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The role of circadian gene CLOCK in cancer
Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchCircadian Locomotor Output Cycles Kaput (CLOCK) is one of the circadian clock genes and is considered to be a fundamental regulatory gene in the circadian rhythm, responsible for mediating several biological processes. Therefore, abnormal expression of CLOCK affects its role in the circadian clock and its more general function as a direct regulator of ...
Nasot, Rashed +4 more
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Hypothalamic Circadian Organization in Birds. II. Clock Gene Expression
Chronobiology International, 2003While the site of the major circadian pacemaker in mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus, is very well characterized, little is known about hypothalamic circadian organization in birds. This paper reviews recent findings on clock gene expression in the hypothalamus of several bird species focusing on circadian pPer2 expression ...
Abraham, U. +2 more
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From circadian rhythms to clock genes in depression
International Clinical Psychopharmacology, 2007Depression, particularly unipolar depression, has often been linked to circadian (i.e. approximately 24-h) rhythm abnormalities. The observation that many diverse rhythms are disrupted in depressed patients indicates that such disturbances are not unique to specific rhythms, but instead are of a more central origin (i.e.
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Circadian Clock Genes and Mood Disorders
2016Circadian clocks are driven by signals from the wild in order to match the functions of an organism with the passage of the solar day and to reset their intrinsic phase relative to external local time. A key function of the circadian clocks allows individuals to anticipate routine environmental conditions and to adjust their behaviors to the change of ...
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?Circadian clock? directs the expression of plant genes
Plant Molecular Biology, 1993Plants as well as animals can tell the time without the aid of wrist watches [53]. This fact is due to the universal phenomenon of endogenous clocks. Depending on the natural environmental periodicities organisms display a range of biological rhythms. A rhythm is defined as a selfsustaining repeating fluctuation pattern.
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Circadian clock genes in insects
2017This thesis focuses on molecular characterization of circadian clock genes in insects. It explores genetic diversity of circadian clock genes by molecular characterization of several insect species including two dipteran flies (Musca domestica and Drosophila melanogaster), two cockroach species representing ancestral insects, and the linden bug ...
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The circadian system: circuits-cells-clock genes
Cell and Tissue Research, 2002Horst-Werner, Korf, Jörg H, Stehle
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Circadian clock genes in the circadian clock and photoperiodic timer in Pyrrhocoris apterus
2019This thesis focuses on the circadian clock genes and their involvement in the photoperiodic time measurement in the linden bug, Pyrrhocoris apterus. Application of the molecular biology methods enabled us to propose the architecture of circadian clockwork.
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