Results 21 to 30 of about 4,440,633 (238)
The ceRNA network of lncRNA and miRNA in lung cancer [PDF]
Genomics & Informatics, 2020 Since lung cancer is a major causative for cancer-related deaths, the investigations for discovering biomarkers to diagnose at an early stage and to apply therapeutic strategies have been continuously conducted. Recently, long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) are being exponentially studied as promising biomarkers of lung cancer ...
Seo, Danbi +3 more
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Development of Ferroptosis-Associated ceRNA Network in Periodontitis
International Dental Journal, 2023 Periodontitis is a chronic inflammatory illness that may lead to tooth loosening and even loss, and its pathogenesis is not fully understood. Ferroptosis is an iron-dependent, regulated cell death. The present study aims to find the key ferroptosis-related genes (FRGs) in periodontitis and develop an mRNA-miRNA-lncRNA network to deeply explore the ...
Churen Zhang +3 more
openaire +3 more sources
Identification and functional analysis of a three-miRNA ceRNA network in hypertrophic scars
Journal of Translational Medicine, 2021 Background Hypertrophic scar (HTS) is a fibrotic disorder of skins and may have repercussions on the appearance as well as functions of patients. Recent studies related have shown that competitive endogenous RNA (ceRNA) networks centering around miRNAs ...
Zewei Zhang +10 more
doaj +1 more source
Frontiers in Genetics, 2021 BackgroundSpinal cord ischemia/reperfusion injury (SCII) is a catastrophic complication involved with cardiovascular, spine, and thoracic surgeries and can lead to paraplegia.
Dan Wang +5 more
doaj +1 more source
Bioinformatics analysis of lncRNA‑associated ceRNA network in melanoma [PDF]
Journal of Cancer, 2021 Melanoma is an extremely malignant tumor with early metastasis and high mortality. Little is known about the process of by which melanoma occurs, as its mechanism is very complex and only limited data are available on its long non-coding RNA (lncRNA)-associated competing endogenous RNAs (ceRNAs).
Ding, Yi +5 more
openaire +2 more sources
Journal of Orthopaedic Surgery and Research, 2021 Background This study was aimed to discover more biomarkers associated with spinal cord injury (SCI) by constructing a competing endogenous RNA (ceRNA) network.
Chongcheng Gong, Lin Liu, Yang Shen
doaj +1 more source
Interactions between Distant ceRNAs in Regulatory Networks [PDF]
Biophysical Journal, 2014 Competing endogenous RNAs (ceRNAs) were recently introduced as RNA transcripts that affect each other's expression level through competition for their microRNA (miRNA) coregulators. This stems from the bidirectional effects between miRNAs and their target RNAs, where a change in the expression level of one target affects the level of the miRNA ...
Mor Nitzan +4 more
openaire +3 more sources
Comprehensive analysis of the ceRNA network in coronary artery disease [PDF]
Scientific Reports, 2021 AbstractWith the rapid aging of the population, coronary artery disease (CAD) has become one of the most fatal chronic diseases. However, the genetic mechanism of CAD is still unclear. The purpose of this study is to construct the lncRNA-miRNA-mRNA regulatory network for CAD diseases and systematically identify differentially expressed genes in ...
Weikang Bian +8 more
openaire +3 more sources
Frontiers in Oncology, 2022 Stomach adenocarcinoma (STAD) is one of the most malignant cancers that endanger human health. There is growing evidence that competitive endogenous RNA (ceRNA) regulatory networks play an important role in various human tumors.
Zhihong Huang +12 more
doaj +1 more source
Heliyon, 2023 Accumulating evidence showed that competing endogenous RNA (ceRNA) mechanism plays a pivotal role in salt sensitivity of blood pressure (SSBP). We constructed a ceRNA network based on SSBP-related differently expressed lncRNAs (2), mRNAs (73) and miRNAs (
Wenjuan Peng +8 more
doaj +1 more source