Results 41 to 50 of about 48,399 (260)

Photoperiodic plasticity in circadian clock neurons in insects

Frontiers in Physiology, 2013
Since Bünning’s observation of circadian rhythms and photoperiodism in the runner bean Phaseolus multiflorus in 1936, many studies have shown that photoperiodism is based on the circadian clock system.
Sakiko eShiga
doaj   +1 more source

Feeding period restriction alters the expression of peripheral circadian rhythm genes without changing body weight in mice. [PDF]

PLoS ONE, 2012
Accumulating evidence suggests that the circadian clock is closely associated with metabolic regulation. However, whether an impaired circadian clock is a direct cause of metabolic dysregulation such as body weight gain is not clearly understood. In this
Hagoon Jang, Gung Lee, Jinuk Kong, Goun Choi, Yoon Jeong Park, Jae Bum Kim   +5 more
doaj   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Circadian synchronization between diet and gut microbiota in modulating host's health

Gut Microbes
Extensive research has established a complex relationship between the host, diet, and gut microbiota. Recent studies highlight the critical role of the host circadian clock in maintaining health.
Jianjun Ma, Yongkang Zhen, Yunan Weng, Jiaqi Lin, Chong Zhang, Yuhong Zhong, Jiaqi Zhou, Mengzhi Wang   +7 more
doaj   +1 more source

Emerging roles for microRNA in the regulation of Drosophila circadian clock

BMC Neuroscience, 2018
Background The circadian clock, which operates within an approximately 24-h period, is closely linked to the survival and fitness of almost all living organisms. The circadian clock is generated through a negative transcription-translation feedback loop.
Yongbo Xue, Yong Zhang
doaj   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

Effect of circadian clock disruption on type 2 diabetes

Frontiers in Physiology
IntroductionType 2 diabetes (T2D) is the predominant form of diabetes mellitus and is among the leading causes of death with an increasing prevalence worldwide. However, the pathological mechanism underlying T2D remains complex and unclear. An increasing
Hong Thuan Tran, Hong Thuan Tran, Takeru Kondo, Amal Ashry, Yunyu Fu, Hiroko Okawa, Chenphop Sawangmake, Chenphop Sawangmake, Chenphop Sawangmake, Hiroshi Egusa   +9 more
doaj   +1 more source

Feeding and circadian clocks [PDF]

Reproduction Nutrition Development, 2006
The mammalian genome encodes at least a dozen of genes directly involved in the regulation of the feedback loops constituting the circadian clock. The circadian system is built up on a multitude of oscillators organized according to a hierarchical model in which neurons of the suprachiasmatic nuclei of the hypothalamus may drive the central circadian ...
Lissia, Pardini, Bertrand, Kaeffer
openaire   +2 more sources

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Ror homolog nhr-23 is essential for both developmental clock and circadian clock in C. elegans

Communications Biology
Animals have internal clocks that generate biological rhythms. In mammals, clock genes such as Period form the circadian clock to generate approximately 24-h biological rhythms. In C. elegans, the clock gene homologs constitute the “developmental clock”,
Shingo Hiroki, Hikari Yoshitane
doaj   +1 more source