Results 51 to 60 of about 16,562 (192)

The Construction and Analysis of a ceRNA Network Related to Salt‐Sensitivity Hypertensives

BioMed Research International, 2022
Background. Salt‐sensitivity hypertensives (SSH) are an independent risk factor for cardiovascular disease. However, the mechanism of SSH is not clear. This study is aimed at constructing a competing endogenous RNA (ceRNA) network related to SSH. Methods.
Xiu-Juan Liu, Hong-Lin Yin, Yan Li, Hao Hao, Yang Liu, Quan-Lin Zhao   +5 more
openaire   +2 more sources

Comprehensive Construction of a Circular RNA-Associated Competing Endogenous RNA Network Identified Novel Circular RNAs in Hypertrophic Cardiomyopathy by Integrated Analysis

Frontiers in Genetics, 2020
Hypertrophic cardiomyopathy (HCM), the most common heritable cardiomyopathy, is associated with a high risk of sudden cardiac death. The complexity and behavior of the circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network in HCM have
Qi Guo, Qi Guo, Junjie Wang, Junjie Wang, Runlu Sun, Runlu Sun, Zhijian He, Zhijian He, Qian Chen, Qian Chen, Wenhao Liu, Wenhao Liu, Maoxiong Wu, Maoxiong Wu, Jinlan Bao, Jinlan Bao, Zhaoyu Liu, Zhaoyu Liu, Jingfeng Wang, Jingfeng Wang, Yuling Zhang, Yuling Zhang   +21 more
doaj   +1 more source

Circular RNA-related CeRNA network and prognostic signature for patients with oral squamous cell carcinoma

Frontiers in Pharmacology, 2022
Background: Circular RNA (circRNA) has an important influence on oral squamous cell carcinoma (OSCC) progression as competing endogenous RNAs (ceRNAs). However, the link between ceRNAs and the OSCC immune microenvironment is unknown.
Yaodong He, Dengcheng Yang, Yunshan Li, Junwei Xiang, Liecheng Wang, Yuanyin Wang   +5 more
doaj   +1 more source

Identification of hub genes and prediction of the ceRNA network in adult sepsis. [PDF]

PeerJ
Background Sepsis refers to a dysregulated host immune response to infection. It carries a high risk of morbidity and mortality, and its pathogenesis has yet to be fully elucidated. The main aim of this study was to identify prognostic hub genes for sepsis and to predict a competitive endogenous RNA (ceRNA) network that ...
Xue K, Wu K, Luo H, Luo H, Zhong Z, Li F, Li L, Chen L.   +7 more
europepmc   +3 more sources

Construction of a lncRNA-associated competing endogenous RNA regulatory network after traumatic brain injury in mouse

Molecular Brain, 2022
Traumatic brain injury (TBI) is a major public health problem worldwide which causes high mortality and disability. Functioning as microRNA (miRNA) sponges, long non-coding RNA (lncRNA) regulates the expression of protein-coding genes in a competing ...
Siqi Wang, Yiyu Sun, Shaobo Hu, Cen Lou, Yuan-Bo Pan   +4 more
doaj   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Identification of CeRNA Regulatory Networks in Atrial Fibrillation Using Nanodelivery

Evidence-Based Complementary and Alternative Medicine, 2022
The initiation and maintenance of AF is a complex biological process that is the ultimate manifestation of many cardiovascular diseases. And the pathogenesis of atrial fibrillation (AF) is unclear. Therefore, this study aimed to find the potential competing endogenous RNAs (ceRNAs) network and molecular dysregulation mechanism associated with AF ...
Ping Lin, Lingqiang Meng, Lei Lyu
openaire   +2 more sources

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

Animal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang, Qiuyang Li, Zhiying Wang, Shan Zhang, Kassahun Bekana, Qingfeng Zhang, Juanshan Zheng, Hongwei Xu, Xianyong Lan, Chuanying Pan   +9 more
wiley   +1 more source

Circular RNAs and competing endogenous RNA (ceRNA) networks

Translational Cancer Research, 2018
In recent years, advances in bioinformatics approaches have allowed a systematic characterization of circular RNAs (circRNAs) across a variety of cell types. Demonstration of cell type specificity, regulated expression, and conservation between species all suggest that circRNAs have functional importance.
Apratim, Mitra, Karl, Pfeifer, Ki-Sun, Park   +2 more
openaire   +2 more sources

Construction and analysis of pseudogene-related ceRNA network in breast cancer

Scientific Reports, 2023
AbstractBreast cancer (BC) is one of the leading causes of cancer-related deaths in women. The present study explored the potential role of pseudogenes in BC via construction and analysis of a competing endogenous RNA (ceRNA) network through a three-step process. First, we screened differentially expressed genes in nine BC datasets.
Hossein Mohebifar, Amir Sabbaghian, Touraj Farazmandfar, Masoud Golalipour   +3 more
openaire   +3 more sources