Results 51 to 60 of about 4,583,316 (255)
, 2021 (A) An integrative pipeline for transcriptome-wide identification of lincRNA-miRNA-mRNA regulatory networks. Interactions between miRNAs and their targets are predicted using three computational approaches (miRanda, PITA and RNAhybrid). miRNA-lincRNA and
Jiaxing Chen (9107364) +13 more
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Integrative Clustering Reveals a Novel Subtype of Soft Tissue Sarcoma With Poor Prognosis
Frontiers in Genetics, 2020 BackgroundSoft tissue sarcomas (STSs) are heterogeneous at the clinical and molecular level and need to be further sub-clustered for treatment and prognosis.Materials And MethodsSTSs were sub-clustered based on RNAseq and miRNAseq data extracted from The
Zhenhua Zhu +4 more
doaj +1 more source
Construction of a lncRNA–miRNA–mRNA ceRNA network.
, 2021 (A) Volcano map of 69 significant DElncRNAs. (B) Correlation between the five prognostic mRNAs and their corresponding miRNAs. (C) A ceRNA network was constructed containing five mRNAs, three miRNAs, and 69 lncRNAs for NSCLC prognosis.
Jie-Tao Lin (9377048) +10 more
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Frontiers in Cardiovascular Medicine, 2022 BackgroundAccumulated studies have revealed that long non-coding RNAs (lncRNAs) play critical roles in human diseases by acting as competing endogenous RNAs (ceRNAs).
Xiangyu Ke +8 more
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CeRNA regulatory network in alcohol-related EC progression.
, 2022 The lncRNA–miRNA interactions, and miRNA-target gene interactions were integrated as lncRNA-miRNA-target genes interactions, and ceRNA network was visualized based on lncRNA-miRNA-target genes interactions. A. The ceRNA network constructed by the DEGs in
Ren-Dong Xiao (12878506) +5 more
core +1 more source
Frontiers in Bioengineering and Biotechnology, 2019 Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most common form of dementia in old age. The complexity and behavior of circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network remained poorly ...
Yan Zhang, Fulong Yu, Siqi Bao, Jie Sun
doaj +1 more source
Heliyon, 2022 Background: Hepatitis C virus (HCV) infection contribute to liver fibrosis and cirrhosis, which significantly increases the risk of hepatocellular carcinoma (HCC) development.
Lishi Shao +3 more
doaj +1 more source
A ceRNA network mediated by LINC00475 in papillary thyroid carcinoma
Open Medicine, 2021 Abstract Papillary thyroid carcinoma (PTC) is the most frequent histological type of differentiated thyroid carcinoma. Long noncoding RNAs (lncRNAs) have been widely reported to play a key role in human malignancies, and PTC is included. This study aimed to find out the functions and mechanism of lncRNA LINC00475 in PTC.
Yang Yarong +5 more
openaire +3 more sources
High-throughput validation of ceRNA regulatory networks
BMC Genomics, 2017 Background: MicroRNAs (miRNAs) play multiple roles in tumor biology [1]. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration [2]. Specifically, computational models predicted [3, 4] and experimental assays confirmed [5, 6] that miRNA activity is dependent on miRNA target
Hua-Sheng Chiu +7 more
openaire +4 more sources
Comprehensive ceRNA network for MACF1 regulates osteoblast proliferation
BMC Genomics, 2022 Abstract Background Previous studies have shown that microtubule actin crosslinking factor 1 (MACF1) can regulate osteoblast proliferation and differentiation through non-coding RNA (ncRNA) in bone-forming osteoblasts.
Shanfeng Jiang +5 more
openaire +3 more sources