Results 101 to 110 of about 95,486 (334)

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

open access: yesAnimal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li   +10 more
wiley   +1 more source

Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan   +13 more
wiley   +1 more source

Keeping development on time: Insights into post‐transcriptional mechanisms driving oscillatory gene expression during vertebrate segmentation

open access: yesWIREs RNA, Volume 14, Issue 1, January/February 2023., 2023
Genetic oscillators play crucial roles in development. The hairy/Enhancer of split gene family (Hes/her) undergo cell‐autonomous genetic oscillations to regulate the timing of vertebrate segmentation and neural cell proliferation and differentiation. mRNA stability and translation are tightly regulated to maintain oscillatory expression.
Monica C. Blatnik   +2 more
wiley   +1 more source

A Joint Pharmacometric Model of Iohexol and Creatinine Administered through a Meat Meal to Assess GFR and Renal OCT2/MATE Activity

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurately assessing glomerular filtration rate (GFR) from plasma creatinine concentrations is challenging in patients with unstable renal function. This study aimed to refine the understanding of creatinine kinetics for more reliable assessments of GFR and net creatinine tubular secretion (nCTS) via OCT2/MATE in humans.
Zhendong Chen   +5 more
wiley   +1 more source

Development of salivary cortisol circadian rhythm in preterm infants.

open access: yesPLoS ONE, 2017
ObjectivesTo investigate at what age preterm infants develop a salivary cortisol circadian rhythm and identify whether it is dependent on gestational age and/or postnatal age.
Katrin Ivars   +5 more
doaj   +1 more source

Transition from 12 to near-24 hours glucose circadian rhythm on relaxation of a hyperglycemic condition [PDF]

open access: yesarXiv, 2008
A composite, exponential relaxation function, modulated by a periodic component, was used to fit to an experimental time series of blood glucose levels. The 11 parameters function that allows for the detection of a possible rhythm transition was fitted to the experimental time series using a genetic algorithm. It has been found that the relaxation from
arxiv  

Temporal profiling of M‐TEER‐related complications

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Transcatheter edge‐to‐edge repair of the mitral valve (M‐TEER) is known for its low complication rates. However, the optimal level and duration of post‐procedural care remain unclear. This study aimed to identify the specific timeframe of post‐procedural complications following M‐TEER.
Jafer Haschemi   +8 more
wiley   +1 more source

Current role and future perspectives of electroacupuncture in circadian rhythm regulation

open access: yesHeliyon, 2023
In recent years, in-depth research on chronobiology has been conducted, and the circadian rhythm has become a new target for the treatment of diseases. Circadian rhythms are closely related to the normal physiological functions of organisms.
Min Yuan   +5 more
doaj  

Circadian rhythms [PDF]

open access: yesFEBS Letters, 2011
Michael Brunner, Martha Merrow
openaire   +2 more sources

Global artificial light masks biologically important light cycles of animals

open access: yesFrontiers in Ecology and the Environment, EarlyView.
We document the importance of low‐light conditions in 136 animal species and then translate the new world atlas of skyglow, which reports artificial night sky brightness, into estimates of anthropogenic illuminance (that is, artificial light reaching Earth's surface).
Brett M Seymoure   +7 more
wiley   +1 more source

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