Results 21 to 30 of about 15,542 (119)
The circadian clock and asthma [PDF]
Thorax, 2013 It is characteristic of asthma that symptoms worsen overnight, particularly in the early hours of the morning. Nocturnal symptoms in asthma are common and are an important indicator for escalation of treatment. An extensive body of research has demonstrated that nocturnal symptoms of cough and dyspnea are accompanied by circadian variations in airway ...
Durrington, Hannah J.; id_orcid 0000-0002-9990-9446 +3 more
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Cancer and the Circadian Clock
Cancer Research, 2019 Abstract The circadian clock is a master regulator of mammalian physiology, regulating daily oscillations of crucial biological processes and behaviors. Notably, circadian disruption has recently been identified as an independent risk factor for cancer and classified as a carcinogen.
Ayesha A, Shafi, Karen E, Knudsen
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The Circadian Clock and Viral Infections [PDF]
Journal of Biological Rhythms, 2020 The circadian clock controls several aspects of mammalian physiology and orchestrates the daily oscillations of biological processes and behavior. Our circadian rhythms are driven by an endogenous central clock in the brain that synchronizes with clocks in peripheral tissues, thereby regulating our immune system and the severity of infections.
Helene Borrmann +2 more
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Feeding and circadian clocks [PDF]
Reproduction Nutrition Development, 2006 The mammalian genome encodes at least a dozen of genes directly involved in the regulation of the feedback loops constituting the circadian clock. The circadian system is built up on a multitude of oscillators organized according to a hierarchical model in which neurons of the suprachiasmatic nuclei of the hypothalamus may drive the central circadian ...
Lissia, Pardini, Bertrand, Kaeffer
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Circadian Clocks: Translation Lost [PDF]
Current Biology, 2005 One of the big questions in biological rhythms research is how a stable and precise circa-24 hour oscillation is generated on the molecular level. While increasing complexity seemed to be the key, a recent report suggests that circa-24 hour rhythms can be generated by just four molecules incubated in a test tube.
Roenneberg, T, Merrow, M
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Circadian clocks: running on redox.
Cell, 2001 The circadian clock in all organisms is so intimately linked to light reception that it appears as if evolution has simply wired a timer into the mechanism that processes photic information. Several recent studies have provided new insights into the role of light input pathways in the circadian system of Arabidopsis.
Merrow, Martha, Roenneberg, Till
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The circadian clock and behavior
Behavioural Brain Research, 2001 Temporal organization is a fundamental feature of all living systems. Timing is essential for development, growth and differentiation and in the mature organism, it is essential to maintain normal physiology and behavior. The biological entity that permits an organism's day/night organization is the circadian system.
Albrecht, U., Oster, H.
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Circadian Clocks and Metabolism [PDF]
, 2013 Circadian clocks maintain periodicity in internal cycles of behavior, physiology, and metabolism, enabling organisms to anticipate the 24-h rotation of the Earth. In mammals, circadian integration of metabolic systems optimizes energy harvesting and utilization across the light/dark cycle.
Biliana, Marcheva +5 more
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Entrainment of the Human Circadian Clock [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2007 Humans are an excellent model system for studying entrainment of the circadian clock in the real world. Unlike the situation in laboratory experiments, entrainment under natural conditions is achieved by different external signals as well as by internal signals generated by multiple feedbacks within the system (e.g., behavior-dependent light and ...
Roenneberg, T., Merrow, M.
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Circadian Clocks, Stress, and Immunity [PDF]
Frontiers in Endocrinology, 2016 In mammals, molecular circadian clocks are present in most cells of the body, and this circadian network plays an important role in synchronizing physiological processes and behaviors to the appropriate time of day. The hypothalamic-pituitary-adrenal endocrine axis regulates the response to acute and chronic stress, acting through its final effectors -
Dumbell, R, Matveeva, O, Oster, H
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