Results 61 to 70 of about 5,427 (264)

Circadian Clocks, Stress, and Immunity [PDF]

Frontiers in Endocrinology, 2016
In mammals, molecular circadian clocks are present in most cells of the body, and this circadian network plays an important role in synchronizing physiological processes and behaviors to the appropriate time of day. The hypothalamic-pituitary-adrenal endocrine axis regulates the response to acute and chronic stress, acting through its final effectors -
Dumbell, R, Matveeva, O, Oster, H
openaire   +3 more sources

A miR-219-5p-bmal1b negative feedback loop contributes to circadian regulation in zebrafish

Communications Biology
MicroRNAs post-transcriptionally regulate gene expression and contribute to numerous life processes, including circadian rhythms. However, whether miRNAs contribute to zebrafish circadian regulation has not yet been investigated.
Lianxin Wu, Meng Zhao, Xifeng Chen, Han Wang   +3 more
doaj   +1 more source

Intestinal Stem Cells Exhibit Conditional Circadian Clock Function

Stem Cell Reports, 2018
Summary: The circadian clock is a molecular pacemaker that produces 24-hr physiological cycles known as circadian rhythms. How the clock regulates stem cells is an emerging area of research with many outstanding questions.
Kathyani Parasram, Nathaniel Bernardon, Maha Hammoud, Hanna Chang, Li He, Norbert Perrimon, Phillip Karpowicz   +6 more
doaj   +1 more source

Circadian Chimeric Mice Reveal an Interplay Between the Suprachiasmatic Nucleus and Local Brain Clocks in the Control of Sleep and Memory

Frontiers in Neuroscience, 2021
Sleep is regulated by circadian and homeostatic processes. Whereas the suprachiasmatic nucleus (SCN) is viewed as the principal mediator of circadian control, the contributions of sub-ordinate local circadian clocks distributed across the brain are ...
Elizabeth Susan Maywood, Johanna Elizabeth Chesham, Raphaelle Winsky-Sommerer, Nicola Jane Smyllie, Michael Harvey Hastings   +4 more
doaj   +1 more source

Clockwork green – the circadian oscillator in Arabidopsis

, 2006
Schöning JC, Streitner C, Staiger D. Clockwork green – the circadian oscillator in Arabidopsis. Biological Rhythm Research. 2006;37(4):335-352.Although rhythmic leaf movement in a higher plant was the first physiological process recognised to be under ...
Schöning, Jan C., Staiger, Dorothee, Streitner, Corinna   +2 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Endogenous melatonin promotes rhythmic recruitment of neutrophils toward an injury in zebrafish

Scientific Reports, 2017
Neutrophil recruitment to injured tissue appears to be an evolutionarily conserved strategy for organisms to fight against exogenous insults. Recent studies have shown rhythmic migration of neutrophils and several factors, including melatonin, have been ...
Da-long Ren, Cheng Ji, Xiao-Bo Wang, Han Wang, Bing Hu   +4 more
doaj   +1 more source

Circadian and Circalunar Clock Interactions in a Marine Annelid

Cell Reports, 2013
Life is controlled by multiple rhythms. Although the interaction of the daily (circadian) clock with environmental stimuli, such as light, is well documented, its relationship to endogenous clocks with other periods is little understood.
Juliane Zantke, Tomoko Ishikawa-Fujiwara, Enrique Arboleda, Claudia Lohs, Katharina Schipany, Natalia Hallay, Andrew D. Straw, Takeshi Todo, Kristin Tessmar-Raible   +8 more
doaj   +1 more source

Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice

Medicina, 2022
Background and Objectives: The antidiabetic agent metformin is known to activate AMP-activated protein kinase (AMPK) in various tissues. Because AMPK can modulate intracellular circadian clocks through regulating the stability of clock components, a ...
Nazmul Hasan, Koki Sugimoto, Koki Yamada, Jun-ichi Morishige, Kentaro Ushijima, Akio Fujimura, Naoto Nagata, Hitoshi Ando   +7 more
doaj   +1 more source

Human Circadian Phase Estimation from Signals Collected in Ambulatory Conditions Using an Autoregressive Model [PDF]

, 2013
Phase estimation of the human circadian rhythm is a topic that has been explored using various modeling approaches. The current models range from physiological to mathematical, all attempting to estimate the circadian phase from different physiological ...
Gil, Enrique A, Møst, Els I S, Beersma, Domien G M, Beersma, Domien G. M., Møst, Els I.S., Aubert, Xavier L, Gil, Enrique A.,, Aubert, Xavier L.,, Aubert, Xavier L., Beersma, Domien G.M.,, Most, Els I. S., Gil, Enrique A., Møst, Els I.S.,   +12 more
core   +1 more source