Results 121 to 130 of about 42,531 (357)
Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]
, 2015 Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C +2 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim PREDICT‐5FU aimed to document 5‐fluorouracil (5FU) exposure in a cancer population and to evaluate the feasibility of 5FU and capecitabine therapeutic drug monitoring (TDM) in patients receiving standard doses and schedules. Methods Multicentre, prospective, observational single‐arm study.
Sarah Glewis +12 more
wiley +1 more source
What season suits you best? Seasonal light changes and cyanobacterial competition [PDF]
, 2015 Nearly all living organisms, including some bacterial species, exhibit biological processes with a period of about 24 h called circadian (from the Latin circa, about and dies, day) rhythms.
Cascallares, Maria Guadalupe +1 more
core +1 more source
Medications, epilepsy and climate change: Added layers of complexity
British Journal of Clinical Pharmacology, EarlyView.Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi +2 more
wiley +1 more source
Robustness from flexibility in the fungal circadian clock [PDF]
, 2010 Background Robustness is a central property of living systems, enabling function to be maintained against environmental perturbations. A key challenge is to identify the structures in biological circuits that confer system-level properties such as ...
Akman, Ozgur E. +3 more
core +4 more sources
Dynamic Compression Improves Chondrogenesis in the Tissue Engineered Model of Cartilage
Biotechnology and Bioengineering, EarlyView.ABSTRACT Hyaline cartilage is a dense avascular tissue with low regenerative potential, present at the ends of the diarthrodial joints and in the cartilage growth plate. Skeletal diseases often result from extracellular changes in this tissue; however, studies of these are hindered by the tissue complexity, the difficulty in obtaining human material ...
Marc V. Farcasanu +8 more
wiley +1 more source
Synchrony of plant cellular circadian clocks with heterogeneous properties under light/dark cycles
Scientific Reports, 2017 Individual cells in a plant can work independently as circadian clocks, and their properties are the basis of various circadian phenomena. The behaviour of individual cellular clocks in Lemna gibba was orderly under 24-h light/dark cycles despite their ...
Masaaki Okada +3 more
doaj +1 more source
Bio-Protocol, 2017 Circadian rhythms are biological processes displaying an endogenous oscillation with a period of ~24 h. They allow organisms to anticipate and get prepared for the environmental changes caused mainly by the rotation of Earth. Circadian rhythms are driven
Qiang Chen +3 more
doaj +1 more source
A Colorful Model of the Circadian Clock [PDF]
Cell, 2006 The migration of the colorful monarch butterfly provides biologists with a unique model system with which to study the cellular and molecular mechanisms underlying a sophisticated circadian clock. The monarch circadian clock is involved in the induction of the migratory state and navigation over long distances, using the sun as a compass.
openaire +4 more sources
Canadian Journal of Statistics, EarlyView.Abstract Modern longitudinal data from wearable devices consist of biological signals at high‐frequency time points. Distributed statistical methods have emerged as a powerful tool to overcome the computational burden of estimation and inference with large data, but methodology for distributed functional regression remains limited.
Cole Manschot, Emily C. Hector
wiley +1 more source