Results 71 to 80 of about 131,367 (307)
Advanced Intelligent Systems, EarlyView.Adaptive multi‐indicator contrastive predictive coding is introduced as a self‐supervised pretraining framework for multivariate EHR time series. An adaptive sliding‐window algorithm and 2D convolutional neural network encoder capture localized temporal patterns and global indicator dependencies, enabling label‐efficient disease prediction that ...
Hongxu Yuan +3 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji +10 more
wiley +1 more source
Phytoplankton Tune Local pH to Actively Modulate Circadian Gravitactic Behavior
Advanced Physics Research, EarlyView.Diel vertical migration hides an unexpected twist: Phytoplankton quietly engineer their local pH landscape, splitting into behaviorally distinct sub‐groups which stay separated even in identical conditions. Circadian pH changes, occuring over the course of a day, reshape their gravitactic behavior and physiological functions in ways scientists have ...
Arkajyoti Ghoshal +4 more
wiley +1 more source
Prevalence of OSA Risk and Bruxism in Children With Autism Spectrum Disorders
Autism Research, EarlyView.ABSTRACT Children with autism spectrum disorder (ASD) often present with sleep disorders, including obstructive sleep apnea (OSA), a condition characterized by upper airway obstruction during sleep. Bruxism has been recently described as being associated with OSA.
Anna Alessandri‐Bonetti +5 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia +3 more
wiley +1 more source
JMIR Medical InformaticsBackgroundWearable devices are increasingly used for monitoring health and detecting digital biomarkers related to chronic diseases such as metabolic syndrome (MetS).
Jeong-Kyun Kim, Sujeong Mun, Siwoo Lee
doaj +1 more source
Development of salivary cortisol circadian rhythm in preterm infants.
PLoS ONE, 2017 ObjectivesTo investigate at what age preterm infants develop a salivary cortisol circadian rhythm and identify whether it is dependent on gestational age and/or postnatal age.
Katrin Ivars +5 more
doaj +1 more source
The impact of urbanisation on social behaviour: a comprehensive review
Biological Reviews, EarlyView.ABSTRACT Urbanisation is a key driver of global environmental change and presents animals with novel stressors and challenges. It can fundamentally influence social behaviour and has the potential to reshape within‐ and between‐species social interactions. Given the role of social behaviour in reproductive fitness and survival, understanding how social
Avery L. Maune +2 more
wiley +1 more source
Biological Reviews, EarlyView.ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito +2 more
wiley +1 more source