Results 31 to 40 of about 372,746 (304)
Circadian clock—A promising scientific target in oral science
Frontiers in Physiology, 2022 The oral and maxillofacial organs play vital roles in chewing, maintaining facial beauty, and speaking. Almost all physiological processes display circadian rhythms that are driven by the circadian clock, allowing organisms to adapt to the changing ...
Guangxia Feng +16 more
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Molecular mechanism of the repressive phase of the mammalian circadian clock
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The circadian clock mechanism is a daily rhythmic activation of circadian gene transcription by the CLOCK–BMAL1 heterodimer and repression by CRYs (CRY1 and CRY2) and PERs (PER1 and PER2).
Xuemei Cao +4 more
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Nutrients, 2023 Rhythmicity is a fundamental characteristic of every living organism [...]
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The circadian clock in mammals [PDF]
The Journal of Headache and Pain, 2000 The basic physiological and anatomical basis for circadian rhythms in mammalian behaviour and physiology is introduced. The pathways involved in photic entrainment of the circadian clock are discussed in relation of new findings that identify the molecules that are involved in signalling between the environment and the clock.
ZORDAN, MAURO AGOSTINO, KYRIACOU C. P.
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Neurodegeneration and the Circadian Clock [PDF]
Frontiers in Aging Neuroscience, 2017 Despite varied etiologies and symptoms, several neurodegenerative diseases-specifically, Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HDs)-share the common feature of abnormal circadian rhythms, such as those in behavior (e.g., disrupted sleep/wake cycles), physiological processes (e.g., diminished hormone release) and biochemical ...
Hood, Suzanne, Amir, Shimon
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Molecular Links between the Circadian Clock and the Cell Cycle.
Journal of Molecular Biology, 2020 Circadian control of cell division is well established in diverse organisms. Recent single cell studies on mouse fibroblasts have shown that the circadian clock and cell cycle systems are robustly phase-coupled in a bidirectional manner. In healthy cells,
Elham Farshadi +2 more
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Circadian Rhythm, Clock Genes and Hypertension: Recent Advances in Hypertension
HYPERTENSION, 2021 Accumulating evidence suggests that the molecular circadian clock is crucial in blood pressure (BP) control. Circadian rhythms are controlled by the central clock, which resides in the suprachiasmatic nucleus of the hypothalamus and peripheral clocks ...
Hannah M. Costello, Michelle L. Gumz
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Silybin A enhances circadian clock by targeting CRY1 and disrupting its interaction with CLOCK
Pharmacological Research - Modern Chinese Medicine, 2022 Circadian clock governs a large array of physiological and metabolic functions. The amplitude decline of circadian rhythm is associated with various chronic diseases. However, few clock enhancing-molecules are known. CRY1 is one of the main components of
Weijie Bian +4 more
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Molecular Interactions Between Components of the Circadian Clock and the Immune System
Journal of Molecular Biology, 2020 The immune system is under control of the circadian clock. Many of the circadian rhythms observed in the immune system originate in direct interactions between components of the circadian clock and components of the immune system.
S. Hergenhan +2 more
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Circadian Clocks and Pregnancy [PDF]
Frontiers in Endocrinology, 2014 The recognition that 24-h rhythmic processes (“circadian”) underlie many endocrine functions has added a fascinating new temporal dimension to our appreciation of their complexity. Research from various laboratories has revealed circadian gene expression in multiple tissues in the reproductive system of non-pregnant and pregnant mammals.
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