Results 41 to 50 of about 136,810 (312)

Mucosal circadian rhythm pathway genes altered by aging and periodontitis

PLoS ONE, 2022
As circadian processes can impact the immune system and are affected by infections and inflammation, this study examined the expression of circadian rhythm genes in periodontitis.
Jeffrey L. Ebersole, Octavio A. Gonzalez
doaj   +2 more sources

The contributions of interlocking loops and extensive nonlinearity to the properties of circadian clock models [PDF]

, 2010
Sensitivity and robustness are essential properties of circadian clock systems, enabling them to respond to the environment but resist noisy variations. These properties should be recapitulated in computational models of the circadian clock.
Andrew J Millar, Painter, Kevin J., Saithong Treenut, Saithong T., Painter K. J., Painter Kevin J., Saithong, Treenut, Kevin J Painter, Millar Andrew J., Andrew J. Millar, Millar A. J., Millar, Andrew J; id_orcid, Treenut Saithong, Painter, Kevin J, Millar, Andrew J., Kevin J. Painter   +15 more
core   +1 more source

Circadian rhythms and diabetes [PDF]

Journal of Diabetes Investigation, 2011
All free‐living organisms are regulated by the 24‐h light and dark cycle produced by Earth’s rotation. In mammals, circadian rhythms are indispensble for the regulation of physiological and biochemical processes in the body. In 1972, the suprachiasmatic nucleus was shown to be required for daily rhythms in animal behavior1.
Kurose, Takeshi, Yabe, Daisuke, Inagaki, Nobuya   +2 more
openaire   +2 more sources

Chronobiology and Mood Disorders [PDF]

Psikiyatride Güncel Yaklaşımlar, 2011
Living organizms show cyclic rhythmicity in a variety of physiological, hormonal, behavioral, and psychological processes. Sleep-wake cycles, body temperature, hormone levels, mood and cognition display a circadian rhythm in humans.
Yavuz Selvi, Lutfullah Besiroglu, Adem Aydin   +2 more
doaj  

CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in expression of coherent circadian rhythm but not in generation of circadian oscillation in the neonatal mouse SCN

Scientific Reports, 2021
Clock genes Cry1 and Cry2, inhibitory components of core molecular feedback loop, are regarded as critical molecules for the circadian rhythm generation in mammals.
Daisuke Ono, Ken-ichi Honma, Christoph Schmal, Toru Takumi, Takeshi Kawamoto, Katsumi Fujimoto, Yukio Kato, Sato Honma   +7 more
doaj   +1 more source

Disruption in the regulation of casein kinase 2 in circadian rhythm leads to pathological states: cancer, diabetes and neurodegenerative disorders

Frontiers in Molecular Neuroscience, 2023
IntroductionCircadian rhythm maintains the sleep–wake cycle in biological systems. Various biological activities are regulated and modulated by the circadian rhythm, disruption of which can result in onset of diseases.
Md. Zubbair Malik, Mohammed Dashti, Yasmin Fatima, Arshad Channanath, Sumi Elsa John, R. K. Brojen Singh, Fahd Al-Mulla, Thangavel Alphonse Thanaraj   +7 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Closed-loop cascade nanozyme strategy for mutually reinforced catalytic and mild-temperature photothermal therapeutic effects

Journal of Nanobiotechnology
Nanocatalysis coupled with photothermal therapy is a potent anti-cancer approach, yet its clinical utility is limited by low concentration of tumor substrate, redox interference, and risks of overheating normal tissues.
Fan Yang, Chunyu Yan, Nannan Li, Xinxiu Jiang, Baojie Du, Peirong Bai, Liping Li, Ruiping Zhang   +7 more
doaj   +1 more source

Therapeutic potential of ginsenosides in circadian rhythm-based skin disorders

Journal of Ginseng Research
The circadian rhythm, a biological system all living organisms possess, has become increasingly important as sleep patterns become more irregular. Circadian rhythms affect various cell types (fibroblasts, fat cells, muscles, etc.) and organs (the liver ...
Heejun Ha, Heeseon Shin, Sukhyun Min, Natasha Christabella Sutopo, Khamit Yerkesh, Eunsun Jung, Minkyung Song, Jae Youl Cho, Jongsung Lee   +8 more
doaj   +1 more source

Circadian Rhythm Sleep Disorders [PDF]

Psikiyatride Güncel Yaklaşımlar, 2016
The circadian rhythm sleep disorders define the clinical conditions where sleep and ndash;wake rhythm is disrupted despite optimum environmental and social conditions.
Erhan Akinci, Fatma Ozlem Orhan
doaj   +1 more source