Results 51 to 60 of about 136,810 (312)

Modeling circadian and sleep-homeostatic effects on short-term interval timing [PDF]

, 2015
Short-term interval timing i.e., perception and action relating to durations in the seconds range, has been suggested to display time-of-day as well as wake dependent fluctuations due to circadian and sleep-homeostatic changes to the rate at which an ...
Jakub eSpäti, Meyer, Andrea Hans, Moriguchi, Yoshiya, Aritake, Sayaka, Hida, Akiko, Sayaka Aritake, Mishima, Kazuo, Yoshiya eMoriguchi, Späti, Jakub, Kitamura, Shingo, Yoshiya Moriguchi, Shigekazu eHiguchi, Jakub Späti, Kazuo Mishima, Shingo eKitamura, Akiko eHida, Kazuo eMishima, Andrea H. Meyer, Sayaka eAritake, Higuchi, Shigekazu, Shingo Kitamura, Shigekazu Higuchi, Andrea Hans Meyer, Akiko Hida   +23 more
core   +1 more source

Circadian rhythms and the kidney [PDF]

Nature Reviews Nephrology, 2018
Numerous physiological functions exhibit substantial circadian oscillations. In the kidneys, renal plasma flow, the glomerular filtration rate and tubular reabsorption and/or secretion processes have been shown to peak during the active phase and decline during the inactive phase.
Firsov D, Bonny O
openaire   +3 more sources

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

The impact of short-term changes in sleeping and eating patterns on glucometabolic health and gut microbiota in healthy young adults: a proof-of-concept controlled feeding study

Food Science and Human Wellness
Epidemiological studies showed that night workers are at higher risk of developing chronic metabolic diseases. However, no study has investigated the changes in circadian rhythms caused by a combined effect of sleep and diet in a real-life setting on ...
Jiehua Chen, Ruijie Zhang, Chao Zhou, Louise Weiwei Lu, Dana Feng, Haiqiao Zou, Ran Gao, Xinying Zhang, Peiyi Chen, Jiayue Zhu, Haoxie Xu, Nina Zeng, Cijuan Zhang, Bin Liu, Mingfu Wang, Qian Ge, Caiqun Ouyang, Feng Chen   +17 more
doaj   +1 more source

Genetics of Circadian Rhythms

Neurologic Clinics, 2019
In mammals, genetic influences of circadian rhythms occur at many levels. A set of core "clock genes" have been identified that form a feedback loop of gene transcription and translation. The core genetic clockwork generates circadian rhythms in cells throughout the body.
Martha Hotz, Vitaterna, Kazuhiro, Shimomura, Peng, Jiang   +2 more
openaire   +3 more sources

Circadian rhythms in RA [PDF]

Annals of the Rheumatic Diseases, 2003
Possible roles of cortisol and melatonin It is well known that some clinical signs and symptoms of rheumatoid arthritis (RA) vary within a day and between days, and the morning stiffness seen in patients with RA has become one of the diagnostic criteria of the disease (fig 1).1 Figure 1 Clinical signs and symptoms of articular inflammation in ...
CUTOLO, MAURIZIO, SERIOLO, BRUNO, Craviotto C, PIZZORNI, CARMEN, SULLI, ALBERTO   +4 more
openaire   +3 more sources

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

Galactose-modified small molecule modulator targets RORα to enhance circadian rhythm and alleviate periodontitis-associated alveolar bone loss

Bone Research
Circadian rhythm disorders are associated with dysfunction in inflammatory diseases, and targeted regulation of the circadian rhythm could serve as an intervention strategy. RORα/γ, as core components of circadian clock genes, positively modulate the key
Guangxia Feng, Zhiwen Liao, Yifan Wang, Qingming Tang, Nayun Li, Cheng Li, Yuqing Liu, Renlong Liu, Mingjian Cui, Wenjie Fan, Ying Yin, Lingkui Meng, Jing Zeng, Zetao Chen, Guanzheng Luo, Peng Xiang, Qian Wan, Lili Chen   +17 more
doaj   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Klebsiella pneumoniae alters zebrafish circadian rhythm via inflammatory pathways and is dependent on light cues

Heliyon
Klebsiella pneumoniae is an opportunistic pathogen causing severe infections. The circadian rhythm is the internal rhythm mechanism of an organism and plays an important role in coping with changes in the 24-h circadian rhythm.
Hui Ding, Xiao-chun Chen, Lin Wan, Ying-ying Zhang, Xiao-hong Rui, Tian He, Jun Liu, Zhong-bo Shang   +7 more
doaj   +1 more source