Results 1 to 10 of about 19,790 (218)

Uncovering the ceRNA network and DNA methylation associated with gene expression in nasopharyngeal carcinoma [PDF]

BMC Medical Genomics, 2023
Objective This study aimed to uncover abnormally expressed genes regulated by competitive endogenous RNA (ceRNA) and DNA methylation nasopharyngeal carcinoma and to validate the role of lncRNAs in the ceRNA network on nasopharyngeal carcinoma progression.
Ting Zhang, Lu Pei, Wen-Li Qiu, Yu-xia Wei, Bi-yun Liao, Feng-lian Yang   +5 more
doaj   +2 more sources

Identification and functional analysis of a three-miRNA ceRNA network in hypertrophic scars

Journal of Translational Medicine, 2021
Background Hypertrophic scar (HTS) is a fibrotic disorder of skins and may have repercussions on the appearance as well as functions of patients. Recent studies related have shown that competitive endogenous RNA (ceRNA) networks centering around miRNAs ...
Zewei Zhang, Xin Huang, Jiahao Yang, Shuchen Gu, Yixuan Zhao, Yunhan Liu, Yimin Khoong, Shuqi Wang, Shenying Luo, Tao Zan, Guangshuai Li   +10 more
doaj   +1 more source

Bioinformatics-Based Analysis of the lncRNA-miRNA-mRNA Network and TF Regulatory Network to Explore the Regulation Mechanism in Spinal Cord Ischemia/Reperfusion Injury

Frontiers in Genetics, 2021
BackgroundSpinal cord ischemia/reperfusion injury (SCII) is a catastrophic complication involved with cardiovascular, spine, and thoracic surgeries and can lead to paraplegia.
Dan Wang, Limei Wang, Jie Han, Zaili Zhang, Bo Fang, Fengshou Chen   +5 more
doaj   +1 more source

Biomarkers mining for spinal cord injury based on integrated multi-transcriptome expression profile data

Journal of Orthopaedic Surgery and Research, 2021
Background This study was aimed to discover more biomarkers associated with spinal cord injury (SCI) by constructing a competing endogenous RNA (ceRNA) network.
Chongcheng Gong, Lin Liu, Yang Shen
doaj   +1 more source

A New Strategy to Identify ceRNA-Based CCDC144NL-AS1/SERPINE1 Regulatory Axis as a Novel Prognostic Biomarker for Stomach Adenocarcinoma via High Throughput Transcriptome Data Mining and Computational Verification

Frontiers in Oncology, 2022
Stomach adenocarcinoma (STAD) is one of the most malignant cancers that endanger human health. There is growing evidence that competitive endogenous RNA (ceRNA) regulatory networks play an important role in various human tumors.
Zhihong Huang, Xinkui Liu, Chao Wu, Shan Lu, Stalin Antony, Wei Zhou, Jingyuan Zhang, Zhishan Wu, Yingying Tan, Xiaotian Fan, Leiming You, Zhiwei Jing, Jiarui Wu   +12 more
doaj   +1 more source

Integrated analysis of the lncRNA-associated competing endogenous RNA network in salt sensitivity of blood pressure

Heliyon, 2023
Accumulating evidence showed that competing endogenous RNA (ceRNA) mechanism plays a pivotal role in salt sensitivity of blood pressure (SSBP). We constructed a ceRNA network based on SSBP-related differently expressed lncRNAs (2), mRNAs (73) and miRNAs (
Wenjuan Peng, Yunyi Xie, Juan Xia, Han Qi, Kuo Liu, Bingxiao Li, Fengxu Zhang, Fuyuan Wen, Ling Zhang   +8 more
doaj   +1 more source

Identifying a Comprehensive ceRNA Network to Reveal Novel Targets for the Pathogenesis of Parkinson's Disease

Frontiers in Neurology, 2020
Parkinson's disease (PD) is the second commonest progressive neurodegenerative disease worldwide. Increasing evidence reveals that non-coding RNAs play roles in the pathophysiological process of PD.
Xi Zhang, Xi Zhang, Shengyu Feng, Yu Fan, Yuping Luo, Lingjing Jin, Siguang Li, Siguang Li, Siguang Li   +8 more
doaj   +1 more source

Analyzing the lncRNA, miRNA, and mRNA-associated ceRNA networks to reveal potential prognostic biomarkers for glioblastoma multiforme

Cancer Cell International, 2020
Background Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNAs) act as microRNA (miRNA) sponges
Xiaolong Zhu, Lan Jiang, Hui Yang, Tianbing Chen, Xingwei Wu, Kun Lv   +5 more
doaj   +1 more source

Regulation of Long Non-coding RNA KCNQ1OT1 Network in Colorectal Cancer Immunity

Frontiers in Genetics, 2021
Over the past few decades, researchers have become aware of the importance of non-coding RNA, which makes up the vast majority of the transcriptome.
Junjie Liu, Wei Lv, Shuling Li, Jingwen Deng   +3 more
doaj   +1 more source

Comprehensive analysis of competitive endogenous RNA associated with immune infiltration in lung adenocarcinoma

Scientific Reports, 2021
To identify the prognostic biomarker of the competitive endogenous RNA (ceRNA) and explore the tumor infiltrating immune cells (TIICs) which might be the potential prognostic factors in lung adenocarcinoma.
Wenjie Chen, Wen Li, Zhenkun Liu, Guangzhi Ma, Yunfu Deng, Xiaogang Li, Zhu Wang, Qinghua zhou   +7 more
doaj   +1 more source