Results 11 to 20 of about 247 (93)
Research progress in the treatment of bladder cancer based on nanotechnology [PDF]
, 2023 Bladder cancer is the most common malignant tumor in the urinary system. Currently, the clinical treatment options for bladder cancer mainly include surgery, chemotherapy, radiotherapy, immunotherapy, targeted therapy, photodynamic therapy, combination ...
CAO Xiangqian +5 more
core +1 more source
Competing endogenous RNA (ceRNA) networks and splicing switches in cervical cancer : HPV oncogenesis, clinical significance and therapeutic opportunities [PDF]
, 2022 Cervical cancer (CC) is the primary cause of female cancer fatalities in low-middle-income countries (LMICs). Persistent infections from the human papillomavirus (HPV) can result in cervical cancer.
Basera, Afra +6 more
core +1 more source
Extracellular vesicles in urological malignancies [PDF]
, 2021 Extracellular vesicles (EVs) are small lipid bound structures released from cells containing bioactive cargoes. Both the type of cargo and amount loaded varies compared to that of the parent cell.
Gregory, Christopher D. +2 more
core +2 more sources
A pH-responsive bi-MIL-88B MOF coated with folic acid-conjugated chitosan as a promising nanocarrier for targeted drug delivery of 5-Fluorouracil [PDF]
, 2023 Cancer has remained one of the leading causes of death worldwide, with a lack of effective treatment. The intrinsic shortcomings of conventional therapeutics regarding tumor specificity and non-specific toxicity prompt us to look for alternative ...
Abdullah F. AlAsmari +7 more
core +1 more source
Insights into the Evolving Roles of Circular RNAs in Cancer [PDF]
, 2021 The majority of RNAs transcribed from the human genome have no coding capacity and are termed non-coding RNAs (ncRNAs). It is now widely accepted that ncRNAs play key roles in cell regulation and disease.
Harper, KL, Mottram, TJ, Whitehouse, A
core +1 more source
The RNA interactome in the Hallmarks of Cancer
WIREs RNA, Volume 14, Issue 5, September/October 2023., 2023 Interactions of RNA molecules play key roles across all Hallmarks of Cancer and were not captured by large genome sequencing efforts. These RNA interactomics provide novel insight into cancer initiation and progression, and provide novel therapeutic targets for treatment of cancers and many other diseases.
Marta M. Gabryelska, Simon J. Conn
wiley +1 more source
WIREs RNA, Volume 14, Issue 3, May/June 2023., 2023 RNA splicing alteration is functionally linked to bladder cancer progression. Many players regulating the RNA splicing process (spliceosome components and splicing factors) and surrogate markers resulting from its alteration (mRNA splicing variants and ncRNAs) are drastically dysregulated in bladder cancer and play a pathophysiological role in this ...
Antonio J. Montero‐Hidalgo +6 more
wiley +1 more source
Ferroptosis-associated circular RNAs: Opportunities and challenges in the diagnosis and treatment of cancer [PDF]
, 2023 Ferroptosis is an emerging form of non-apoptotic regulated cell death which is different from cell death mechanisms such as autophagy, apoptosis and necrosis. It is characterized by iron-dependent lipid peroxide accumulation.
Junhu Wan +13 more
core +1 more source
Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring
Clinical and Translational Discovery, Volume 3, Issue 2, April 2023., 2023 A systematic overview of technical considerations in developping urine biomarkers. Seven classes of urine biomarkers are summarised for bladder cancer detection and monitoring. Highlight of limitations and future improvements. Abstract Urine‐based liquid biopsy has emerged as a non‐invasive and effective tool for early screening and diagnosis of ...
Yuchen Zeng +11 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, Volume 36, Issue 11, November 2022., 2022 Circular RNAs (circRNAs) have been implicated tumor initiation and progression. This study explored the role of circ_0081069 in regulating the malignancy of colorectal cancer (CRC). Hsa_circ_0081069 is upregulated in CRC tissues and cell lines, and silencing has_circ_0081069 impairs the malignancy of CRC cells.
Jingjing Xie +4 more
wiley +1 more source