Results 281 to 289 of about 45,661 (289)

circRNA and gastrointestinal cancer

Journal of Cellular Biochemistry, 2019
AbstractCircular RNAs (circRNAs) are a novel class of endogenous noncoding RNAs that form covalently closed continuous loops without 3′ end poly (A) tails and 5′ end caps. circRNAs are more conservative and stable than linear RNA. circRNAs can specifically bind to microRNAs as competing endogenous RNA, thereby directly or indirectly regulating the ...
Bing Luo, Chao‐ming Tang, Jing‐Song Chen   +2 more
openaire   +3 more sources

The Use of circRNAs as Biomarkers of Cancer

2021
CircRNAs are a subclass of lncRNAs that have been found to be abundantly present in a wide range of species, including humans. CircRNAs are generally produced by a noncanonical splicing event called backsplicing that is dependent on the canonical splicing machinery, giving rise to circRNAs classified into three main categories: exonic circRNA, circular
Gartze Mentxaka, Carla Solé, Charles H. Lawrie, Charles H. Lawrie   +3 more
openaire   +3 more sources

Benchmarking of computational methods for predicting circRNA-disease associations

Briefings Bioinform., 2023
Wei Lan, Yi Dong, Hongyu Zhang, Chunling Li, Qingfeng Chen, Jin Liu, Jianxin Wang, Yi-Ping Phoebe Chen   +7 more
semanticscholar   +1 more source

The complexity of the translation ability of circRNAs

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2016
Circular RNAs (circRNAs) are a new class of long non-coding RNAs that play a potential role in gene expression regulation, acting as efficient microRNAs sponges. The latest surprise concerning circRNAs is that we now know that they can serve as transcriptional activators in human cells, indicating that circRNAs are involved in important regulatory ...
Javier T. Granados-Riveron, Guillermo Aquino-Jarquin   +1 more
openaire   +3 more sources

CircRNA in cancer: Fundamental mechanism and clinical potential.

Cancer Letters, 2021
Liang Chen, G. Shan
semanticscholar   +1 more source

circRNA biogenesis competes with pre-mRNA splicing.

Molecules and Cells, 2014
Reut Ashwal-Fluss, M. Meyer, N. Pamudurti, Andranik Ivanov, Osnat Bartok, M. Hanan, Naveh Evantal, Sebastian Memczak, N. Rajewsky, S. Kadener   +9 more
semanticscholar   +1 more source

Deep learning models for disease-associated circRNA prediction: a review

Briefings Bioinform., 2022
Yaojia Chen, Jiacheng Wang, Chuyu Wang, Mingxin Liu, Q. Zou   +4 more
semanticscholar   +1 more source

CircRNA–miRNA interactions in atherogenesis

Molecular and Cellular Biochemistry, 2022
Kind-Leng Tong, Ke-En Tan, Yat-Yuen Lim, Xin-Yi Tien, P. Wong   +4 more
semanticscholar   +1 more source

circRNA-miRNA-mRNA in breast cancer.

Clinica chimica acta; international journal of clinical chemistry, 2021
Meilan Zhang, Xuechai Bai, Xuemei Zeng, Jiangrong Liu, Feng Liu, Zhiwei Zhang   +5 more
semanticscholar   +1 more source