Results 11 to 20 of about 515,053 (332)
Circadian clocks and breast cancer [PDF]
, 2016 Circadian clocks respond to environmental time cues to coordinate 24-hour oscillations in almost every tissue of the body. In the breast, circadian clocks regulate the rhythmic expression of numerous genes.
Blakeman, V +3 more
core +2 more sources
Dendritic cells direct circadian anti-tumour immune responses
Nature, 2022 Rhythmic trafficking of dendritic cells to the tumour draining lymph node governs a circadian response of tumour-antigen-specific CD8^+ T cells that is dependent on the circadian expression of the co-stimulatory molecule CD80.
Chen Wang +20 more
semanticscholar +1 more source
Metabolic Effects of Bariatric Surgery in Mouse Models of Circadian Disruption [PDF]
, 2015 Background/Objectives: Mounting evidence supports a link between circadian disruption and metabolic disease. Humans with circadian disruption (for example, night-shift workers) have an increased risk of obesity and cardiometabolic diseases compared with ...
Arble, Deanna M. +4 more
core +3 more sources
Circadian control of brain glymphatic and lymphatic fluid flow
Nature Communications, 2020 The glymphatic system is a network of perivascular spaces that promotes movement of cerebrospinal fluid (CSF) into the brain and clearance of metabolic waste.
L. Hablitz +8 more
semanticscholar +1 more source
Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenance. [PDF]
, 2019 Circadian clocks control daily rhythms in behavior and physiology. In Drosophila, the small ventral lateral neurons (sLNvs) expressing PIGMENT DISPERSING FACTOR (PDF) are the master pacemaker neurons generating locomotor rhythms.
Cai, Yao +8 more
core +1 more source
Biomolecular Concepts, 2014 Abstract Daily rhythms of light/darkness, activity/rest and feeding/fasting are important in human physiology and their disruption (for example by frequent changes between day and night shifts) increases the risk of disease. Many of the diseases found to be associated with such disrupted circadian lifestyles, including cancer ...
Jensen Lasse Dahl +2 more
openaire +3 more sources
The Melanocortin-4 Receptor Integrates Circadian Light Cues and Metabolism [PDF]
, 2015 The melanocortin system directs diverse physiological functions from coat color to body weight homoeostasis. A commonality among melanocortin-mediated processes is that many animals modulate similar processes on a circannual basis in response to longer ...
Arble, Deanna M. +10 more
core +2 more sources
Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]
, 2018 Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco +3 more
core +1 more source
Circadian desynchronization [PDF]
Interface Focus, 2010 The suprachiasmatic nucleus (SCN) coordinates via multiple outputs physiological and behavioural circadian rhythms. The SCN is composed of a heterogeneous network of coupled oscillators that entrain to the daily light–dark cycles. Outside the physiological entrainment range, rich locomotor patterns of desynchronized rhythms are observed.
Adrián E, Granada +3 more
openaire +2 more sources
FLOWERING LOCUS C -dependent and -independent regulation of the circadian clock by the autonomous and vernalization pathways [PDF]
, 2006 Background The circadian system drives pervasive biological rhythms in plants. Circadian clocks integrate endogenous timing information with environmental signals, in order to match rhythmic outputs to the local day/night cycle.
Amasino, Richard M. +5 more
core +4 more sources