Results 71 to 80 of about 527,236 (300)

p38 Mitogen-activated Protein Kinase Regulates Oscillation of Chick Pineal Circadian Clock [PDF]

open access: yes, 2003
Extracellular signal-regulated kinase (ERK) and p38 are members of the mitogen-activated protein kinase (MAPK) family, and in some cases these kinases serve for closely related cellular functions within a cell. In a wide range of animal clock structures,
Fukada, Yoshitaka   +4 more
core   +1 more source

New Insights Into the Circadian Rhythm and Its Related Diseases

open access: yesFrontiers in Physiology, 2019
Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by the molecular circadian clock which acting on coordinating internal time with the external environment in a 24-h daily cycle.
Yanling Xie   +6 more
semanticscholar   +1 more source

Circadian rhythms in parasites

open access: yesPLOS Pathogens, 2017
Copyright: © 2017 Rijo-Ferreira et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Filipa Rijo-Ferreira   +2 more
openaire   +5 more sources

Chronobiology and Mood Disorders [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2011
Living organizms show cyclic rhythmicity in a variety of physiological, hormonal, behavioral, and psychological processes. Sleep-wake cycles, body temperature, hormone levels, mood and cognition display a circadian rhythm in humans.
Yavuz Selvi   +2 more
doaj  

Circadian Rhythm Sleep Disorders [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2016
The circadian rhythm sleep disorders define the clinical conditions where sleep and ndash;wake rhythm is disrupted despite optimum environmental and social conditions.
Erhan Akinci, Fatma Ozlem Orhan
doaj   +1 more source

Disruption in the regulation of casein kinase 2 in circadian rhythm leads to pathological states: cancer, diabetes and neurodegenerative disorders

open access: yesFrontiers in Molecular Neuroscience, 2023
IntroductionCircadian rhythm maintains the sleep–wake cycle in biological systems. Various biological activities are regulated and modulated by the circadian rhythm, disruption of which can result in onset of diseases.
Md. Zubbair Malik   +7 more
doaj   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

open access: yes, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Circadian rhythms and diabetes [PDF]

open access: yesJournal of Diabetes Investigation, 2011
All free‐living organisms are regulated by the 24‐h light and dark cycle produced by Earth’s rotation. In mammals, circadian rhythms are indispensble for the regulation of physiological and biochemical processes in the body. In 1972, the suprachiasmatic nucleus was shown to be required for daily rhythms in animal behavior1.
Kurose, Takeshi   +2 more
openaire   +2 more sources

Production and characterization of CSSI003 (2961) human induced pluripotent stem cells (iPSCs) carrying a novel puntiform mutation in RAI1 gene, Causative of Smith–Magenis syndrome [PDF]

open access: yes, 2018
Smith-Magenis syndrome (SMS) is a complex genetic disorder characterized by developmental delay, behavioural problems and circadian rhythm dysregulation. About 90% of SMS cases are due to a 17p11.2 deletion containing retinoic acid induced1 (RAI1) gene,
Altieri, Filomena   +12 more
core   +3 more sources

Circadian rhythm in bipolar disorder: A review of the literature

open access: yesPsychiatry and Clinical Neurosciences, 2018
Sleep disturbances and circadian rhythm dysfunction have been widely demonstrated in patients with bipolar disorder (BD). Irregularity of the sleep–wake rhythm, eveningness chronotype, abnormality of melatonin secretion, vulnerability of clock genes, and
Y. Takaesu
semanticscholar   +1 more source

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