Results 181 to 190 of about 120,096 (334)

Tip60 Is Regulated by Circadian Transcription Factor Clock and Is Involved in Cisplatin Resistance [PDF]

open access: hybrid, 2008
Naoya Miyamoto   +8 more
openalex   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus   +7 more
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat [PDF]

open access: gold, 2018
Panteleimon D. Mavroudis   +3 more
openalex   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

A prospective randomized crossover trial investigating melatonin versus sleep deprivation for sleep induction in nap electroencephalography

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Electroencephalography (EEG) plays a fundamental role in the diagnosis and classification of epilepsy, and inducing sleep during EEG can improve patient cooperation and enhance the detection of epileptiform activity. Despite its importance, there is currently no standardized approach for sleep induction in pediatric EEG recordings ...
Valentina De Giorgis   +11 more
wiley   +1 more source

Predictors of etiology and drug resistance in children with new‐onset focal seizures

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To examine the clinical features of new‐onset focal seizures in children and investigate clinical associations and predictors of underlying etiology and drug resistance. Methods Data were gathered from The Children's Hospital at Westmead admissions for patients aged 1 month to 18 years who presented with new‐onset focal seizures ...
Byoung Chan Lee   +7 more
wiley   +1 more source

The Circadian Clock Protein CRY1 Is a Negative Regulator of HIF-1α [PDF]

open access: gold, 2019
Elitsa Y. Dimova   +14 more
openalex   +1 more source

Home - About - Disclaimer - Privacy