Results 61 to 70 of about 114,755 (253)

Cancer and the Circadian Clock

Cancer Research, 2019
Abstract The circadian clock is a master regulator of mammalian physiology, regulating daily oscillations of crucial biological processes and behaviors. Notably, circadian disruption has recently been identified as an independent risk factor for cancer and classified as a carcinogen.
Ayesha A. Shafi, Karen E. Knudsen
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Circadian Clocks: Translation Lost [PDF]

Current Biology, 2005
One of the big questions in biological rhythms research is how a stable and precise circa-24 hour oscillation is generated on the molecular level. While increasing complexity seemed to be the key, a recent report suggests that circa-24 hour rhythms can be generated by just four molecules incubated in a test tube.
Martha Merrow, Till Roenneberg
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Circadian Rhythms in the CNS and Peripheral Clock Disorders: Role of the Biological Clock in Cardiovascular Diseases

Journal of Pharmacological Sciences, 2007
The cardiovascular diseases are closely related to circadian rhythm, which is under the control of the biological clock. Clock genes show circadian oscillation not only in the suprachiasmatic nucleus but also in peripheral tissues, suggesting the ...
Koji Maemura, Norihiko Takeda, Ryozo Nagai   +2 more
doaj   +1 more source

The Modification of Circadian Clock Components in Soybean During Domestication and Improvement

Frontiers in Genetics, 2020
Agricultural production is greatly dependent on daylength, which is determined by latitude. Living organisms align their physiology to daylength through the circadian clock, which is made up of input sensors, core and peripheral clock components, and ...
Man-Wah Li, Hon-Ming Lam, Hon-Ming Lam
doaj   +1 more source

Contribution of time of day and the circadian clock to the heat stress responsive transcriptome in Arabidopsis. [PDF]

, 2019
In Arabidopsis, a large subset of heat responsive genes exhibits diurnal or circadian oscillations. However, to what extent the dimension of time and/or the circadian clock contribute to heat stress responses remains largely unknown.
Blair, Emily J, Bonnot, Titouan, Hay, Erika, Hummel, Maureen, Marzolino, Jill M, Nagel, Dawn H, Quijada, Ivan A   +6 more
core   +2 more sources

Circadian Clock Proteins and Immunity [PDF]

Immunity, 2014
Immune parameters change with time of day and disruption of circadian rhythms has been linked to inflammatory pathologies. A circadian-clock-controlled immune system might allow an organism to anticipate daily changes in activity and feeding and the associated risk of infection or tissue damage to the host. Responses to bacteria have been shown to vary
Curtis A. M., Bellet M. M., Sassone-Corsi P., O'Neill L. A. J.   +3 more
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Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]

, 2015
Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C, Kwok, Rosanna S, Lam, Vu H   +2 more
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The contribution of circadian clock to the biological processes

Frontiers in Molecular Biosciences
All organisms have various circadian, behavioral, and physiological 24-h periodic rhythms, which are controlled by the circadian clock. The circadian clock controls various behavioral and physiological rhythms.
Beibei Luo, Beibei Luo, Beibei Luo, Jiangyuan Song, Jiangyuan Song, Jiangyuan Song, Jiaqi Zhang, Jiaqi Zhang, Jiaqi Zhang, Jun Han, Jun Han, Jun Han, Xin Zhou, Xin Zhou, Xin Zhou, Lili Chen, Lili Chen, Lili Chen   +17 more
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Mutation of Arabidopsis SPLICEOSOMAL TIMEKEEPER LOCUS1 Causes Circadian Clock Defects [PDF]

, 2012
The circadian clock plays a crucial role in coordinating plant metabolic and physiological functions with predictable environmental variables, such as dusk and dawn, while also modulating responses to biotic and abiotic challenges.
Brown, John WS, Harmer, Stacey L, Jones, Matthew A, McNicol, Jim, Simpson, Craig G, Williams, Brian A   +5 more
core   +1 more source

Glucocorticoids and the circadian clock [PDF]

Journal of Endocrinology, 2008
Glucocorticoids, hormones produced by the adrenal gland cortex, perform numerous functions in body homeostasis and the response of the organism to external stressors. One striking feature of their regulation is a diurnal release pattern, with peak levels linked to the start of the activity phase. This release is under control of the circadian clock, an
openaire   +4 more sources