Results 41 to 50 of about 16,131 (160)

Circadian Chimeric Mice Reveal an Interplay Between the Suprachiasmatic Nucleus and Local Brain Clocks in the Control of Sleep and Memory

open access: yesFrontiers in Neuroscience, 2021
Sleep is regulated by circadian and homeostatic processes. Whereas the suprachiasmatic nucleus (SCN) is viewed as the principal mediator of circadian control, the contributions of sub-ordinate local circadian clocks distributed across the brain are ...
Elizabeth Susan Maywood   +4 more
doaj   +1 more source

SUDAZFLNC – a curated and searchable online database for zebrafish lncRNAs, mRNAs, miRNAs, and circadian expression profiles

open access: yesComputational and Structural Biotechnology Journal
The zebrafish (Danio rerio) has emerged as a model organism for investigating lncRNAs-driven fundamental biological processes, such as circadian rhythms, physiology, metabolism, and various diseases.
Shital Kumar Mishra, Han Wang
doaj   +1 more source

Endogenous melatonin promotes rhythmic recruitment of neutrophils toward an injury in zebrafish

open access: yesScientific Reports, 2017
Neutrophil recruitment to injured tissue appears to be an evolutionarily conserved strategy for organisms to fight against exogenous insults. Recent studies have shown rhythmic migration of neutrophils and several factors, including melatonin, have been ...
Da-long Ren   +4 more
doaj   +1 more source

Intestinal Stem Cells Exhibit Conditional Circadian Clock Function

open access: yesStem Cell Reports, 2018
Summary: The circadian clock is a molecular pacemaker that produces 24-hr physiological cycles known as circadian rhythms. How the clock regulates stem cells is an emerging area of research with many outstanding questions.
Kathyani Parasram   +6 more
doaj   +1 more source

A miR-219-5p-bmal1b negative feedback loop contributes to circadian regulation in zebrafish

open access: yesCommunications Biology
MicroRNAs post-transcriptionally regulate gene expression and contribute to numerous life processes, including circadian rhythms. However, whether miRNAs contribute to zebrafish circadian regulation has not yet been investigated.
Lianxin Wu   +3 more
doaj   +1 more source

Circadian and Circalunar Clock Interactions in a Marine Annelid

open access: yesCell Reports, 2013
Life is controlled by multiple rhythms. Although the interaction of the daily (circadian) clock with environmental stimuli, such as light, is well documented, its relationship to endogenous clocks with other periods is little understood.
Juliane Zantke   +8 more
doaj   +1 more source

Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice

open access: yesMedicina, 2022
Background and Objectives: The antidiabetic agent metformin is known to activate AMP-activated protein kinase (AMPK) in various tissues. Because AMPK can modulate intracellular circadian clocks through regulating the stability of clock components, a ...
Nazmul Hasan   +7 more
doaj   +1 more source

Food as circadian time cue for appetitive behavior [version 1; peer review: 5 approved]

open access: yesF1000Research, 2020
Feeding schedules entrain circadian clocks in multiple brain regions and most peripheral organs and tissues, thereby synchronizing daily rhythms of foraging behavior and physiology with times of day when food is most likely to be found.
Ralph E. Mistlberger
doaj   +1 more source

An adipokine feedback regulating diurnal food intake rhythms in mice

open access: yeseLife, 2020
Endogenous circadian clocks have evolved to anticipate 24 hr rhythms in environmental demands. Recent studies suggest that circadian rhythm disruption is a major risk factor for the development of metabolic disorders in humans. Conversely, alterations in
Anthony H Tsang   +4 more
doaj   +1 more source

Cut the noise or couple up: Coordinating circadian and synthetic clocks

open access: yesiScience, 2021
Summary: Circadian clocks are important to much of life on Earth and are of inherent interest to humanity, implicated in fields ranging from agriculture and ecology to developmental biology and medicine.
Chris N. Micklem, James C.W. Locke
doaj   +1 more source

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