clinical manifestations.
Cristina Tumminelli +8 more
doaj +1 more source
Regulation of gastric acid secretion in situ by an endogenous activator protein: Studies with activator-specific antibody [PDF]
, 2013 Monospecific polyclonal antibody was raised against a homogenous preparation of endogenous activator protein (HAF) for the gastric H+,K+-ATPase system.
Tushar K. Ray, Jyotirmoy Nandi, Larry F. Lemanski and Swapan K. Ghosh
core +1 more source
International Journal of Dermatology, EarlyView.ABSTRACT Grzybowski's generalized eruptive keratoacanthoma (GEKA) is a rare variant of keratoacanthomas, characterized by hundreds to thousands of lesions, accompanied by pruritus, mucosal involvement, and comorbidities. Our aim was to analyze the clinical presentation, associated comorbidities, treatment strategies, and outcomes of GEKA.
Nicholas Florin Kormos +6 more
wiley +1 more source
Effect of an antiandrogenic H
, 1988 Because biochemical 'feminization' of the liver in males is observed with hepatic regeneration and because the hepatic regenerative response in females is greater than that in males, the posibility that antiandrogens might potentiate liver regeneration ...
Chapchap, P +7 more
core
Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review
Food Frontiers, Volume 7, Issue 2, March 2026.ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva +9 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 314-317, February 2026.Physiology Based Pharmacokinetic (PBPK) modeling is an established essential tool for predicting and/or analyzing drug–drug interactions (DDI). Uncertainty and variability associated with in vitro determined DDI‐related parameters have often been considered a limitation for predicting PBPK‐DDIs.
Kunal S. Taskar +2 more
wiley +1 more source