Results 41 to 50 of about 19,790 (218)
Frontiers in Genetics, 2021 ObjectiveAcute lymphoblastic leukemia (ALL) is a malignant disease most commonly diagnosed in adolescents and young adults. This study aimed to explore potential signatures and their functions for ALL.MethodsDifferentially expressed mRNAs (DEmRNAs) and ...
Weimin Wang +6 more
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Construction and dissection of the ceRNA‑ceRNA network reveals critical modules in depression
Molecular Medicine Reports, 2019 The prevalence of mental health disorders such as depression is high. Depression is a multifactorial disorder and its underlying mechanisms remain unclear. Competing endogenous RNA (ceRNA) regulation has been reported to serve important roles in human disease.
Lang, Yan, Zhang, Jingchao, Yuan, Zheng
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Frontiers in Cell and Developmental Biology, 2022 The role and mechanism of inflammation in breast cancer is unclear. This study aims to probe the relationship between inflammation and long non-coding RNAs (lncRNAs) and to stablish an inflammation-related competing endogenous RNA (ceRNA) network in ...
Jingxing Liu, Shuyuan Xiao, Jing Chen
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Extensive ceRNA–ceRNA interaction networks mediated by miRNAs regulate development in multiple rhesus tissues [PDF]
Nucleic Acids Research, 2016 Crosstalk between RNAs mediated by shared microRNAs (miRNAs) represents a novel layer of gene regulation, which plays important roles in development. In this study, we analyzed time series expression data for coding genes and long non-coding RNAs (lncRNAs) to identify thousands of interactions among competitive endogenous RNAs (ceRNAs) in four rhesus ...
Xu, Juan +14 more
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Chemoresistance Mediated by ceRNA Networks Associated With the PVT1 Locus [PDF]
Frontiers in Oncology, 2019 Competitive endogenous RNA (ceRNA) networks have emerged as critical regulators of carcinogenesis. Their activity is mediated by various non-coding RNAs (ncRNAs), including long non-coding RNAs and microRNAs, which competitively bind to targets, thereby modulating gene expression and activity of proteins.
Olorunseun O. Ogunwobi +2 more
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Construction of a lncRNA–miRNA–mRNA ceRNA network. [PDF]
, 2021 (A) Volcano map of 69 significant DElncRNAs. (B) Correlation between the five prognostic mRNAs and their corresponding miRNAs. (C) A ceRNA network was constructed containing five mRNAs, three miRNAs, and 69 lncRNAs for NSCLC prognosis.
Jie-Tao Lin (9377048) +10 more
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Integrative Clustering Reveals a Novel Subtype of Soft Tissue Sarcoma With Poor Prognosis
Frontiers in Genetics, 2020 BackgroundSoft tissue sarcomas (STSs) are heterogeneous at the clinical and molecular level and need to be further sub-clustered for treatment and prognosis.Materials And MethodsSTSs were sub-clustered based on RNAseq and miRNAseq data extracted from The
Zhenhua Zhu +4 more
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A ceRNA network mediated by LINC00475 in papillary thyroid carcinoma
Open Medicine, 2021 Abstract Papillary thyroid carcinoma (PTC) is the most frequent histological type of differentiated thyroid carcinoma. Long noncoding RNAs (lncRNAs) have been widely reported to play a key role in human malignancies, and PTC is included. This study aimed to find out the functions and mechanism of lncRNA LINC00475 in PTC.
Yang Yarong +5 more
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The flowchart of ceRNA network analysis. [PDF]
, 2019 The flowchart of ceRNA network analysis.
Wei-dong Jiang (7114763) +1 more
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