Results 81 to 90 of about 5,427 (264)

A cellular model for human daily behaviour [PDF]

open access: yes, 2010
All the biochemical, physiological or behavioural processes whose period is about 24 hours possess a circadian rhythm. In mammals circadian rhythms control almost all aspects of human daily behaviour and physiology.
Pagani, Lucia
core   +1 more source

Microfluidic Engineering of Chitosan‐Coated Nanoemulsions for Controlled Release and Stability in Space Pharmaceutics

open access: yesAdvanced Materials Technologies, EarlyView.
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale   +3 more
wiley   +1 more source

An antagonistic role of clock genes and lima1 in kidney regeneration

open access: yesCommunications Biology
The circadian clock genes are known important for kidney development, maturation and physiological functions. However, whether and how they play a role in renal regeneration remain elusive.
Xian He   +4 more
doaj   +1 more source

Rhythms of metabolism in adipose tissue and mitochondria

open access: yesNeurobiology of Sleep and Circadian Rhythms, 2018
Circadian clocks synchronize the daily functions of organisms with environmental cues like light-dark cycles and feeding rhythms. The master clock in the suprachiasmatic nucleus in the hypothalamus of the brain and the many clocks in the periphery are ...
Yasemin Onder, Carla B. Green
doaj   +1 more source

Towards an Understanding of Circatidal Clocks

open access: yesFrontiers in Physiology, 2022
Circadian clocks are an intrinsic element of life that orchestrate appropriately timed daily physiological and behavioural rhythms entrained to the solar cycle, thereby conferring increased fitness.
Alberto Rock   +2 more
doaj   +1 more source

Analysis of circadian pattern reveals tissue-specific alternative transcription in leptin signaling pathway

open access: yes, 2007
*Background* It has been previously reported that most mammalian genes display a circadian oscillation in their baseline expression. Consequently, the phase and amplitude of each component of a signal transduction cascade has downstream ...
Jeffrey Gimble   +3 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Phenotypic and genotypic profiling of efflux pump-mediated multidrug resistance in Pseudomonas aeruginosa clinical isolates

open access: yesИнфекция и иммунитет
Pseudomonas aeruginosa is an opportunistic pathogen of major global health concern, due to its increasing multidrug resistance (MDR). One of the principal mechanism contributing to its MDR phenotype is the overexpression of efflux pump systems ...
A. Ullah   +6 more
doaj   +1 more source

Physiological links of circadian clock and biological clock of aging

open access: yesProtein & Cell, 2017
Circadian rhythms orchestrate biochemical and physiological processes in living organisms to respond the day/night cycle. In mammals, nearly all cells hold self-sustained circadian clocks meanwhile couple the intrinsic rhythms to systemic changes in a ...
Fang Liu, Hung-Chun Chang
doaj   +1 more source

Glucocorticoids and the circadian clock [PDF]

open access: yesJournal of Endocrinology, 2008
Glucocorticoids, hormones produced by the adrenal gland cortex, perform numerous functions in body homeostasis and the response of the organism to external stressors. One striking feature of their regulation is a diurnal release pattern, with peak levels linked to the start of the activity phase. This release is under control of the circadian clock, an
openaire   +3 more sources

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