Results 71 to 80 of about 34,140 (239)
Background Gastrointestinal bleeding is a common problem and its most common etiology is peptic ulcer disease. Ulcer rebleeding is considered a perilous complication for patients. To reduce the rate of rebleeding and to fasten the improvement of patients'
Khaleghian Farzaneh +4 more
doaj +1 more source
Effect of cimetidine, ranitidine, famotidine and omeprazole on hepatocyte proliferation in vitro [PDF]
Recently reports have indicated that both cimetidine and ranitidine delay cell proliferation in rats following 70% partial hepatectomy and result in an increased mortality following this procedure.
A. Amoruso +58 more
core +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
ABSTRACT Vildagliptin (VDG) is a dipeptidyl‐peptidase‐4 (DPP‐4) inhibitor used for type 2 diabetes (T2DM) treatment. Viewing to improve VDG treatment, a population pharmacokinetic (popPK) model was built to describe drug plasma, free liver and muscle concentrations determined by microdialysis in healthy and diabetic animals following 50 mg/kg i.v ...
Bruna Bernar Dias +2 more
wiley +1 more source
The role of endocardial endothelium in the effect of histamine on myocardial contractions of histamine H1 and H2 receptor blockade [PDF]
Endocardial endothelium (EE) is a barrier which controls the passage of macromolecules and fluids between the blood and the adjacent miocardial interstitium. At the same time it is the place of synthesis of numerous endothelial mediators. Histamine as an
Smiljić Sonja +4 more
doaj +1 more source
Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy
Background: A previous study indicated that Balkan endemic nephropathy (BEN) patients in the early stage of the disease had significantly higher creatinine clearance (Ccr) than healthy persons.
Ljubica Djukanović +4 more
doaj +1 more source
Penile warts: an update on their evaluation and management
Background: Penile warts are the most common sexually transmitted disease in males. Clinicians should be familiar with the proper evaluation and management of this common condition.
Alexander KC Leung +3 more
doaj +1 more source
Mortality study of 18 000 patients treated with omeprazole. [PDF]
Background: The long term safety of potent gastric acid suppressive therapy has yet to be established. Method: General practice record review at a median interval of 26 months followed by retrieval of details of all deaths within four years using the ...
Bateman, D.N. +9 more
core
The management of chronic pain in pregnancy
Key content Chronic pain is of increasing relevance in clinical practice and may affect a significant proportion of pregnant women. Effective management demands a balance between adequate pain control and minimisation of risks to the fetus. Chronic pain medicines have varying safety profiles with regard to teratogenicity, pregnancy outcomes and ...
Lawrence Hutchinson +5 more
wiley +1 more source
Effect of cimetidine on cyclophosphamide-induced liver toxicity in albino rats
Background: The clinical use of cyclophosphamide (CP) has been characterised by liver toxicity. Aims and Objectives: This research assessed the effect of cimetidine against CP-induced liver toxicity in a rat model. Material and Methods: Forty eight
Elias Adikwu , Bonsome Bokolo
doaj +1 more source

