The present study aimed to synthesize iron oxide nanoparticles loaded with quinine and alkaloids-rich Cinchona officinalis (Peruvian bark) stem bark extract, and further evaluate their cytotoxic effect and apoptosis mechanisms in MCF-7 breast cancer ...
Laila Naif Al-Harbi +5 more
doaj +2 more sources
Dimeric Cinchona alkaloids [PDF]
Nature is full of dimeric alkaloids of various types from many plant families, some of them with interesting biological properties. However, dimeric Cinchona alkaloids were not isolated from any species but were products of designed partial chemical synthesis.
Przemysław J. Boratyński
core +4 more sources
Cinchona Urea-Catalyzed Asymmetric Sulfa-Michael Reactions: The Brønsted Acid-Hydrogen Bonding Model. [PDF]
This is the final version of the article. It first appeared from the American Chemical Society via http://dx.doi.org/10.1021/jacs.6b05074The cinchona alkaloid-derived urea-catalyzed asymmetric conjugate addition of aromatic thiols to cycloalkenones was ...
Grayson, Matthew N, Houk, KN
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Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani [PDF]
This study investigates the antifungal properties of a liquid Cinchona-Based Formulation (CBF) against Rhizoctonia solani. CBF, a stable acidic extract of Cinchona bark (0.1 N HCl), effectively suppressed mycelial growth (58.75 ± 0.48%) and sclerotia ...
Simanta Das +9 more
doaj +2 more sources
For the last six decades, researchers have been focused on finding efficient reactivators of organophosphorus compound (OP)-inhibited acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). In this study, we have focused our research on a new oxime
Maja Katalinić +5 more
doaj +2 more sources
Recent applications of <em>Cinchona</em> alkaloid-based catalysts in asymmetric addition reactions
: This review documents recently developed asymmetric addition reactions catalyzed by natural Cinchona alkaloids and their derivatives. These reactions include direct nucleo-philic additions across the carbon–oxygen double bond and the carbon–nitrogen ...
Girija Singh, Elizabeth M. O. Yeboah
openalex +3 more sources
A Review: Pharmacological Activities of Quinoline Alkaloid of Cinchona sp.
Cinchona is a plant used in traditional malaria treatment. This review aims to examine pharmacological activities to increase the benefits and uses of the bioactive compounds found in the bark of the Cinchona trees as medicine and cosmetics. A literature
Hariyanti Hariyanti +3 more
semanticscholar +1 more source
<i>Cinchona</i> alkaloid copolymers as fluorimetric INHIBIT and colorimetric AND logic gates for detection of iodide. [PDF]
Agius N +3 more
europepmc +3 more sources
13 3172.56 km 2 ) and 19.20 % (24 7371.32 km 2 ) of Peru ’ s surface area had high ( > 0.6) and moderate (0.4 – 0.6) probabilities, respectively, of hosting Cinchona.
L. García +4 more
semanticscholar +1 more source
The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]
Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Docampo +56 more
core +4 more sources

