Results 61 to 70 of about 347,727 (386)
Correlations of single-cell division times with and without periodic forcing [PDF]
Phys. Rev. X 8, 021035 (2018), 2017 Periodic forcing of nonlinear oscillators leads to a large number of dynamic behaviors. The coupling of the cell-cycle to the circadian clock provides a biological realization of such forcing. Using high throughput single-cell microscopy, we have studied the correlations between cell cycle duration in discrete lineages of several different organisms ...
arxiv +1 more source
The choroid plexus is an important circadian clock component
Nature Communications, 2018 Mammalian circadian clocks have a hierarchical organization, governed by the suprachiasmatic nucleus (SCN) in the hypothalamus. The brain itself contains multiple loci that maintain autonomous circadian rhythmicity, but the contribution of the non-SCN ...
J. Myung +10 more
semanticscholar +1 more source
Circadian Clocks: Translation Lost [PDF]
Current Biology, 2005 One of the big questions in biological rhythms research is how a stable and precise circa-24 hour oscillation is generated on the molecular level. While increasing complexity seemed to be the key, a recent report suggests that circa-24 hour rhythms can be generated by just four molecules incubated in a test tube.
Martha Merrow, Till Roenneberg
openaire +2 more sources
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila +11 more
wiley +1 more source
The Modification of Circadian Clock Components in Soybean During Domestication and Improvement
Frontiers in Genetics, 2020 Agricultural production is greatly dependent on daylength, which is determined by latitude. Living organisms align their physiology to daylength through the circadian clock, which is made up of input sensors, core and peripheral clock components, and ...
Man-Wah Li, Hon-Ming Lam, Hon-Ming Lam
doaj +1 more source
Parametric modeling of mechanical effects on circadian oscillators [PDF]
arXiv, 2023 Circadian rhythms are archetypical examples of nonlinear oscillations. While these oscillations are usually attributed to circuits of biochemical interactions among clock genes and proteins, recent experimental studies reveal that they are also affected by the cell's mechanical environment.
arxiv
Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance The molecular clock provides an anticipatory mechanism, allowing organisms to prepare and respond to daily changes in the external environment.
James O. Early +17 more
semanticscholar +1 more source
In vitro and in vivo Phase Changes of the Mouse Circadian Clock by Oxidative Stress
Journal of Circadian Rhythms, 2016 Mammalian circadian rhythms are governed by an endogenous circadian clock system, including the molecular clock works in each cell and tissue. Adaptation of the circadian clock to different environmental stimuli such as light, food, and stress is ...
Yu Tahara +6 more
doaj +1 more source
Enhanced precision of circadian rhythm by output system [PDF]
arXiv, 2022 Circadian rhythms are biological rhythms of approximately 24 h that persist even under constant conditions without environmental daily cues. The molecular circadian clock machinery generates the physiological rhythms, which can be transmitted into the downstream output system. Owing to the stochastic nature of the biochemical reactions, the oscillation
arxiv
Regulation of amyloid-β dynamics and pathology by the circadian clock
Journal of Experimental Medicine, 2018 Nighttime restlessness and daytime drowsiness are common and early symptoms of Alzheimer’s Disease (AD). This symptomology implicates dysfunctional biological timing, yet the role of the circadian system in AD pathogenesis is unknown.
G. Kress +6 more
semanticscholar +1 more source