Results 61 to 70 of about 67,567 (286)

Ror homolog nhr-23 is essential for both developmental clock and circadian clock in C. elegans

Communications Biology
Animals have internal clocks that generate biological rhythms. In mammals, clock genes such as Period form the circadian clock to generate approximately 24-h biological rhythms. In C. elegans, the clock gene homologs constitute the “developmental clock”,
Shingo Hiroki, Hikari Yoshitane
doaj   +1 more source

The Circadian Clock-controlled Transcriptome of Developing Soybean Seeds

The Plant Genome, 2010
A number of metabolic and physiological processes in plants are controlled by the circadian clock, which enables a plant to anticipate daily changes in the environment.
Karen A. Hudson
doaj   +1 more source

Network balance via CRY signalling controls the Arabidopsis circadian clock over ambient temperatures [PDF]

, 2013
Circadian clocks exhibit ‘temperature compensation', meaning that they show only small changes in period over a broad temperature range. Several clock genes have been implicated in the temperature-dependent control of period in Arabidopsis.
Costa, Maria J. (Maria João), Domijan, Mirela, Finkenstädt, Bärbel, Foreman, Julia, Gould, Peter D., Griffiths, Jayne, Hall, Anthony J. W., Halliday, Karen J., MacGregor, Dana, Millar, A. J. (Andrew J.), Penfield, Steven, Rand, D. A. (David A.), Rose, Ken, Ugarte, Nicolas   +13 more
core   +5 more sources

Clock Genes Show Circadian Rhythms in Salivary Glands [PDF]

Journal of Dental Research, 2012
Circadian rhythms are endogenous self-sustained oscillations with 24-hour periods that regulate diverse physiological and metabolic processes through complex gene regulation by “clock” transcription factors. The oral cavity is bathed by saliva, and its amount and content are modified within regular daily intervals.
L, Zheng, Y J, Seon, J, McHugh, S, Papagerakis, P, Papagerakis   +4 more
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Heritable gene expression variability and stochasticity govern clonal heterogeneity in circadian period.

PLoS Biology, 2020
A ubiquitous feature of the circadian clock across life forms is its organization as a network of cellular oscillators, with individual cellular oscillators within the network often exhibiting considerable heterogeneity in their intrinsic periods.
K L Nikhil, Sandra Korge, Achim Kramer
doaj   +1 more source

A Bioinformatics Approach [PDF]

, 2015
By regulating the timing of cellular processes, the circadian clock provides a way to adapt physiology and behaviour to the geophysical time. In mammals, a light-entrainable master clock located in the suprachiasmatic nucleus (SCN) controls peripheral ...
Abreu, Monica, Childs, Liam, Fuhr, Luise, Herzel, Hanspeter, Lehmann, Robert, Leser, Ulf, Relógio, Angela, Thomas, Philippe   +7 more
core   +1 more source

Circadian disruption, clock genes, and metabolic health

Journal of Clinical Investigation
A growing body of research has identified circadian-rhythm disruption as a risk factor for metabolic health. However, the underlying biological basis remains complex, and complete molecular mechanisms are unknown. There is emerging evidence from animal and human research to suggest that the expression of core circadian genes, such as circadian ...
Schrader, Lauren A., Ronnekleiv-Kelly, Sean M., Hogenesch, John B., Bradfield, Christopher A., Malecki, Kristen M.C.   +4 more
openaire   +2 more sources

Diapause: Circadian Clock Genes Are at It Again [PDF]

Current Biology, 2019
Understanding how insects synchronize their annual life cycle to local conditions remains poorly understood. A new study integrates a QTL investigation with population genomic analyses in a Lepidopteran to show that, yet again, allelic variation in circadian clock genes has a role in seasonal timing of diapause.
Karl, Gotthard, Christopher W, Wheat
openaire   +2 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source