Results 21 to 30 of about 5,427 (264)
The TIME FOR COFFEE gene maintains the amplitude and timing of Arabidopsis circadian clocks [PDF]
Plants synchronize developmental and metabolic processes with the earth's 24-h rotation through the integration of circadian rhythms and responses to light.
Amasino, R. +40 more
core +1 more source
The contributions of interlocking loops and extensive nonlinearity to the properties of circadian clock models [PDF]
Sensitivity and robustness are essential properties of circadian clock systems, enabling them to respond to the environment but resist noisy variations. These properties should be recapitulated in computational models of the circadian clock.
Andrew J Millar +15 more
core +1 more source
Spectres of Clock Evolution: Past, Present, and Yet to Come
Circadian clocks are phylogenetically widespread biological oscillators that allow organisms to entrain to environmental cycles and use their steady-state phase relationship to anticipate predictable daily phenomena – such as the light-dark transitions ...
Maria Luísa Jabbur +1 more
doaj +1 more source
Circadian clocks in the ovary [PDF]
Clock gene expression has been observed in tissues of the hypothalamic-pituitary-gonadal (HPG) axis. Whereas the contribution of hypothalamic oscillators to the timing of reproductive biology is well known, the role of peripheral oscillators like those in the ovary is less clear.
Michael T, Sellix, Michael, Menaker
openaire +2 more sources
ELF4 is required for oscillatory properties of the circadian clock [PDF]
Circadian clocks are required to coordinate metabolism and physiology with daily changes in the environment. Such clocks have several distinctive features, including a free-running rhythm of approximately 24 h and the ability to entrain to both light or ...
Nagy, Ferenc +22 more
core +1 more source
Cancer and the Circadian Clock
Abstract The circadian clock is a master regulator of mammalian physiology, regulating daily oscillations of crucial biological processes and behaviors. Notably, circadian disruption has recently been identified as an independent risk factor for cancer and classified as a carcinogen.
Ayesha A, Shafi, Karen E, Knudsen
openaire +3 more sources
The circadian clock of cyanobacteria [PDF]
A circadian clock, with physiological characteristics similar to those of eukaryotes, functions in the photosynthetic prokaryote, cyanobacteria. The molecular mechanism of this clock has been efficiently dissected using a luciferase reporter gene that reports the status of the clock.
T, Kondo, M, Ishiura
openaire +2 more sources
Disrupted circadian clocks and altered tissue mechanics in primary human breast tumours
Background Circadian rhythms maintain tissue homeostasis during the 24-h day-night cycle. Cell-autonomous circadian clocks play fundamental roles in cell division, DNA damage responses and metabolism.
Eleanor Broadberry +10 more
doaj +1 more source
Voluntary exercise can strengthen the circadian system in aged mice [PDF]
Consistent daily rhythms are important to healthy aging according to studies linking disrupted circadian rhythms with negative health impacts. We studied the effects of age and exercise on baseline circadian rhythms and on the circadian system's ability ...
I. Song +21 more
core +1 more source
The Circadian Clock in the Kidney [PDF]
Circadian variations in renal function were first described in the 19th century, and GFR, renal blood flow, urine production, and electrolyte excretion exhibit daily oscillations. These clinical observations are well established, but the underlying mechanisms that govern circadian fluctuations in kidney are not fully understood. Here we provide a brief
Lisa R, Stow, Michelle L, Gumz
openaire +2 more sources

