Results 41 to 50 of about 16,562 (192)
Tamoxifen resistance-related ceRNA network for breast cancer
Frontiers in Cell and Developmental Biology, 2022 Background: Tamoxifen (TMX) is one of the most widely used drugs to treat breast cancer (BC). However, acquired drug resistance is still a major obstacle to its application, rendering it crucial to explore the mechanisms of TMX resistance in BC. This aims of this study were to identify the mechanisms of TMX resistance and construct ceRNA regulatory ...
Zipeng Qiao +11 more
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Comprehensive analysis of ceRNA network of ERCC4 in colorectal cancer
PeerJ, 2021 Objective ERCC4 is one of the most significant molecules of Nucleotide Excision Repair (NER), which has been researched due to its high expression in colorectal cancer (CRC). This study aimed to find out the ceRNA (competitive endogenous RNA) network of ERCC4 in CRC.
Hu, Huixin +5 more
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Frontiers in Genetics, 2021 AimsActivation of cardiac fibroblasts (CF) is crucial to cardiac fibrosis. We constructed a cardiac fibroblast-related competing endogenous RNA (ceRNA) network.
Qing-Yuan Gao +19 more
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The regulatory mechanism of LncRNA-mediated ceRNA network in osteosarcoma
Scientific Reports, 2022 AbstractAberrantly expressed lncRNAs have been reported to be closely related to the oncogenesis and development of osteosarcoma. However, the role of a dysregulated lncRNA-miRNA-mRNA network in osteosarcoma in the same individual needs to be further investigated. Whole transcriptome sequencing was performed on the tumour tissues and matched paratumour
Chengsen Lin +10 more
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BMC Medical Genomics, 2022 Background Being the most common arrhythmia in clinic, atrial fibrillation (AF) causes various comorbidities to patients such as heart failure and stroke.
Xi Chen, Xiang-Yu He, Qing Dan, Yang Li
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Translational Oncology, 2022 Background: Increasing numbers of studies have elucidated the role of competitive endogenous RNA (ceRNA) networks in carcinogenesis. However, the potential role of the paclitaxel-related ceRNA network in the innate mechanism and prognosis of pancreatic ...
Si Yuan Lu +9 more
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Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks [PDF]
Genome Research, 2014 We introduce a method for simultaneous prediction of microRNA–target interactions and their mediated competitive endogenous RNA (ceRNA) interactions. Using high-throughput validation assays in breast cancer cell lines, we show that our integrative approach significantly improves on microRNA–target prediction accuracy as assessed by both mRNA and ...
Chiu HS +16 more
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A Potential ceRNA Network for Neurological Damage in Preterm Infants
BioMed Research International, 2021 Objective. This study is aimed at identifying key genes involved in neurological damage in preterm infants and at determining their potential circRNA‐miRNA‐mRNA regulatory mechanisms. Methods. Differentially expressed miRNAs, mRNAs, and circRNAs were downloaded from the GEO database.
Jin Huang, Xuejing Liang, Zhenyu Cai
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Construction and Analysis of the Tumor-Specific mRNA–miRNA–lncRNA Network in Gastric Cancer
Frontiers in Pharmacology, 2020 Weighted correlation network analysis (WGCNA) is a statistical method that has been widely used in recent years to explore gene co-expression modules.
Xiaohao Zheng +8 more
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Journal of Inflammation Research, 2021 Chenglin Ye,1 Sizhe Zhu,2 Jingping Yuan1 1Department of Pathology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Department of Clinical Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences
Ye C, Zhu S, Yuan J
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