Results 71 to 80 of about 67,567 (286)

Comparative analysis of circadian clock genes in insects [PDF]

open access: yesInsect Molecular Biology, 2008
Summary After a slow start, the comparative analysis of clock genes in insects has developed into a mature area of study in recent years. Brain transplant or surgical interventions in larger insects defined much of the early work in this area, before the cloning of clock genes became possible.
SANDRELLI, FEDERICA   +3 more
openaire   +4 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Molecular mechanisms in mood regulation involving the circadian clock [PDF]

open access: yes, 2017
The circadian system coordinates activities and functions in cells and tissues in order to optimize body functions in anticipation to daily changes in the environment.
Albrecht, Urs
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Molecular characterization of the circadian clock in paediatric leukaemia patients: a prospective study protocol

open access: yesBMC Pediatrics, 2023
Background In many organisms, including humans, the timing of cellular processes is regulated by the circadian clock. At the molecular level the core-clock consists of transcriptional-translational-feedback loops including several genes such as BMAL1 ...
Marius Ludwig   +4 more
doaj   +1 more source

Detection of diurnal variation of tomato transcriptome through the molecular timetable method in a sunlight-type plant factory [PDF]

open access: yes, 2016
The timing of measurement during plant growth is important because many genes are expressed periodically and orchestrate physiological events. Their periodicity is generated by environmental fluctuations as external factors and the circadian clock as the
Fukuda, Hirokazu   +5 more
core   +1 more source

The brain, circadian rhythms, and clock genes

open access: yesBMJ, 1998
Every day we experience profound changes in our mental and physical condition as body and brain alternate between states of high activity during the waking day and recuperation, rest, and repair during night time sleep. These cycles are not a passive response to the world around us: they are pre-adapted, driven by an internal clock.
openaire   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration [PDF]

open access: yes, 2013
Brain aging is associated with diminished circadian clock output and decreased expression of the core clock proteins, which regulate many aspects of cellular biochemistry and metabolism.
Adam Q. Bauer   +25 more
core   +2 more sources

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

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