Results 131 to 140 of about 342,113 (368)

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

open access: yesAdvanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li   +12 more
wiley   +1 more source

Interactive features of proteins composing eukaryotic circadian clocks.

open access: yesAnnual Review of Biochemistry, 2014
Research into the molecular mechanisms of eukaryotic circadian clocks has proceeded at an electrifying pace. In this review, we discuss advances in our understanding of the structures of central molecular players in the timing oscillators of fungi ...
B. Crane, M. W. Young
semanticscholar   +1 more source

Circadian rhythms of proliferation events in two mouse carcinomas [PDF]

open access: yes, 2015
We studied the index of DNA synthesis (DNAs) of two cellular carcinomas: the hepatocellular ES12a and the mammary TN60 of mice, throughout one circadian cycle.
Andrini, Laura Beatríz   +6 more
core   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

open access: yesAdvanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong   +6 more
wiley   +1 more source

An Automated Organotypic SCN Culture System Revealing Novel Insights into VIP Regulation of Circadian Rhythm

open access: yesAdvanced Science, EarlyView.
An Automated ex vivo culture system BaSIC, tailored for SCN slices and cell culture, which automates medium exchange and ensures a stable internal environment is developed. BaSIC enables real‐time observation of tissue/cell responses to diverse but programmed stimuli.
Kui Han   +7 more
wiley   +1 more source

Circadian rhythms regulate the environmental responses of net CO2 exchange in bean and cotton canopies [PDF]

open access: yes, 2017
Studies on the dependence of the rates of ecosystem gas exchange on environmental parameters often rely on the up-scaling of leaf-level response curves ('bottom-up' approach), and/or the down-scaling of ecosystem fluxes ('top-down' approach), where one ...
Alday, Josu G.   +19 more
core   +4 more sources

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

open access: yesAdvanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu   +23 more
wiley   +1 more source

Does the circadian system regulate lactation?

open access: yesAnimal, 2012
Environmental variables such as photoperiod, heat, stress, nutrition and other external factors have profound effects on quality and quantity of a dairy cow's milk.
K. Plaut, T. Casey
doaj   +1 more source

Running on time: the role of circadian clocks in the musculoskeletal system

open access: yesBiochemical Journal, 2014
The night and day cycle governs the circadian (24 hourly) rhythm of activity and rest in animals and humans. This is reflected in daily changes of the global gene expression pattern and metabolism, but also in the local physiology of various tissues.
M. Dudek, Q. Meng
semanticscholar   +1 more source

Plant Robotics for Sustainable and Environmentally Friendly Robots: Insights from Actuation Characteristics

open access: yesAdvanced Science, EarlyView.
Plants are promising materials for building sustainable and eco‐friendly robots due to their inherent multifunctionality, with actuation playing a crucial role. This article focuses on the physical movements of plants and, from the perspective of actuation characteristics, explores representative plant species and their behaviors, the current state of ...
Kazuya Murakami   +8 more
wiley   +1 more source

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