Results 51 to 60 of about 256,062 (252)

Adult Circadian behavior in Drosophila requires developmental expression of cycle, but not period [PDF]

, 2011
Circadian clocks have evolved as internal time keeping mechanisms that allow anticipation of daily environmental changes and organization of a daily program of physiological and behavioral rhythms.
Bonilla Gloribel, Goda Tadahiro, Tadahiro Goda, Neethi Varadaraja Rao, Herman Wijnen, Wijnen Herman, Currie, Jake, Kim Min-Ho, Karolina Mirowska, Rao Neethi Varadaraja, Gloribel Bonilla, Goda, Tadahiro, Wijnen, Herman, Rao, Neethi Varadaraja, Mirowska, Karolina, Kim, Min-Ho, Bonilla, Gloribel, Bonilla Herman, Min-Ho Kim, Currie Jake, Mirowska Karolina, Jake Currie   +21 more
core   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Zwitterionic Polymer Coating Enabled Chronic Dopamine Sensing and Electrophysiology Recording in Free‐Moving Mice

Advanced Healthcare Materials, EarlyView.
Application of a zwitterionic poly(sulfobetaine methacrylate) (PSB) coating to microelectrode arrays and Ag/AgCl reference electrodes effectively inhibits biofouling and structural degradation. This strategy successfully enables simultaneous, long‐term electrophysiological recording and dopamine sensing in freely behaving mice, facilitating ...
Bingchen Wu, Cort Thompson, Thomas Deakin, Yan Xu, Colleen A. McClung, Xinyan Tracy Cui   +5 more
wiley   +1 more source

Period 2: A Regulator of Multiple Tissue-Specific Circadian Functions

Frontiers in Molecular Neuroscience, 2021
The zebrafish represents a powerful model for exploring how light regulates the circadian clock due to the direct light sensitivity of its peripheral clocks, a property that is retained even in organ cultures as well as zebrafish-derived cell lines ...
Gennaro Ruggiero, Gennaro Ruggiero, Zohar Ben-Moshe Livne, Yair Wexler, Nathalie Geyer, Daniela Vallone, Yoav Gothilf, Yoav Gothilf, Nicholas S. Foulkes   +8 more
doaj   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

Advanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

Circadian synchronization between diet and gut microbiota in modulating host's health

Gut Microbes
Extensive research has established a complex relationship between the host, diet, and gut microbiota. Recent studies highlight the critical role of the host circadian clock in maintaining health.
Jianjun Ma, Yongkang Zhen, Yunan Weng, Jiaqi Lin, Chong Zhang, Yuhong Zhong, Jiaqi Zhou, Mengzhi Wang   +7 more
doaj   +1 more source

Photoperiodic plasticity in circadian clock neurons in insects

Frontiers in Physiology, 2013
Since Bünning’s observation of circadian rhythms and photoperiodism in the runner bean Phaseolus multiflorus in 1936, many studies have shown that photoperiodism is based on the circadian clock system.
Sakiko eShiga
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Effect of circadian clock disruption on type 2 diabetes

Frontiers in Physiology
IntroductionType 2 diabetes (T2D) is the predominant form of diabetes mellitus and is among the leading causes of death with an increasing prevalence worldwide. However, the pathological mechanism underlying T2D remains complex and unclear. An increasing
Hong Thuan Tran, Hong Thuan Tran, Takeru Kondo, Amal Ashry, Yunyu Fu, Hiroko Okawa, Chenphop Sawangmake, Chenphop Sawangmake, Chenphop Sawangmake, Hiroshi Egusa   +9 more
doaj   +1 more source

Evidence for widespread dysregulation of circadian clock progression in human cancer [PDF]

PeerJ, 2018
The ubiquitous daily rhythms in mammalian physiology are guided by progression of the circadian clock. In mice, systemic disruption of the clock can promote tumor growth. In vitro, multiple oncogenes can disrupt the clock.
Jarrod Shilts, Guanhua Chen, Jacob J. Hughey   +2 more
doaj   +2 more sources