Results 171 to 180 of about 342,113 (368)
Chronic Inflammation Disrupts Circadian Rhythms in Splenic CD4+ and CD8+ T Cells in Mice
CellsInternal circadian clocks coordinate 24 h rhythms in behavior and physiology. Many immune functions show daily oscillations, and cellular circadian clocks can impact immune functions and disease outcome.
Misa Hirose +7 more
doaj +1 more source
Annals of Neurology, EarlyView.Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji +10 more
wiley +1 more source
Back Again to the Future: A New Era for Cerebroprotection
Annals of Neurology, EarlyView.Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley +1 more source
Exercise strengthens circadian clocks
The Journal of Physiology, 2012 We all know that exercise can increase the strength of our muscles. In this issue of The Journal of Physiology, new research by Schroeder and colleagues (2012) demonstrates that exercise can also have a big impact on the circadian system, a network of structures that regulate daily rhythms in physiology.
openaire +4 more sources
Annals of Neurology, EarlyView.Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito +10 more
wiley +1 more source
The influence of circadian rhythms on carbohydrate metabolism in health and in diabetes mellitus
Сахарный диабетMost processes in the human body and other living organisms are governed by biorhythms. The term biorhythms refers to periodically recurring changes in biological processes.
I. V. Misnikova, D. E. Zoloeva
doaj +1 more source
Circadian clocks optimally adapt to sunlight for reliable synchronization
, 2013 Yoshihiko Hasegawa, Masanori Arita
openalex +1 more source
Phytoplankton Tune Local pH to Actively Modulate Circadian Gravitactic Behavior
Advanced Physics Research, EarlyView.Diel vertical migration hides an unexpected twist: Phytoplankton quietly engineer their local pH landscape, splitting into behaviorally distinct sub‐groups which stay separated even in identical conditions. Circadian pH changes, occuring over the course of a day, reshape their gravitactic behavior and physiological functions in ways scientists have ...
Arkajyoti Ghoshal +4 more
wiley +1 more source