Results 101 to 110 of about 5,427 (264)

The Circadian Clock, Reward, and Memory [PDF]

Frontiers in Molecular Neuroscience, 2011
During our daily activities, we experience variations in our cognitive performance, which is often accompanied by cravings for small rewards, such as consuming coffee or chocolate. This indicates that the time of day, cognitive performance, and reward may be related to one another.
openaire   +5 more sources

Behavioral, electrophysiological, and cerebral correlates of vulnerability to sleep loss : the impact of sleep pressure, circadian phase, and a PER3 polymorphism [PDF]

, 2014
Behavioral, electrophysiological, and cerebral correlates of vulnerability to sleep loss: The impact of sleep pressure, circadian phase, and a PER3 polymorphism.
Maire, Micheline
core   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures [PDF]

, 2014
Sleep and circadian rhythms are intrinsically linked, with several sleep traits, including sleep timing and duration, influenced by both sleep homeostasis and the circadian phase.
Lester, Kathryn, Lester, KJ, Archer, Simon, Archer, SN, Gregory, Alice M, Lester, Kathryn J., Barclay, Nicola L., Gregory, Alice, Nolan, Patrick M., Nolan, PM, Nolan, Patrick, Parsons, Michael J., Eley, Thalia C, Archer, Simon N., Barclay, Nicola, Gregory, AM, Patrick M Nolan (11641339), Barclay, Nicola L, Eley, Thalia C., Nolan, Patrick M, Archer, Simon N, Parsons, Michael J, Kathryn Lester (4462210), Nicola L Barclay (16221641), Parsons, Michael, Thalia C Eley (13615696), Parsons, MJ, Eley, Thalia, Simon N Archer (16221644), Alice M Gregory (11992776), Lester, Kathryn J, Michael J Parsons (16221638), Gregory, Alice M., Eley, TC, Barclay, NL   +34 more
core   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Time to Eat Your Vegetables: The Role of Circadian Clocks in Insect Herbivory

Insects
Insects exhibit a range of ecological relationships with plants, including pollination, seed dispersal, parasitism, predation, and herbivory. Interactions between insects and plants are shaped by internal daily timekeeping systems in both sets of ...
Lena Smith, Connor J. Tyler, Shubhangi Mahajan, Haruko Okamoto, Herman Wijnen   +4 more
doaj   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Non-alcoholic Fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms. [PDF]

, 2014
Emerging evidence suggests that maternal obesity (MO) predisposes offspring to obesity and the recently described non-alcoholic fatty pancreas disease (NAFPD) but involved mechanisms remain unclear.
Mouralidarane Angelina, Chiara Saracino, Lucilla Poston (200809), Francesca Rappa, Ruma Saraswati, Fusai, Giuseppe, Paul D. Taylor (200813), Pazienza Valerio, Junpei Soeda, Carter, Rebeca, Jude A Oben, Angelina Mouralidarane (540950), Saraswati Ruma, Paul D Taylor, Mouralidarane, Angelina, Oben, JA, Saraswati, R, Fusai Giuseppe, Marco Novelli, Carter, R, Poston Lucilla, Marco Novelli (540954), Giuseppe Fusai (540955), Shuvra Ray (540951), Soeda, Junpei, Soeda, J, Pombo, J, Mouralidarane, A, Rappa, F, Ruma Saraswati (540953), Pazienza, Valerio, Novelli, Marco, Taylor Paul D., Joaquim Pombo (540952), Carter Rebeca, Saracino, C, Manlio Vinciguerra (287299), Saraswati, Ruma, Novelli, M, Oben, Jude A, Angelina Mouralidarane, Pombo, Joaquim, Fusai, G, RAPPA, Francesca, Saracino, Chiara, Novelli Marco, Rappa Francesca, Lucilla Poston, Francesca Rappa (55683), Manlio Vinciguerra, Rebeca Carter, Saracino Chiara, Poston, Lucilla; id_orcid, Pazienza, V, Vinciguerra, M, Joaquim Pombo, Rebeca Carter (540949), Ray Shuvra, Vinciguerra, Manlio, Vinciguerra, M. Oben J.A., Junpei Soeda (453348), Valerio Pazienza, Poston, L, Vinciguerra Manlio, Ray, S, Jude A. Oben (453352), Taylor, PD, Soeda Junpei, Giuseppe Fusai, Oben Jude A., Pombo Joaquim, Valerio Pazienza (174196), Taylor, Paul D; id_orcid, Chiara Saracino (540956), Ray, Shuvra, Shuvra Ray   +75 more
core   +1 more source

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

Advanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari, Natalie Ness, Julieta Acosta, Marco Brancaccio   +3 more
wiley   +1 more source