Results 121 to 130 of about 113,368 (254)

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

open access: yesJournal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed   +1 more
wiley   +1 more source

Serogroup A Neisseria meningitidis with Reduced Susceptibility to Ciprofloxacin

open access: yesEmerging Infectious Diseases, 2008
Jacob Strahilevitz   +5 more
doaj   +1 more source

Nitric Oxide Tunes Secreted Metabolite Bioactivity

open access: yesMolecular Microbiology, EarlyView.
Pseudomonas aeruginosa produces phenazine metabolites that can react with nitric oxide (·NO) to form nitrosylated compounds. The formation of these metabolites results in rapid loss in P. aeruginosa viability and diminishes phenazine antimicrobial activity against other organisms, including Staphylococcus aureus. ABSTRACT The radical nitric oxide (·NO)
Zachery R. Lonergan   +7 more
wiley   +1 more source

The Synergy Between a Silver‐Ruthenium Antimicrobial and Aminoglycosides Is Based on Severe Macromolecular Damage

open access: yesMolecular Microbiology, EarlyView.
AGXX enhances aminoglycoside activity against multidrug‐resistant pathogens such as uropathogenic Escherichia coli by increasing reactive oxygen species, causing protein aggregation and DNA damage. This effect is reduced by oxygen limitation or antioxidants. Polyphosphate protects cells from oxidative damage.
Emmanuel P. Oladokun   +9 more
wiley   +1 more source

The effects of far‐UVC irradiation on the presence and concentration of ESKAPEE pathogens on hospital surfaces: Study protocol for a multi‐site, double‐blinded randomized controlled trial in La Paz, Bolivia

open access: yesPhotochemistry and Photobiology, EarlyView.
The protocol of a multi‐site, double‐blinded, clustered randomized controlled trial (cRCT) with a binary outcome of the presence of viable presumptive ESKAPEE pathogens on surfaces in and around hospital sinks is to be implemented in two Bolivian hospitals.
Lindsay B. Saber   +14 more
wiley   +1 more source

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

open access: yesPeriodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source

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