Results 21 to 30 of about 16,562 (192)

Comprehensive analysis of competitive endogenous RNA associated with immune infiltration in lung adenocarcinoma

open access: yesScientific Reports, 2021
To identify the prognostic biomarker of the competitive endogenous RNA (ceRNA) and explore the tumor infiltrating immune cells (TIICs) which might be the potential prognostic factors in lung adenocarcinoma.
Wenjie Chen   +7 more
doaj   +1 more source

ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation

open access: yesFrontiers in Molecular Biosciences, 2022
The competing endogenous RNA (ceRNA) network is a newly discovered post-transcriptional regulation that controls both physiological and pathological progresses. Increasing research studies have been pivoted on this theory to explore the function of novel
Yueqiang Song   +4 more
doaj   +1 more source

Comprehensive ceRNA network for MACF1 regulates osteoblast proliferation

open access: yesBMC Genomics, 2022
Abstract Background Previous studies have shown that microtubule actin crosslinking factor 1 (MACF1) can regulate osteoblast proliferation and differentiation through non-coding RNA (ncRNA) in bone-forming osteoblasts.
Shanfeng Jiang   +5 more
openaire   +3 more sources

Competing Endogenous RNA Network Analysis Reveals Pivotal ceRNAs in Adrenocortical Carcinoma

open access: yesFrontiers in Endocrinology, 2019
Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis.Methods: The RNA sequencing expression data of 77 ACCs in TCGA were obtained from GEPIA.
Weiwei Liang, Fangfang Sun
doaj   +1 more source

Regulation of Long Non-coding RNA KCNQ1OT1 Network in Colorectal Cancer Immunity

open access: yesFrontiers in Genetics, 2021
Over the past few decades, researchers have become aware of the importance of non-coding RNA, which makes up the vast majority of the transcriptome.
Junjie Liu   +3 more
doaj   +1 more source

Age-related ceRNA networks in adult Drosophila ageing

open access: yesFrontiers in Genetics, 2023
As Drosophila is an extensively used genetic model system, understanding of its regulatory networks has great significance in revealing the genetic mechanisms of ageing and human diseases. Competing endogenous RNA (ceRNA)-mediated regulation is an important mechanism by which circular RNAs (circRNAs) and long non-coding RNAs (lncRNAs) regulate ageing ...
Deying Yang   +16 more
openaire   +3 more sources

STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling

open access: yesJournal of Hematology & Oncology, 2018
Background Targeting cancer stem cells is critical for suppressing cancer progression and recurrence. Finding novel markers or related pathways could help eradicate or diagnose cancer in clinic.
Lufeng Zheng   +7 more
doaj   +1 more source

Construction and function analysis of the LncRNA-miRNA-mRNA competing endogenous RNA network in autoimmune hepatitis

open access: yesBMC Medical Genomics, 2022
Research Highlights It was the first time to explore the disorder of ceRNA network involved in the pathogenesis of AIH. The co-expression relationship between the differentially expressed lncRNAs, miRNAs and mRNAs were predicted. The potential biological
Zhencheng Li   +6 more
doaj   +1 more source

Identification of Potential Signatures and Their Functions for Acute Lymphoblastic Leukemia: A Study Based on the Cancer Genome Atlas

open access: yesFrontiers in Genetics, 2021
ObjectiveAcute lymphoblastic leukemia (ALL) is a malignant disease most commonly diagnosed in adolescents and young adults. This study aimed to explore potential signatures and their functions for ALL.MethodsDifferentially expressed mRNAs (DEmRNAs) and ...
Weimin Wang   +6 more
doaj   +1 more source

Construction and dissection of the ceRNA‑ceRNA network reveals critical modules in depression

open access: yesMolecular Medicine Reports, 2019
The prevalence of mental health disorders such as depression is high. Depression is a multifactorial disorder and its underlying mechanisms remain unclear. Competing endogenous RNA (ceRNA) regulation has been reported to serve important roles in human disease.
Lang, Yan, Zhang, Jingchao, Yuan, Zheng
openaire   +3 more sources

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