Results 71 to 80 of about 114,755 (253)
The circadian clock goes genomic [PDF]
Genome Biology, 2013 Large-scale biology among plant species, as well as comparative genomics of circadian clock architecture and clock-regulated output processes, have greatly advanced our understanding of the endogenous timing system in plants.
Staiger, Dorothee +3 more
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In vitro and in vivo Phase Changes of the Mouse Circadian Clock by Oxidative Stress
Journal of Circadian Rhythms, 2016 Mammalian circadian rhythms are governed by an endogenous circadian clock system, including the molecular clock works in each cell and tissue. Adaptation of the circadian clock to different environmental stimuli such as light, food, and stress is ...
Yu Tahara +6 more
doaj +1 more source
Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. [PDF]
PLoS ONE, 2010 Cell proliferation in all rapidly renewing mammalian tissues follows a circadian rhythm that is often disrupted in advanced-stage tumors. Epidemiologic studies have revealed a clear link between disruption of circadian rhythms and cancer development in ...
Susie Lee +4 more
doaj +1 more source
Rhythms of Locomotion Expressed by Limulus polyphemus, the American Horseshoe Crab: II. Relationship to Circadian Rhythms of Visual Sensitivity [PDF]
, 2008 In the laboratory, horseshoe crabs express a circadian rhythm of visual sensitivity as well as daily and circatidal rhythms of locomotion. The major goal of this investigation was to determine whether the circadian clock underlying changes in visual ...
Bedford, Lisa +2 more
core +3 more sources
The circadian clock and behavior
Behavioural Brain Research, 2001 Temporal organization is a fundamental feature of all living systems. Timing is essential for development, growth and differentiation and in the mature organism, it is essential to maintain normal physiology and behavior. The biological entity that permits an organism's day/night organization is the circadian system.
Urs Albrecht, Henrik Oster
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A scenario of unhealthy life cycle: The role of circadian rhythms in health
Aging MedicineCircadian rhythms are oscillations in physiology and behavior caused by the circadian regulator. Cryptochromes, Periods, and Bmal1 are circadian clock genes that have been linked to aging and cancer.
Manasa Chandramouli +2 more
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Circadian clock control of Nox4 and reactive oxygen species in the vasculature. [PDF]
PLoS ONE, 2013 Recent studies have shown that circadian clock disruption is associated with pathological remodeling in the arterial structure and vascular stiffness.
Ciprian B Anea +10 more
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From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Circadian Clocks, Stress, and Immunity [PDF]
Frontiers in Endocrinology, 2016 In mammals, molecular circadian clocks are present in most cells of the body, and this circadian network plays an important role in synchronizing physiological processes and behaviors to the appropriate time of day. The hypothalamic-pituitary-adrenal endocrine axis regulates the response to acute and chronic stress, acting through its final effectors -
Dumbell, R, Matveeva, O, Oster, H
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Plants, 2023 The circadian clock, an endogenous timing system, exists in nearly all organisms on Earth. The plant circadian clock has been found to be intricately linked with various essential biological activities. Extensive studies of the plant circadian clock have
Xingwei Wang, Yanfei Hu, Wei Wang
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