Results 31 to 40 of about 358,769 (307)

Circadian Rhythms in Cyanobacteria [PDF]

Microbiology and Molecular Biology Reviews, 2015
SUMMARY Life on earth is subject to daily and predictable fluctuations in light intensity, temperature, and humidity created by rotation of the earth. Circadian rhythms, generated by a circadian clock, control temporal programs of cellular physiology to facilitate adaptation to daily environmental changes.
Cohen, Susan E, Golden, Susan S
openaire   +4 more sources

Reduced expression of the PER2 protein contributes to β₁-AA-induced cardiac autophagy rhythm disorders

Acta Biochimica et Biophysica Sinica
Heart failure may be linked to fluctuations in the rhythm of autophagy in cardiomyocytes throughout the day. Circadian rhythms depend on the regulation of core biological clock proteins, with PER2 playing a crucial role.
Li Pengjia, Feng Jiayan, Guo Jiao, Xue Jin, Li Yang, Wen Shiyuan, Wang Xiaohui, Liu Huirong, Wang Li   +8 more
doaj   +1 more source

Rheostatic Balance of Circadian Rhythm and Autophagy in Metabolism and Disease

Frontiers in Cell and Developmental Biology, 2020
Circadian rhythms are physical, behavioral and environmental cycles that respond primarily to light and dark, with a period of time of approximately 24 h.
Xiang Wang, Zhijie Xu, Yuan Cai, Shuangshuang Zeng, Bi Peng, Xinxin Ren, Yuanliang Yan, Zhicheng Gong, Zhicheng Gong   +8 more
doaj   +1 more source

Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1;2/TNF [PDF]

, 2012
Introduction: Circadian rhythms play an important role in the body and in single cells. Rhythms of molecular clocks have not been investigated in synovial fibroblasts (SF) of patients with osteoarthritis (OA) and rheumatoid arthritis (RA).
Haas, Stefanie, Stefanie Haas, Rainer H Straub, Straub, Rainer H.   +3 more
core   +1 more source

Deciphering Lipid Metabolic Landscape of Sorafenib-Treated Hepatocellular Carcinoma by Mass Spectrometry Imaging and Transcriptomics

Biomolecules
Although sorafenib (SOR) is effective for advanced hepatocellular carcinoma (HCC), significant metabolic heterogeneity limits its therapeutic effect. In this study, we employed high-resolution matrix-assisted laser desorption/ionization mass spectrometry
Dongsheng Li, Yuanyuan Tuo, Luheng Sai, Xiunan Xu, Fujuan Peng, Zhipeng Yan, Qin Yang, Huifang Zhao, Ruiping Zhang   +8 more
doaj   +1 more source

Circadian rhythms and cancers: the intrinsic links and therapeutic potentials

Journal of Hematology & Oncology, 2022
The circadian rhythm is an evolutionarily conserved time-keeping system that comprises a wide variety of processes including sleep–wake cycles, eating–fasting cycles, and activity–rest cycles, coordinating the behavior and physiology of all organs for ...
Li Zhou, Zhe Zhang, Edouard Nice, Canhua Huang, Wei Zhang, Yong Tang   +5 more
doaj   +1 more source

Genetics of Circadian Rhythms

Neurologic Clinics, 2019
In mammals, genetic influences of circadian rhythms occur at many levels. A set of core "clock genes" have been identified that form a feedback loop of gene transcription and translation. The core genetic clockwork generates circadian rhythms in cells throughout the body.
Martha Hotz, Vitaterna, Kazuhiro, Shimomura, Peng, Jiang   +2 more
openaire   +3 more sources

Smartphone Sensor Data for Identifying and Monitoring Symptoms of Mood Disorders: A Longitudinal Observational Study

JMIR Mental Health, 2022
BackgroundMood disorders are burdensome illnesses that often go undetected and untreated. Sensor technologies within smartphones may provide an opportunity for identifying the early changes in circadian rhythm and social support ...
Taylor A Braund, May The Zin, Tjeerd W Boonstra, Quincy J J Wong, Mark E Larsen, Helen Christensen, Gabriel Tillman, Bridianne O’Dea   +7 more
doaj   +1 more source

Circadian rhythms in parasites

PLOS Pathogens, 2017
Copyright: © 2017 Rijo-Ferreira et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Filipa Rijo-Ferreira, Joseph S. Takahashi, Luisa M. Figueiredo   +2 more
openaire   +5 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source