Results 81 to 90 of about 402,265 (407)
Plants, 2023 The circadian clock, an endogenous timing system, exists in nearly all organisms on Earth. The plant circadian clock has been found to be intricately linked with various essential biological activities. Extensive studies of the plant circadian clock have
Xingwei Wang, Yanfei Hu, Wei Wang
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Quantitative analysis of regulatory flexibility under changing environmental conditions [PDF]
, 2010 The circadian clock controls 24-h rhythms in many biological processes, allowing appropriate timing of biological rhythms relative to dawn and dusk. Known clock circuits include multiple, interlocked feedback loops.
Adrian W Thomson +12 more
core +4 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Circadian clocks control various aspects of physiology. The circadian control of the response of T cells to antigen presentation, which is at the core of the specific immune response to pathogens, has remained unclear.
C. Nobis +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Circadian clock control of Nox4 and reactive oxygen species in the vasculature. [PDF]
PLoS ONE, 2013 Recent studies have shown that circadian clock disruption is associated with pathological remodeling in the arterial structure and vascular stiffness.
Ciprian B Anea +10 more
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Period 2: A Regulator of Multiple Tissue-Specific Circadian Functions
Frontiers in Molecular Neuroscience, 2021 The zebrafish represents a powerful model for exploring how light regulates the circadian clock due to the direct light sensitivity of its peripheral clocks, a property that is retained even in organ cultures as well as zebrafish-derived cell lines ...
Gennaro Ruggiero +8 more
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Circadian Clocks, Stress, and Immunity [PDF]
Frontiers in Endocrinology, 2016 In mammals, molecular circadian clocks are present in most cells of the body, and this circadian network plays an important role in synchronizing physiological processes and behaviors to the appropriate time of day. The hypothalamic-pituitary-adrenal endocrine axis regulates the response to acute and chronic stress, acting through its final effectors -
Dumbell, R, Matveeva, O, Oster, H
openaire +3 more sources
Cell-autonomous regulation of astrocyte activation by the circadian clock protein BMAL1
bioRxiv, 2018 Circadian clock dysfunction is a common symptom of aging and neurodegenerative diseases, though its impact on brain health is poorly understood. Astrocyte activation occurs in response to diverse insults, and plays a critical role in brain health and ...
Brian V. Lananna +15 more
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Molecular Oncology, EarlyView.This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain +3 more
wiley +1 more source
Heterogeneous expression of the core circadian clock proteins among neuronal cell types in mouse retina. [PDF]
PLoS ONE, 2012 Circadian rhythms in metabolism, physiology, and behavior originate from cell-autonomous circadian clocks located in many organs and structures throughout the body and that share a common molecular mechanism based on the clock genes and their protein ...
Xiaoqin Liu +2 more
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