Results 71 to 80 of about 19,790 (218)

Comprehensive analysis of ceRNA network related to lincRNA in glioblastoma and prediction of clinical prognosis

BMC Cancer, 2021
Background Long intergenic non-coding RNAs (lincRNAs) are capable of regulating several tumours, while competitive endogenous RNA (ceRNA) networks are of great significance in revealing the biological mechanism of tumours.
Guangdong Liu, Danian Liu, Jingjing Huang, Jianxin Li, Chuang Wang, Guangyao Liu, Shiqiang Ge, Haidong Gong   +7 more
doaj   +1 more source

Integrated Analysis of the lncRNA-Associated ceRNA Network in Wilms Tumor via TARGET and GEO Databases [PDF]

, 2022
Wilms tumor (WT) is the most common genitourinary renal tumor that typically occurs in children under 15 and is thought to be linked to somatic and germline mutations.
An, Biao, Liang, Xiao, Biao An, Hu, Yuan, Xiao Liang, Yuan Hu   +5 more
core   +1 more source

Circular RNA-related CeRNA network and prognostic signature for patients with oral squamous cell carcinoma

Frontiers in Pharmacology, 2022
Background: Circular RNA (circRNA) has an important influence on oral squamous cell carcinoma (OSCC) progression as competing endogenous RNAs (ceRNAs). However, the link between ceRNAs and the OSCC immune microenvironment is unknown.
Yaodong He, Dengcheng Yang, Yunshan Li, Junwei Xiang, Liecheng Wang, Yuanyin Wang   +5 more
doaj   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Identification of CeRNA Regulatory Networks in Atrial Fibrillation Using Nanodelivery

Evidence-Based Complementary and Alternative Medicine, 2022
The initiation and maintenance of AF is a complex biological process that is the ultimate manifestation of many cardiovascular diseases. And the pathogenesis of atrial fibrillation (AF) is unclear. Therefore, this study aimed to find the potential competing endogenous RNAs (ceRNAs) network and molecular dysregulation mechanism associated with AF ...
Ping Lin, Lingqiang Meng, Lei Lyu
openaire   +2 more sources

Integrated analysis of lncRNA-associated ceRNA network reveals potential biomarkers for the prognosis of hepatitis B virus-related hepatocellular carcinoma [PDF]

, 2019
Hongyan Li, Xiaonan Zhao, Chenghua Li, Chuanlun Sheng, Zhenzi Bai Infectious Department, China-Japan Union Hospital, Jilin University, Changchun 130033, China Background: There is evidence that abnormal expression of lncRNAs is associated with hepatitis ...
Li H, Li C, Bai Z, Sheng C, Zhao X
core  

Integrated Bioinformatics and Validation of lncRNA-Mediated ceRNA Network in Myocardial Ischemia/Reperfusion Injury [PDF]

, 2022
BACKGROUND: Myocardial ischemia/reperfusion (MI/R) injury is a common pathology in ischemia heart disease. Long noncoding RNAs (lncRNAs) are significant regulators related to many ischemia/reperfusion conditions.
Wenqin Cai, Min Pan, Cai, Wenqin, Gong Jin, Zhoufei Fang, Lu, Dan, Pan, Min, Dan Lu, Xu, Changsheng, Jin, Gong, Han, Ying, Changsheng Xu, Fang, Zhoufei, Ying Han   +13 more
core   +1 more source

Comprehensive analysis of the FOXA1-related ceRNA network and identification of the MAGI2-AS3/DUSP2 axis as a prognostic biomarker in prostate cancer

Frontiers in Oncology, 2023
BackgroundProstate cancer (PCa) is the second most common cause of cancer-related deaths in American men. Even though increasing evidence has disclosed the competitive endogenous RNA (ceRNA) regulatory networks among cancers, the complexity and behavior ...
Guo Yang, Xiong Chen, Zhen Quan, Miao Liu, Yuan Guo, Yangbin Tang, Lang Peng, Leilei Wang, Yingying Wu, Xiaohou Wu, Jiayu Liu, Yongbo Zheng   +11 more
doaj   +1 more source

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

Animal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang, Qiuyang Li, Zhiying Wang, Shan Zhang, Kassahun Bekana, Qingfeng Zhang, Juanshan Zheng, Hongwei Xu, Xianyong Lan, Chuanying Pan   +9 more
wiley   +1 more source

Circular RNAs and competing endogenous RNA (ceRNA) networks

Translational Cancer Research, 2018
In recent years, advances in bioinformatics approaches have allowed a systematic characterization of circular RNAs (circRNAs) across a variety of cell types. Demonstration of cell type specificity, regulated expression, and conservation between species all suggest that circRNAs have functional importance.
Apratim, Mitra, Karl, Pfeifer, Ki-Sun, Park   +2 more
openaire   +2 more sources