Results 31 to 40 of about 136,810 (312)

Metals and Circadian Rhythms [PDF]

, 2017
Circadian rhythms describe the behavioral and physiological changes that occur in living organisms in order to attune to a 24 hour cycle of day and night. The most striking aspect of circadian function is the sleep-wake cycle, however many other physiological processes are regulated in 24 hour oscillations, including blood pressure, body temperature ...
Nancy L, Parmalee, Michael, Aschner
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Reduced expression of the PER2 protein contributes to β₁-AA-induced cardiac autophagy rhythm disorders

Acta Biochimica et Biophysica Sinica
Heart failure may be linked to fluctuations in the rhythm of autophagy in cardiomyocytes throughout the day. Circadian rhythms depend on the regulation of core biological clock proteins, with PER2 playing a crucial role.
Li Pengjia, Feng Jiayan, Guo Jiao, Xue Jin, Li Yang, Wen Shiyuan, Wang Xiaohui, Liu Huirong, Wang Li   +8 more
doaj   +1 more source

Rheostatic Balance of Circadian Rhythm and Autophagy in Metabolism and Disease

Frontiers in Cell and Developmental Biology, 2020
Circadian rhythms are physical, behavioral and environmental cycles that respond primarily to light and dark, with a period of time of approximately 24 h.
Xiang Wang, Zhijie Xu, Yuan Cai, Shuangshuang Zeng, Bi Peng, Xinxin Ren, Yuanliang Yan, Zhicheng Gong, Zhicheng Gong   +8 more
doaj   +1 more source

ELF4 is required for oscillatory properties of the circadian clock [PDF]

, 2007
Circadian clocks are required to coordinate metabolism and physiology with daily changes in the environment. Such clocks have several distinctive features, including a free-running rhythm of approximately 24 h and the ability to entrain to both light or ...
Nagy, Ferenc, Davis, Seth J, Gyula, Péter, Amasino, R., Doyle, M. R., Davis, S., Millar, A., Hall, Anthony, Amasino, Richard M, Davis, S. J., McWatters, Harriet G, Doyle, M., Doyle, Mark R, Kolmos, E., Amasino, R. M., Millar, A. J., Gyula, P., McWatters, H. G., Millar, Andrew J; id_orcid, Hall, A., Nagy, F., McWatters, H., Kolmos, Elsebeth   +22 more
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Clockwork green – the circadian oscillator in Arabidopsis

, 2006
Schöning JC, Streitner C, Staiger D. Clockwork green – the circadian oscillator in Arabidopsis. Biological Rhythm Research. 2006;37(4):335-352.Although rhythmic leaf movement in a higher plant was the first physiological process recognised to be under ...
Schöning, Jan C., Staiger, Dorothee, Streitner, Corinna   +2 more
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Circadian Rhythms in Immunity [PDF]

Current Allergy and Asthma Reports, 2020
This review is focused on the existing evidence for circadian control of innate and adaptive immune responses to provide a framework for evaluating the contributions of diurnal rhythms to control of infections and pathogenesis of disease.Circadian rhythms driven by cell-autonomous biological clocks are central to innate and adaptive immune responses ...
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Deciphering Lipid Metabolic Landscape of Sorafenib-Treated Hepatocellular Carcinoma by Mass Spectrometry Imaging and Transcriptomics

Biomolecules
Although sorafenib (SOR) is effective for advanced hepatocellular carcinoma (HCC), significant metabolic heterogeneity limits its therapeutic effect. In this study, we employed high-resolution matrix-assisted laser desorption/ionization mass spectrometry
Dongsheng Li, Yuanyuan Tuo, Luheng Sai, Xiunan Xu, Fujuan Peng, Zhipeng Yan, Qin Yang, Huifang Zhao, Ruiping Zhang   +8 more
doaj   +1 more source

Circadian rhythms and cancers: the intrinsic links and therapeutic potentials

Journal of Hematology & Oncology, 2022
The circadian rhythm is an evolutionarily conserved time-keeping system that comprises a wide variety of processes including sleep–wake cycles, eating–fasting cycles, and activity–rest cycles, coordinating the behavior and physiology of all organs for ...
Li Zhou, Zhe Zhang, Edouard Nice, Canhua Huang, Wei Zhang, Yong Tang   +5 more
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Smartphone Sensor Data for Identifying and Monitoring Symptoms of Mood Disorders: A Longitudinal Observational Study

JMIR Mental Health, 2022
BackgroundMood disorders are burdensome illnesses that often go undetected and untreated. Sensor technologies within smartphones may provide an opportunity for identifying the early changes in circadian rhythm and social support ...
Taylor A Braund, May The Zin, Tjeerd W Boonstra, Quincy J J Wong, Mark E Larsen, Helen Christensen, Gabriel Tillman, Bridianne O’Dea   +7 more
doaj   +1 more source

Circadian Disruption Primes Myofibroblasts for Accelerated Activation as a Mechanism Underpinning Fibrotic Progression in Non-Alcoholic Fatty Liver Disease

, 2023
Circadian rhythm governs many aspects of liver physiology and its disruption exacerbates chronic disease. CLOCKΔ19 mice disrupted circadian rhythm and spontaneously developed obesity and metabolic syndrome, a phenotype that parallels the progression of ...
Varinder S. Athwal, Athwal, Varinder; id_orcid, Oliver Street, Hanley, Neil A., Street, Oliver; id_orcid, Neil A. Hanley, Purssell, Huw, Leo Zeef, Jokl, Elliot, Simpson, Kara, Meng, Qing Jun, Zeef, Leo, Ian Donaldson, Karen Piper Hanley, Hanley, Karen Piper; id_orcid, James Pritchett, Athwal, Varinder S., Elliot Jokl, Donaldson, Ian, Kara Simpson, Adegboye, Oluwatobi, Jessica Llewellyn, Hanley, Neil A, Jokl, Elliot; id_orcid, Street, Oliver, Llewellyn, Jessica, Pritchett, James, Oluwatobi Adegboye, Indra Neil Guha, Huw Purssell, Guha, Indra Neil, Lucy Bennett, Bennett, Lucy, Qing-Jun Meng, Meng, Qing-Jun, Piper Hanley, Karen, Donaldson, Ian; id_orcid, Meng, Qing-Jun; id_orcid, Athwal, Varinder S   +38 more
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