Results 171 to 180 of about 336,986 (421)

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

Animal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li, Yanyan Sun, Jingwei Yuan, Xiangchen Li, Lei Shi, Adamu Mani Isa, Yuanmei Wang, Pingzhuang Ge, Yunhe Zong, Panlin Wang, Jilan Chen   +10 more
wiley   +1 more source

FLOWERING LOCUS C -dependent and -independent regulation of the circadian clock by the autonomous and vernalization pathways [PDF]

, 2006
Background The circadian system drives pervasive biological rhythms in plants. Circadian clocks integrate endogenous timing information with environmental signals, in order to match rhythmic outputs to the local day/night cycle.
Amasino, Richard M., Davis, Seth J., Lynn, James R., Michaels, Scott D., Millar, A. J. (Andrew J.), Salathia, Neeraj   +5 more
core   +4 more sources

Local renal circadian clocks control fluid-electrolyte homeostasis and BP.

Journal of the American Society of Nephrology, 2014
The circadian timing system is critically involved in the maintenance of fluid and electrolyte balance and BP control. However, the role of peripheral circadian clocks in these homeostatic mechanisms remains unknown. We addressed this question in a mouse
Natsuko Tokonami, D. Mordasini, S. Pradervand, G. Centeno, Céline Jouffe, M. Maillard, O. Bonny, F. Gachon, R. A. Gomez, M. Sequeira-Lopez, D. Firsov   +10 more
semanticscholar   +1 more source

Feasibility and population exposure of 5‐fluorouracil using therapeutic drug monitoring (PREDICT‐5FU): A multicentre clinical trial

British Journal of Clinical Pharmacology, EarlyView.
Aim PREDICT‐5FU aimed to document 5‐fluorouracil (5FU) exposure in a cancer population and to evaluate the feasibility of 5FU and capecitabine therapeutic drug monitoring (TDM) in patients receiving standard doses and schedules. Methods Multicentre, prospective, observational single‐arm study.
Sarah Glewis, Michael Michael, Howard Gurney, Ian Olver, Nicholas Zdenkowski, Stephen Ackland, Craig Kukard, Madawa Jayawardana, S. Sandun M. Silva, Marliese Alexander, Jeanne Tie, Peter Galettis, Jennifer H. Martin   +12 more
wiley   +1 more source

Spontaneous circadian rhythms in a cold-Adapted natural isolate of Aureobasidium pullulans [PDF]

, 2017
Indexación: Scopus.Circadian systems enable organisms to synchronize their physiology to daily and seasonal environmental changes relying on endogenous pacemakers that oscillate with a period close to 24 h even in the absence of external timing cues. The
Bellora, N., Canessa, P., Franco, D.L., Larrondo, L.F., Libkind, D., Marpegan, L., Olivares-Yañez, C., Pérez-Lara, R., Risau-Gusman, S.   +8 more
core   +3 more sources

Metabolic and nontranscriptional circadian clocks: eukaryotes.

Annual Review of Biochemistry, 2014
Circadian clocks are cellular timekeeping mechanisms that coordinate behavior and physiology around the 24-h day in most living organisms. Misalignment of an organism's clock with its environment is associated with long-term adverse fitness consequences,
A. B. Reddy, Guillaume Rey
semanticscholar   +1 more source

Medications, epilepsy and climate change: Added layers of complexity

British Journal of Clinical Pharmacology, EarlyView.
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi, Seyhmus Gavas, Sanjay M. Sisodiya   +2 more
wiley   +1 more source

Thousands of oscillating LncRNAs in the mouse testis

Computational and Structural Biotechnology Journal
The long noncoding RNAs (lncRNAs) are involved in numerous fundamental biological processes, including circadian regulation. Although recent studies have revealed insights into the functions of lncRNAs, how the lncRNAs regulate circadian rhythms still ...
Shital Kumar Mishra, Taole Liu, Han Wang
doaj  

Intestinal Stem Cells Exhibit Conditional Circadian Clock Function

Stem Cell Reports, 2018
Summary: The circadian clock is a molecular pacemaker that produces 24-hr physiological cycles known as circadian rhythms. How the clock regulates stem cells is an emerging area of research with many outstanding questions.
Kathyani Parasram, Nathaniel Bernardon, Maha Hammoud, Hanna Chang, Li He, Norbert Perrimon, Phillip Karpowicz   +6 more
doaj  

Mathematical models of the Arabidopsis circadian oscillator [PDF]

Biophysica 4 (2024) 267-282
We review the construction and evolution of mathematical models of the Arabidopsis circadian clock, structuring the discussion into two distinct historical phases of modeling strategies: extension and reduction. The extension phase explores the bottom-up assembly of regulatory networks introducing as many components and interactions as possible in ...
arxiv   +1 more source