Results 21 to 30 of about 469 (131)

Determination of the Median Effective Dose (ED50) of Ciprofol for Successful Sedation in Pediatric Patients During General Anesthesia Induction [PDF]

Drug Design, Development and Therapy
Peihe Nie,1 Di Wu,2 Chengjun Du,1 Xiaoqian Wang,1 Huan Zhang,1 Hongyi Xiao1 1Department of Anesthesiology, Weifang People’s Hospital, Weifang, 261041, People’s Republic of China; 2Department of Outpatient, Weifang People’s Hospital, Weifang, 261041 ...
Nie P, Wu D, Du C, Wang X, Zhang H, Xiao H   +5 more
doaj   +2 more sources

Intravenous Anesthesia with Ciprofol and Remimazolam Besylate for Painless Gastroscopy: A Prospective, Single-Center, Randomized Controlled Trial [PDF]

Drug Design, Development and Therapy
Lin Li,* Yusi Zhu,* Jie Zhu, Mingyue Zeng, Yu Duan, Pengfei Cheng, Xiang Zhou Department of Anesthesiology, General Hospital of Central Theater Command of PLA, Wuhan, People’s Republic of China*These authors contributed equally to
Li L, Zhu Y, Zhu J, Zeng M, Duan Y, Cheng P, Zhou X   +6 more
doaj   +2 more sources

Efficacy and safety of ciprofol for the induction of general anesthesia in patients with obesity undergoing laparoscopic sleeve gastrectomy: A double-blind randomized, controlled study. [PDF]

PLoS ONE
BackgroundThe selection of safe and effective anesthetic agents for patients undergoing bariatric surgery is vital. This study aimed to evaluate the efficacy and safety of ciprofol in inducing general anesthesia in patients with obesity undergoing ...
Xiaowei Chi, Yi Xu, Qiang Li, Keshu Xia, Qiang Fu   +4 more
doaj   +2 more sources

Safety and efficacy of ciprofol versus propofol for gastrointestinal endoscopy: a meta-analysis

BMC Gastroenterology
Background The role of ciprofol as a novel anesthetic in gastrointestinal endoscopic surgery is unclear. We conducted a systematic review and meta-analysis to evaluate the efficacy and safety of ciprofol for gastrointestinal endoscopy in patients aged ...
Xi Cheng, Pengyu Zhang, Dan Jiang, Baoxia Fang, Fuchao Chen   +4 more
doaj   +3 more sources

Efficacy and safety of ciprofol versus propofol for anesthesia in patients undergoing gastrointestinal endoscope: a systematic review and meta-analysis of randomized controlled trials (RCT) [PDF]

BMC Anesthesiology
Background Ciprofol is considered an alternative to propofol and can be used to achieve anesthesia at a lower dose with a lower incidence of adverse events.
Zhaoxuan Wang, Siru Wang, Lu Liu, Xiaolu Zhang, Meijuan Ren, Qianqian Zhang, Chang Liu   +6 more
doaj   +2 more sources

Effects of Voriconazole on the Safety, Pharmacokinetics and Pharmacodynamics of Ciprofol (HSK3486), a Novel Intravenous Anaesthetic, in Healthy Participants: A Prospective, Randomized, Crossover Clinical Trial [PDF]

Drug Design, Development and Therapy
Yicong Bian,1,2,* Tao Hu,1,2,* Qingqing Deng,1,3,* Sheng Ma,1,2 Yongyi Jiao,4 Jian Shi,1,2 Nan Jiang,5 Mengyue Hu,6 Yongrui Wang,6 Xiao Liu,6 Zihan Zhang,7 Chenrong Huang,1,2 Hua Zhang,1,2 Liyan Miao1,2 1Department of Pharmacy ...
Bian Y, Hu T, Deng Q, Ma S, Jiao Y, Shi J, Jiang N, Hu M, Wang Y, Liu X, Zhang Z, Huang C, Zhang H, Miao L   +13 more
doaj   +1 more source

Comparison of ciprofol (HSK3486) versus propofol for the induction of deep sedation during gastroscopy and colonoscopy procedures: A multi‐centre, non‐inferiority, randomized, controlled phase 3 clinical trial

Basic &Clinical Pharmacology &Toxicology, Volume 131, Issue 2, Page 138-148, August 2022., 2022
Abstract Ciprofol is a propofol analogue with improved pharmacokinetic properties. A multi‐centre, non‐inferiority trial was conducted to compare the deep sedation properties of ciprofol and propofol with a non‐inferiority margin of 8% in patients undergoing gastroscopy and colonoscopy.
Junxiang Li, Xiao Wang, Jin Liu, Xia Wang, Xiangkui Li, Yaping Wang, Wen Ouyang, Jun Li, Shanglong Yao, Zhaoqiong Zhu, Qulian Guo, Yonghao Yu, Jinhai Meng, Yunxia Zuo   +13 more
wiley   +1 more source

Comparison and Clinical Value of Ciprofol and Propofol in Intraoperative Adverse Reactions, Operation, Resuscitation, and Satisfaction of Patients under Painless Gastroenteroscopy Anesthesia

Contrast Media &Molecular Imaging, Volume 2022, Issue 1, 2022., 2022
Objective. To investigate the comparison and clinical value of ciprofol and propofol for painless gastroenteroscopy anesthesia in terms of intraoperative adverse reactions, operation, resuscitation, and satisfaction of patients. Methods. A total of 96 patients who underwent painless gastroenteroscopy anesthesia in our hospital from June 2021 to January
Xingqu Chen, Ping Guo, Li Yang, Zhuoling Liu, Deshui Yu, Yuvaraja Teekaraman   +5 more
wiley   +1 more source

Study on the effectiveness and safety of ciprofol in anesthesia in gynecological day surgery: a randomized double-blind controlled study

BMC Anesthesiology, 2023
Backgroud ciprofol is a new type of intravenous anesthetic, which is a tautomer of propofol, with the characteristics of less injection pain, less respiratory depression and higher potency, but little clinical experience.
Yan Man, Hongyi Xiao, Teng Zhu, Fanceng Ji   +3 more
doaj   +1 more source

Effect of ciprofol on swallowing function in patients undergoing painless gastrointestinal endoscopy

Medicine, 2023
Background: Gastroscopy is one of the most commonly used diagnostic modalities for upper gastrointestinal disorders. This study compared the effect of ciprofol and propofol on swallowing function during painless gastroenteroscopy.
Jinsong Liao, Shun Lv, Xiong Wang, Yu Ye, Qiuyu Zhang, Lin Zeng, Shuhua Dong   +6 more
openaire   +2 more sources