Results 41 to 50 of about 30,773 (318)
Quantitative determination of major alkaloids in Cinchona bark by Supercritical Fluid Chromatography
Chinoline alkaloids found in Cinchona bark still play an important role in medicine, for example as anti-malarial and antiarrhythmic drugs. For the first time Supercritical Fluid Chromatography has been utilized for their separation.
Adele Murauer, M. Ganzera
semanticscholar +1 more source
In Silico Screening and Designing Synthesis of Cinchona Alkaloids Derivatives as Potential Anticancer [PDF]
P-glycoprotein (P-gp) resistance in cancer cells decreases intracellular accumulation of various anticancer drugs. This multidrug resistance (MDR) protein can be modulated by a number of non-cytotoxic drugs.
Hanafi, M. (Muhammad) +4 more
core +2 more sources
We report density functional theory calculations that examine the mechanism and origins of stereoselectivity of Soós' landmark discovery from 2005 that cinchona thioureas catalyze the asymmetric Michael addition of nitroalkanes to enones.
Matthew N. Grayson
semanticscholar +1 more source
Cinchona ledgeriana produces several secondary metabolites. The main quinoline alkaloid, quinine that is widely used as an antimalarial drug, is most commonly extracted from the bark of Cinchona, and its leaves contain several other metabolites.
Dian Rahma Pratiwi +2 more
doaj +1 more source
Maladies des arbres à quinquina en Guinée française [PDF]
Chevaugeon Jean, Merny Georges. Maladies des Arbres à Quinquina en Guinée Française. In: Journal d'agriculture tropicale et de botanique appliquée, vol. 3, n°11, novembre 1956. pp.
Chevaugeon, Jean, Merny, Georges
core +1 more source
Considerable inter- and intraspecific variation with respect to the quantity and composition of plant natural products exists. The processes that drive this variation remain largely unknown.
Carla Maldonado +7 more
semanticscholar +1 more source
Composite materials based on metal nanoparticles supported on a naturally occurring nanotubular clay, halloysite (HAL), led to the diastereoselective hydrogenation of tetra‐substituted alkenes under relatively smooth conditions, mainly oxazolidinone‐based heterocycles.
Rosa Pich +9 more
wiley +1 more source
Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts
Cinchona alkaloids with a free 6'-OH functionality are being increasingly used within asymmetric organocatalysis. This fascinating class of bifunctional catalyst offers a genuine alternative to the more commonly used thiourea systems and because of the ...
Laura A. Bryant +2 more
doaj +1 more source
Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance
This review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Luigi Dolcini +3 more
wiley +1 more source
The mechanism of the enantioselective sulfa-Michael addition reaction catalyzed by a cinchona alkaloid-squaramide bifunctional organocatalyst was studied using density functional theory (DFT). Four possible modes of dual activation mechanism via hydrogen
Jinlong Guo, M. W. Wong
semanticscholar +1 more source

