Results 51 to 60 of about 100,006 (157)
Physiology of Circadian Entrainment [PDF]
Physiological Reviews, 2010 Mammalian circadian rhythms are controlled by endogenous biological oscillators, including a master clock located in the hypothalamic suprachiasmatic nuclei (SCN). Since the period of this oscillation is of ∼24 h, to keep synchrony with the environment, circadian rhythms need to be entrained daily by means of Zeitgeber (“time giver”) signals, such as ...
Golombek, Diego Andres +1 more
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Analysis of circadian pattern reveals tissue-specific alternative transcription in leptin signaling pathway [PDF]
, 2007 *Background* It has been previously reported that most mammalian genes display a circadian oscillation in their baseline expression. Consequently, the phase and amplitude of each component of a signal transduction cascade has downstream ...
Jeffrey Gimble +3 more
core +1 more source
A comprehensive review of sleep disordered breathing in people with congenital heart disease
Frontiers in SleepIntroductionSleep disordered breathing (SDB) is known to be a comorbidity associated with congenital heart disease (CHD). This review evaluates the role of sleep disorders as a contributing factor to impairments in cardiovascular health, neurocognitive ...
Kate Maxfield +7 more
doaj +1 more source
Multi-omics profiling reveals rhythmic liver function shaped by meal timing
Nature Communications, 2023 Post-translational modifications (PTMs) couple feed-fast cycles to diurnal rhythms. However, it remains largely uncharacterized whether and how meal timing organizes diurnal rhythms beyond the transcriptome.
Rongfeng Huang +10 more
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Proteomics in Circadian Biology
Journal of Molecular Biology, 2020 The circadian clock is an endogenous molecular timekeeping system that allows organisms to adjust their physiology and behavior to the time of day in an anticipatory fashion. In different organisms, the circadian clock coordinates physiology and metabolism through regulation of gene expression at the transcriptional and post-transcriptional levels ...
Mauvoisin, Daniel, Gachon, Frédéric
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The circadian clock that controls gene expression in Arabidopsis is tissue specific [PDF]
, 2002 The expression of CHALCONE SYNTHASE (CHS) expression is an important control step in the biosynthesis of flavonoids, which are major photoprotectants in plants.
McGrath, Robert B +9 more
core +1 more source
Time of Day and Sleep Deprivation Effects on Risky Decision Making
Clocks & SleepPrevious research has revealed that daily variations in human neurobehavioral functions are driven in part by the endogenous circadian system. The objective of this study was to explore whether there exists a circadian influence on performance regarding ...
Noelia Ruiz-Herrera +5 more
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Social isolation and 59 common health conditions: insights from observational and genetics analyses
BMC MedicineBackground The impacts of social isolation on diverse health conditions and how it contributes to health risks remain unclear. We aimed to investigate the associations of social isolation with 59 health conditions among older adults. Methods Participants
Sizhi Ai +11 more
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Trials, 2022 Background Alcohol use disorder (AUD) is a leading preventable cause of morbidity and mortality, but relapse rates are high even with available treatments.
J. Todd Arnedt +7 more
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Balance equations can buffer noisy and sustained environmental perturbations of circadian clocks [PDF]
, 2010 We present a new approach to understanding how regulatory networks such as circadian clocks might evolve robustness to environmental fluctuations. The approach is in terms of new balance equations that we derive.
David A. Rand +3 more
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