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Role of lncRNAs and circRNAs in epilepsy
Ageing Research Reviews, 2022Epilepsy is a chronic disorder of with a high prevalence and extensive health burden in almost all age groups of the population. This condition is resulted from disturbance in the balance between excitatory and inhibitory factors in the brain. Genetic elements that affect synaptic connectivity, receptors functions or ion channels have been shown to ...
Soudeh Ghafouri-Fard +5 more
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The new function of circRNA: translation
Clinical and Translational Oncology, 2020Circular RNAs (circRNAs) have been considered a special class of non-coding RNAs without 5' caps and 3' tails which are covalently closed RNA molecules generated by back splicing of mRNA. For a long time, circRNAs have been considered to be directly involved in various biological processes as functional RNA.
Y. Shi, X. Jia, J. Xu
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Circular RNAs (circRNAs) in cancer
Cancer Letters, 2018Circular RNAs (circRNAs) are a class of non-coding RNAs that do not have 5' end caps or 3' end poly (A) tails. There are more than one hundred thousand genes that encode circRNAs. Clinical data show that there are differences in the expression of circRNAs in a variety of diseases, including cancer, suggesting that circRNA has a regulatory effect on ...
Ruoyu Zhou +11 more
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CircRNA Synthesis and Applications
Circular RNA (circRNA) is becoming an increasingly popular field of study and topic of interest. With that, there is a renewed and heightened interest in generating circular RNA for both research and clinical use. CircRNA generation began in the 1990s using in vitro chemical ligation and has since expanded out to include in vitro enzymatic synthesis ...Adam, Greasley +3 more
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CircRNAs in cancer therapy tolerance
Clinica Chimica ActaThe rapidly expanding field of circular RNA (circ-RNA) research has opened new avenues in cancer diagnostics and treatment, highlighting the role of serum circRNAs as potential biomarkers for assessing tumor therapy resistance. This review comprehensively compiles existing knowledge regarding the biogenesis, function, and clinical relevance of circRNAs,
Miao He +3 more
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Modulation of circRNA Metabolism by m6A Modification
Cell Reports, 2020Francesca Rossi +2 more
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iCircDA-MF: identification of circRNA-disease associations based on matrix factorization
Briefings in Bioinformatics, 2020Hang Wei
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Direct detection of circRNA in real samples using reverse transcription-rolling circle amplification
Analytica Chimica Acta, 2020Song-Mei Liu +2 more
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