Results 1 to 10 of about 30,754 (301)

Cinchona officinalis Phytochemicals-Loaded Iron Oxide Nanoparticles Induce Cytotoxicity and Stimulate Apoptosis in MCF-7 Human Breast Cancer Cells

open access: yesNanomaterials, 2022
The present study aimed to synthesize iron oxide nanoparticles loaded with quinine and alkaloids-rich Cinchona officinalis (Peruvian bark) stem bark extract, and further evaluate their cytotoxic effect and apoptosis mechanisms in MCF-7 breast cancer ...
Laila Naif Al-Harbi   +5 more
doaj   +2 more sources

Dimeric Cinchona alkaloids [PDF]

open access: yesMolecular Diversity, 2015
Nature is full of dimeric alkaloids of various types from many plant families, some of them with interesting biological properties. However, dimeric Cinchona alkaloids were not isolated from any species but were products of designed partial chemical synthesis.
Przemysław J. Boratyński
core   +4 more sources

Cinchona Urea-Catalyzed Asymmetric Sulfa-Michael Reactions: The Brønsted Acid-Hydrogen Bonding Model. [PDF]

open access: yesJournal of the American Chemical Society, 2016
This is the final version of the article. It first appeared from the American Chemical Society via http://dx.doi.org/10.1021/jacs.6b05074The cinchona alkaloid-derived urea-catalyzed asymmetric conjugate addition of aromatic thiols to cycloalkenones was ...
Grayson, Matthew N, Houk, KN
core   +4 more sources

Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani [PDF]

open access: yesScientific Reports
This study investigates the antifungal properties of a liquid Cinchona-Based Formulation (CBF) against Rhizoctonia solani. CBF, a stable acidic extract of Cinchona bark (0.1 N HCl), effectively suppressed mycelial growth (58.75 ± 0.48%) and sclerotia ...
Simanta Das   +9 more
doaj   +2 more sources

New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds

open access: yesMolecules, 2017
For the last six decades, researchers have been focused on finding efficient reactivators of organophosphorus compound (OP)-inhibited acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). In this study, we have focused our research on a new oxime
Maja Katalinić   +5 more
doaj   +2 more sources

Recent applications of <em>Cinchona</em> alkaloid-based catalysts in asymmetric addition reactions

open access: diamond, 2016
: This review documents recently developed asymmetric addition reactions catalyzed by natural Cinchona alkaloids and their derivatives. These reactions include direct nucleo-philic additions across the carbon–oxygen double bond and the carbon–nitrogen ...
Girija Singh, Elizabeth M. O. Yeboah
openalex   +3 more sources

A Review: Pharmacological Activities of Quinoline Alkaloid of Cinchona sp.

open access: yesBiointerface Research in Applied Chemistry, 2022
Cinchona is a plant used in traditional malaria treatment. This review aims to examine pharmacological activities to increase the benefits and uses of the bioactive compounds found in the bark of the Cinchona trees as medicine and cosmetics. A literature
Hariyanti Hariyanti   +3 more
semanticscholar   +1 more source

World historical mapping and potential distribution of Cinchona spp. in Peru as a contribution for its restoration and conservation

open access: yesJournal for Nature Conservation, 2022
13 3172.56 km 2 ) and 19.20 % (24 7371.32 km 2 ) of Peru ’ s surface area had high ( > 0.6) and moderate (0.4 – 0.6) probabilities, respectively, of hosting Cinchona.
L. García   +4 more
semanticscholar   +1 more source

The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]

open access: yes, 2002
Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Docampo   +56 more
core   +4 more sources

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