Results 171 to 180 of about 206,395 (302)

Decoding Sleep Architecture from Ambulatory Basal Ganglia Signals in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Sleep architecture and circadian rhythms are frequently disrupted in Parkinson's disease (PD). BrainSense‐enabled neurostimulators combined with wearable technology enable chronic assessment of nocturnal brain activity, with potential for future diagnostics and personalized treatments. Objectives To neurophysiologically characterize
Alberto Averna   +15 more
wiley   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

Senotherapeutics for Knee Osteoarthritis

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman   +6 more
wiley   +1 more source

Buildings as accidental habitat: Where animals nest, sleep and forage

open access: yesPeople and Nature, EarlyView.
Abstract Animals have long inhabited human buildings alongside us, but our understanding comes from isolated studies, such as reports of a possum in the roof or a bat in our walls. What we lack is the building's perspective: which building features actually serve as habitat and for whom?
Bethany M. Kiss   +6 more
wiley   +1 more source

Fetoplacental Circadian Rhythms Develop and Then Synchronize to the Mother In Utero. [PDF]

open access: yesJ Biol Rhythms
Nikhil KL   +12 more
europepmc   +1 more source

Atopic dermatitis and attention‐deficit/hyperactivity disorder comorbidity in children and adolescents: Epidemiology, mechanisms, and clinical management

open access: yesPediatric Investigation, EarlyView.
This review synthesizes epidemiological evidence linking atopic dermatitis to attention‐deficit/hyperactivity disorder in children, proposes an “inflammation‐itch‐neurobehavioral axis” integrating sleep disruption, neuroendocrine dysregulation, and emerging neuro‐immune circuits, and outlines multidisciplinary management strategies targeting both skin ...
Qingyang Zhao   +11 more
wiley   +1 more source

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