Results 181 to 190 of about 113,418 (363)
Rhythmic Expression of a PER-Reporter in the Malpighian Tubules of Decapitated Drosophila: Evidence for a Brain-Independent Circadian Clock [PDF]
David M. Hege+3 more
openalex +1 more source
Abstract Rigorous and transparent procedures in preclinical epilepsy research studies are important to permit assessing the reproducibility of their findings and derisk their translation into the clinic. The General Pharmacology Working Group of the ILAE/AES Task Force (TASK3‐WG1A) developed common data elements (CDEs) addressing rigor and transparency
Brian D. Klein+11 more
wiley +1 more source
Rest‐activity rhythm phenotypes in adults with epilepsy and intellectual disability
Abstract Objective Rest‐activity rhythms (RARs) are perturbed in many forms of neuropsychiatric illness. In this study, we applied wrist actigraphy to describe RAR perturbations in intellectually disabled adults with epilepsy (“E + ID”), using a cross‐sectional case–control design.
Nandani Adhyapak+3 more
wiley +1 more source
Circadian biology: Clocks for the real world [PDF]
Harriet G. McWatters+2 more
openalex +1 more source
Abstract Objective To leverage RNS® System chronic thalamic EEG recordings to compare ictal and interictal thalamic electrophysiology in idiopathic generalized epilepsy (IGE) and Lennox–Gastaut Syndrome (LGS). Methods As part of ongoing clinical trials in IGE and LGS, intracranial EEG data were acquired from the centromedian nucleus (CM) bilaterally ...
Katie L. Bullinger+3 more
wiley +1 more source
THE MAMMALIAN CIRCADIAN CLOCK: GENE REGULATORY NETWORK AND THEIR COMPUTER ANALYSIS
This paper presents the results of the reconstruction and analysis of gene regulatory network of the circadian clock in mammals. Application of graph theory methods makes it possible to analyze the structure of the gene network and identify the central ...
O. A. Podkolodnaya+2 more
doaj
A new culture method for biochemical studies of the circadian clock
J. Perlman, Jerry F. Feldman
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Abstract Objective The glymphatic system is a critical brain waste‐clearance mechanism that facilitates the removal of metabolic byproducts and maintains neural homeostasis. Its dysfunction has been implicated in various neurological disorders; however, its role in functional (psychogenic nonepileptic) seizures (FS/PNES), a functional neurological ...
Mehrdad Roozbeh+5 more
wiley +1 more source
Molecular Dissection of Two Distinct Actions of Melatonin on the Suprachiasmatic Circadian Clock [PDF]
Chen Liu+6 more
openalex +1 more source