Results 21 to 30 of about 29,499 (226)
Age-related ceRNA networks in adult Drosophila ageing
Frontiers in Genetics, 2023 As Drosophila is an extensively used genetic model system, understanding of its regulatory networks has great significance in revealing the genetic mechanisms of ageing and human diseases. Competing endogenous RNA (ceRNA)-mediated regulation is an important mechanism by which circular RNAs (circRNAs) and long non-coding RNAs (lncRNAs) regulate ageing ...
Deying Yang +16 more
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Comprehensive ceRNA network for MACF1 regulates osteoblast proliferation
BMC Genomics, 2022 Abstract Background Previous studies have shown that microtubule actin crosslinking factor 1 (MACF1) can regulate osteoblast proliferation and differentiation through non-coding RNA (ncRNA) in bone-forming osteoblasts.
Shanfeng Jiang +5 more
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The Functional Characterization of Epigenetically Related lncRNAs Involved in Dysregulated CeRNA–CeRNA Networks Across Eight Cancer Types [PDF]
Frontiers in Cell and Developmental Biology, 2021 Numerous studies have demonstrated that lncRNAs could compete with other RNAs to bind miRNAs, as competing endogenous RNAs (ceRNAs), to regulate each other. On the other hand, ceRNAs were found to be recurrently dysregulated in cancer status. However, limited studies considered the upstream epigenetic regulatory factors that disrupted the normal ...
Dahua Xu +11 more
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Tamoxifen resistance-related ceRNA network for breast cancer
Frontiers in Cell and Developmental Biology, 2022 Background: Tamoxifen (TMX) is one of the most widely used drugs to treat breast cancer (BC). However, acquired drug resistance is still a major obstacle to its application, rendering it crucial to explore the mechanisms of TMX resistance in BC. This aims of this study were to identify the mechanisms of TMX resistance and construct ceRNA regulatory ...
Zipeng Qiao +11 more
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Scientific Reports, 2021 To identify the prognostic biomarker of the competitive endogenous RNA (ceRNA) and explore the tumor infiltrating immune cells (TIICs) which might be the potential prognostic factors in lung adenocarcinoma.
Wenjie Chen +7 more
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ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation
Frontiers in Molecular Biosciences, 2022 The competing endogenous RNA (ceRNA) network is a newly discovered post-transcriptional regulation that controls both physiological and pathological progresses. Increasing research studies have been pivoted on this theory to explore the function of novel
Yueqiang Song +4 more
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Competing Endogenous RNA Network Analysis Reveals Pivotal ceRNAs in Adrenocortical Carcinoma
Frontiers in Endocrinology, 2019 Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis.Methods: The RNA sequencing expression data of 77 ACCs in TCGA were obtained from GEPIA.
Weiwei Liang, Fangfang Sun
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Regulation of Long Non-coding RNA KCNQ1OT1 Network in Colorectal Cancer Immunity
Frontiers in Genetics, 2021 Over the past few decades, researchers have become aware of the importance of non-coding RNA, which makes up the vast majority of the transcriptome.
Junjie Liu +3 more
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BMC Medical Genomics, 2022 Research Highlights It was the first time to explore the disorder of ceRNA network involved in the pathogenesis of AIH. The co-expression relationship between the differentially expressed lncRNAs, miRNAs and mRNAs were predicted. The potential biological
Zhencheng Li +6 more
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Frontiers in Cell and Developmental Biology, 2022 The role and mechanism of inflammation in breast cancer is unclear. This study aims to probe the relationship between inflammation and long non-coding RNAs (lncRNAs) and to stablish an inflammation-related competing endogenous RNA (ceRNA) network in ...
Jingxing Liu, Shuyuan Xiao, Jing Chen
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