Results 71 to 80 of about 29,499 (226)
The Nefarious Nexus of Noncoding RNAs in Cancer [PDF]
, 2018 The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts.
Anastasiadou, Eleni +3 more
core +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
A ceRNA network mediated by LINC00475 in papillary thyroid carcinoma
Open Medicine, 2021 Abstract Papillary thyroid carcinoma (PTC) is the most frequent histological type of differentiated thyroid carcinoma. Long noncoding RNAs (lncRNAs) have been widely reported to play a key role in human malignancies, and PTC is included. This study aimed to find out the functions and mechanism of lncRNA LINC00475 in PTC.
Yang Yarong +5 more
openaire +3 more sources
Integrated Analysis of lncRNA–Mediated ceRNA Network in Lung Adenocarcinoma [PDF]
Frontiers in Oncology, 2020 A growing body of evidence indicates that long non-coding RNAs (lncRNAs) can act as competitive endogenous RNAs (ceRNAs) to bind to microRNAs (miRNAs), thereby affecting and regulating the expression of target genes. The lncRNA-miRNA-mRNA ceRNA network has been theorized to play an indispensable role in many types of tumors.
Xianxian Wu +4 more
openaire +3 more sources
Animal Research and One Health, EarlyView.This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang +9 more
wiley +1 more source
JAMI: fast computation of conditional mutual information for ceRNA network analysis [PDF]
Bioinformatics, 2018 Abstract Motivation Genome-wide measurements of paired miRNA and gene expression data have enabled the prediction of competing endogenous RNAs (ceRNAs). It has been shown that the sponge effect mediated by protein-coding as well as non-coding ceRNAs can play an important regulatory role in the cell in
Andrea Hornakova +3 more
openaire +3 more sources
Integrated analysis of circRNA-associated ceRNA network in ischemic stroke
Frontiers in Genetics, 2023 Introduction: Stroke, of which ischemic stroke (IS) is the major type, is the second leading cause of disability and death worldwide. Circular RNAs (circRNAs) are reported to play important role in the physiology and pathology of IS. CircRNAs often act as competing endogenous RNA (ceRNA) to regulate gene expression by acting as miRNA sponges.
Rongli Fan +6 more
openaire +3 more sources
Parent-child communication about internet use and acceptance of parental authority
, 2020 Structural equation modeling is applied to investigate how parents' communication with their child about his or her Internet use is linked to the child's acceptance of parental authority in the context of Internet use, and how this in turn is linked to ...
Ponnet, Koen +4 more
core +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT This paper examines how sustainable human resource management (SHRM) influences employee engagement and performance through distinct cognitive and relational mechanisms. While previous research has demonstrated positive associations between SHRM and employee outcomes, the processes through which these effects occur remain insufficiently ...
Daniel Roque Gomes +4 more
wiley +1 more source
Bioinformatics Analysis of ceRNA Network Related to Polycystic Ovarian Syndrome
Computational and Mathematical Methods in Medicine, 2021 Introduction. Polycystic ovary syndrome (PCOS) is caused by the hormonal environment in utero, abnormal metabolism, and genetics, and it is common in women of childbearing age. A large number of studies have reported that lncRNA is important to the biological process of cancer and can be used as a potential prognostic biomarker.
Yuanqi Li, Yong Tan
openaire +2 more sources