Results 41 to 50 of about 100,006 (157)

Non-alcoholic Fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms. [PDF]

open access: yes, 2014
Emerging evidence suggests that maternal obesity (MO) predisposes offspring to obesity and the recently described non-alcoholic fatty pancreas disease (NAFPD) but involved mechanisms remain unclear.
Mouralidarane Angelina   +75 more
core   +1 more source

NREM delta power and AD-relevant tauopathy are associated with shared cortical gene networks

open access: yesScientific Reports, 2021
Reduced NREM sleep in humans is associated with AD neuropathology. Recent work has demonstrated a reduction in NREM sleep in preclinical AD, pointing to its potential utility as an early marker of dementia.
Joseph R. Scarpa   +5 more
doaj   +1 more source

Circadian light

open access: yesJournal of Circadian Rhythms, 2010
The present paper reflects a work in progress toward a definition of circadian light, one that should be informed by the thoughtful, century-old evolution of our present definition of light as a stimulus for the human visual system. This work in progress is based upon the functional relationship between optical radiation and its effects on nocturnal ...
Rea, Mark S   +3 more
openaire   +5 more sources

Novel mechanisms operating in the central pacemaker and in the light-synchronization pathway of Drosophila’s circadian clock [PDF]

open access: yes, 2011
PhDMost organisms display circadian rhythms of approximately 24 hours in many aspects of their physiology and behaviour. The synchronization between their internal rhythm and the environmental light-dark cycles is essential for an organism’s survival ...
Chen, Ko-Fan
core   +2 more sources

Isolation of new genes involved in temperature synchronization of the circadian clock of Drosophila melanogaster [PDF]

open access: yes, 2010
PhDCircadian clocks regulate behaviour and physiology of many organisms and keep them in synchrony with the environment. Drosophila's circadian clock is mainly synchronized by natural light-dark cycles and temperature fluctuations, both at molecular
Simoni, Alekos
core   +3 more sources

COMPASS: Continuous Open Mouse Phenotyping of Activity and Sleep Status [version 2; referees: 3 approved, 1 approved with reservations]

open access: yesWellcome Open Research, 2017
Background: Disruption of rhythms in activity and rest occur in many diseases, and provide an important indicator of healthy physiology and behaviour. However, outside the field of sleep and circadian rhythm research, these rhythmic processes are rarely ...
Laurence A. Brown   +3 more
doaj   +1 more source

Research on left atrial appendage thrombogenic milieu prediction model in patients with nonvalvular atrial fibrillation based on machine learning algorithm

open access: yesBMC Cardiovascular Disorders
Objective To establish a machine-learning model of left atrial appendage thrombogenic milieu (LAATM) in patients with nonvalvular atrial fibrillation (NVAF), and analyze the corresponding risk factors to guide clinical decision-making.
Ling Song   +10 more
doaj   +1 more source

Evaluation of Changes in Social Isolation and Loneliness with Incident Cardiovascular Events and Mortality

open access: yesJournal of Epidemiology and Global Health
Background It remains unknown how the patterns of change of social isolation and loneliness are associated with the onset of cardiovascular disease (CVD) and mortality.
Yilin Chen   +7 more
doaj   +1 more source

Reduced expression of the PER2 protein contributes to β1-AA-induced cardiac autophagy rhythm disorders

open access: yesActa Biochimica et Biophysica Sinica
Heart failure may be linked to fluctuations in the rhythm of autophagy in cardiomyocytes throughout the day. Circadian rhythms depend on the regulation of core biological clock proteins, with PER2 playing a crucial role.
Li Pengjia   +8 more
doaj   +1 more source

Sake yeast induces the sleep-promoting effects under the stress-induced acute insomnia in mice

open access: yesScientific Reports, 2021
Sleep deprivation induces adverse effects on the health, productivity, and performance. The individuals who could not get enough sleep temporarily experience the symptoms of an induced acute insomnia. This study investigated the efficacy of sake yeast in
Shohei Nishimon   +2 more
doaj   +1 more source

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