Results 41 to 50 of about 920 (164)

Frequency of Chlamydia trachomatis infection in cervical intraepithelial lesions and the status of cytological p16/Ki-67 dual-staining [PDF]

, 2017
Background: Chlamydia trachomatis (Ct) is not a disease subject to mandatory reporting in Brazil, and the prevalence rate of this genital infection varies according to the region in which studies are conducted, as well as by the detection technique ...
A Longatto Filho, A. Longatto-Filho, AB Moscicki, AL Abreu de, C Bergeron, C Santos, C. M. Roteli-Martins, D Motta, D. Stauffert, E. C. Baracat, G. G. Ribeiro, I. M. Linhares, J Ordi, J Silva, JS Smith, K Nanda, K Owusu-Edusei Jr, KE Jensen, LB Fernandes, M Pantoja, M Safaeian, M. A. Zonta, M. F. Silveira, M. Tacla, MI Rosa, ML Shew, N Low, N Wentzensen, PA Magalhaes, R. Robial, RC Piazzetta, SM Redmond, T Luostarinen   +32 more
core   +3 more sources

Evaluation of p16/Ki-67 dual staining compared with HPV genotyping in anal cytology with diagnosis of ASC-US for detection of high-grade anal intraepithelial lesions

Journal of Cytology, 2019
Introduction: Human Papillomavirus (HPV) infection is the main risk factor for anogenital cancer. The objective of this study was to compare p16/Ki-67 dual staining to HPV genotyping in anal cytology samples with an atypical squamous cell of undetermined
Maxime Pichon, Marie Joly, Frédérique Lebreton, Medhi Benchaïb, Yahia Mekki, Mojgan Devouassoux-Shisheboran   +5 more
doaj   +1 more source

p16/Ki-67 dual staining has a better accuracy than human papillomavirus (HPV) testing in women with abnormal cytology under 30 years old

Biomolecules & Biomedicine, 2019
Due to a high rate of transient human papillomavirus (HPV) infection, HPV genotyping has a low specificity for high-grade cervical lesions, especially in young women.
Laurențiu Pirtea, Cristina Secosan, Madalin Margan, Lavinia Moleriu, Oana Balint, Dorin Grigoras, Ioan Sas, Florin Horhat, Adelina Jianu, Răzvan Ilina   +9 more
doaj   +1 more source

Performance of p16INK4a ELISA as a primary cervical cancer screening test among a large cohort of HIV-infected women in western Kenya: a 2-year cross-sectional study. [PDF]

, 2016
ObjectiveA biomarker with increased specificity for cervical dysplasia compared with human papillomavirus (HPV) testing would be an attractive option for cervical cancer screening among HIV-infected women in resource-limited settings. p16(INK4a) has been
Huchko, Megan J, Maloba, May, Reuschenbach, Miriam, Smith-McCune, Karen, von Knebel Doeberitz, Magnus, Wu, Tara J   +5 more
core   +1 more source

Head and neck squamous cell carcinoma of unknown primary: Neck dissection and radiotherapy or definitive radiotherapy [PDF]

, 2014
Background Management of head and neck carcinoma from unknown primary (HNCUP) remains controversial, with neck dissection and radiotherapy (RT) or definitive RT both commonly used.
Ang, Armas, Aslani, Bernier, Braud, Chaturvedi, Christiansen, Colletier, Coster, Dagan, Davidson, Denis, El-Mofty, Erkal, Forastiere, Frank, Freeman, Grau, Iganej, Lee, Macdonald, Machtay, Mack, Maxwell, Mendenhall, Miller, Nguyen, Nieder, Park, Patel, Perkins, Punwaney, Reddy, Strojan, Tribius, Wallace, Walter, Weir, Zengel   +38 more
core   +1 more source

Transoral laser microsurgery for oropharyngeal squamous cell carcinoma: A paradigm shift in therapeutic approach [PDF]

, 2016
Background: The contemporary treatment of oropharyngeal squamous cell carcinoma (SCC) is an area of debate. We report outcomes of a minimally invasive approach involving transoral laser microsurgery (TLM).
Ang, Bernier, Bernier, Calais, Canis, Cmelak, Cooper, Fakhry, Gillespie, Grant, Greven, Haughey, Hong, Huang, Huang, Jensen, Lewis, Licitra, Machtay, McCombe, Mehanna, Mehanna, More, Nasman, Nguyen, O'Hara, O'Leary, Parsons, Patel, Patel, Patterson, Rackley, Rich, Schache, Setton, Setton, Shaw, Shiley, Sinha, Steiner, Steiner, Thomas, Trotti   +42 more
core   +1 more source

Efficiency of p16 and Ki-67 immunostaining for detecting premalignant cervical lesions in high risk population [PDF]

, 2021
Background: This study aimed to evaluate the efficiency of immunostaining with p16 and Ki-67 in cervical cytology specimens for the detection of cervical intraepithelial neoplasia (CIN) in a high risk population.Methods: This was a prospective review of ...
Arioz, Dagistan Tolga, Cura, Gizem, Kanat-Pektas, Mine, Ozdemir, Cigdem, Sahin, Bugra   +4 more
core   +2 more sources

Human papillomavirus (HPV) related Oropharynx Cancer in the United Kingdom – An evolution in the understanding of disease aetiology [PDF]

, 2016
A rising incidence of oropharyngeal squamous cell carcinoma (OPSCC) incidence has occurred throughout the developed world, where it has been attributed to an increasing impact of human papillomavirus (HPV) on disease etiology.
Brougham, Kath, Cubie, Heather, Cuschieri, Kate, Evans, Mererid, Harrington, Kevin, James, Jacqueline A, Jones, Terry M, Junor, Elizabeth, King, Emma V, Lau, Andy S, Leary, Sam, Long, Anna, McCance, Dennis J, Mehanna, Hisham, Monaghan, Hannah, Moran, Michael, Ness, Andy R, Nutting, Christopher M, Oguejiofor, Ken, Powell, Ned, Pring, Miranda, Rapozo, Davy, Robinson, Max, Schache, Andrew G, Schick, Ulrike, Shaw, Richard J, Sheard, Jon, Sloan, Phil, Thomas, Gareth, Thomas, Steve, Upile, Navdeep, West, Catharine ML   +31 more
core   +5 more sources

Prognostic and diagnostic validity of p16/Ki-67, HPV E6/E7 mRNA, and HPV DNA in women with ASCUS: a follow-up study

Virology Journal, 2019
Background We evaluated the prognostic and diagnostic ability of p16/Ki-67 immunocytochemistry, HPV E6/E7 mRNA testing and HPV DNA assay in triaging ASCUS to find a way to manage cervical lesions more effectively. Methods We conducted a prospective study
Chenchen Ren, Yuanhang Zhu, Li Yang, Xiaoan Zhang, Ling Liu, Zhaoxin Wang, Dongyuan Jiang   +6 more
doaj   +1 more source

Health care policy trial of primary human papillomavirus–based cervical screening in Denmark: Comparison of three triage algorithms

International Journal of Cancer, EarlyView.
What's New? Primary human papillomavirus (HPV)–based screening has shown superiority to cytology‐based screening in reducing cervical cancer risk in clinical trials. However, the benefit must be balanced with potential overdiagnosis/overtreatment.
Jeppe Bennekou Schroll, Jesper Bonde, Elsebeth Lynge, Marianne Waldstrøm, Petra Hall Viborg, Anna Frandsen, Rikke Holst Andersen, Susanne Merete Nielsen, Bettina Kjær Kristensen, Doris Schledermann, Berit Andersen, on behalf ofthe National Danish Cervical Cancer Screening Steering Committee   +11 more
wiley   +1 more source