Results 71 to 80 of about 95,486 (334)

Modulatory effects in circadian-related diseases via the reciprocity of tea polyphenols and intestinal microbiota

Food Science and Human Wellness, 2022
Tea is a widespread functional plant resource. Phytochemicals such as tea polyphenols (TP) can interact with the intestinal flora and participate in regulating the expression and rhythm of biological clock genes.
Ruonan Yan, Chi-Tang Ho, Xin Zhang
doaj  

Kernel Architecture of the Genetic Circuitry of the Arabidopsis Circadian System [PDF]

PLoS Comput. Biol. 12, e1004748 (2016), 2016
A wide range of organisms features molecular machines, circadian clocks, which generate endogenous oscillations with ~24 h periodicity and thereby synchronize biological processes to diurnal environmental fluctuations. Recently, it has become clear that plants harbor more complex gene regulatory circuits within the core circadian clocks than other ...
arxiv   +1 more source

Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics

Advanced Science, EarlyView.
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch, Brittany Scheid, Kathryn A Davis, Brian Litt, Arian Ashourvan   +4 more
wiley   +1 more source

Mediating effect of circadian rhythm between work stress and sleep quality in Chinese shift‐working nurses: A cross‐sectional survey

Nursing Open, Volume 10, Issue 2, Page 560-569, February 2023., 2023
Abstract Aim This study examined the mediating effect of circadian rhythm amplitude (LV) and stability (FR) between work stress and sleep quality among Chinese shift‐working nurses (SWNs). Design A cross‐sectional study. Methods Three‐hundred and seventy‐nine nurses working in shifts were investigated by convenient sampling from six hospitals in ...
Songqi Wu, Caiqin Wu, Xiaohan Wang, Wenling Fei, Yue Fu   +4 more
wiley   +1 more source

Circadian Rhythm Disruption Exacerbates Autoimmune Uveitis: The Essential Role of PER1 in Treg Cell Metabolic Support for Stability and Function

Advanced Science
Circadian rhythm plays a critical role in the progression of autoimmune diseases. While our previous study demonstrated the therapeutic effects of melatonin in experimental autoimmune uveitis, the involvement of circadian rhythm remained unclear. Using a
Wenjie Zhu, Guanyu Chen, Zhiqiang Xiao, Minzhen Wang, Zhuang Li, Yuxun Shi, Xiaohui Luo, Zuoyi Li, Haixiang Huang, Xiaoqing Chen, Lingyi Liang, Dan Liang   +11 more
doaj   +1 more source

Actionable Forecasting as a Determinant of Biological Adaptation

Advanced Science, EarlyView.
A new framework reveals how biological systems can achieve precise adaptation by tracking an actionable target that combines the current optimal state with its rate of change. This approach, implemented through dynamics‐informed neural networks, demonstrates that predictive mechanisms like circadian rhythms become beneficial when environmental sensing ...
Jose M. G. Vilar, Leonor Saiz
wiley   +1 more source

Simultaneous monitoring of activity and heart rate variability in depressed patients: A pilot study using a wearable monitor for 3 consecutive days

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 457-467, December 2022., 2022
By using a wearable sensor we examined 3‐dimensional acceleration and heart rate variability (HRV) simultaneously in depressive episode of mood disorders. We found reduced activity and altered HRV indices in depressed patients, compared with healthy participants, particularly in males. Moreover, we found that sympathetic load during sleep significantly
Norie Koga, Yoko Komatsu, Ryo Shinozaki, Ikki Ishida, Yusuke Shimizu, Sonoko Ishimaru, Hiroshi Kunugi   +6 more
wiley   +1 more source

Longitudinal Assessment of Seasonal Impacts and Depression Associations on Circadian Rhythm Using Multimodal Wearable Sensing [PDF]

arXiv, 2023
Objective: This study aimed to explore the associations between depression severity and wearable-measured circadian rhythms, accounting for seasonal impacts and quantifying seasonal changes in circadian rhythms.Materials and Methods: Data used in this study came from a large longitudinal mobile health study. Depression severity (measured biweekly using
arxiv  

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source

Linking chronic stress to insomnia symptoms in older adults: The role of stress co‐occurrence during the pandemic

Research in Nursing &Health, Volume 46, Issue 1, Page 68-79, February 2023., 2023
Abstract Studies examining the associations of chronic stressors with sleep health in older adults have shown conflicting results. While the COVID‐19 pandemic increased perceived stress at the population level, less is known about chronic stressors experienced by older adults in the context of the COVID‐19 pandemic and its impact on sleep health in an ...
Wan‐Chin Kuo, Anne L. Ersig, Fatih Kunkul, Roger L. Brown, Linda D. Oakley   +4 more
wiley   +1 more source