Results 81 to 90 of about 4,440,633 (238)
Identification of CeRNA Regulatory Networks in Atrial Fibrillation Using Nanodelivery
Evidence-Based Complementary and Alternative Medicine, 2022 The initiation and maintenance of AF is a complex biological process that is the ultimate manifestation of many cardiovascular diseases. And the pathogenesis of atrial fibrillation (AF) is unclear. Therefore, this study aimed to find the potential competing endogenous RNAs (ceRNAs) network and molecular dysregulation mechanism associated with AF ...
Ping Lin, Lingqiang Meng, Lei Lyu
openaire +2 more sources
Frontiers in Oncology, 2023 BackgroundProstate cancer (PCa) is the second most common cause of cancer-related deaths in American men. Even though increasing evidence has disclosed the competitive endogenous RNA (ceRNA) regulatory networks among cancers, the complexity and behavior ...
Guo Yang +11 more
doaj +1 more source
Image1_Integrated analysis of circRNA-associated ceRNA network in ischemic stroke.JPEG
, 2023 Introduction: Stroke, of which ischemic stroke (IS) is the major type, is the second leading cause of disability and death worldwide. Circular RNAs (circRNAs) are reported to play important role in the physiology and pathology of IS.
Maiqiu Wang (11821886) +5 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen +7 more
wiley +1 more source
Construction and analysis of pseudogene-related ceRNA network in breast cancer
Scientific Reports, 2023 AbstractBreast cancer (BC) is one of the leading causes of cancer-related deaths in women. The present study explored the potential role of pseudogenes in BC via construction and analysis of a competing endogenous RNA (ceRNA) network through a three-step process. First, we screened differentially expressed genes in nine BC datasets.
Hossein Mohebifar +3 more
openaire +3 more sources
Molecular Brain, 2022 Traumatic brain injury (TBI) is a major public health problem worldwide which causes high mortality and disability. Functioning as microRNA (miRNA) sponges, long non-coding RNA (lncRNA) regulates the expression of protein-coding genes in a competing ...
Siqi Wang +4 more
doaj +1 more source
Animal Research and One Health, EarlyView.This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang +9 more
wiley +1 more source
Circular RNAs and competing endogenous RNA (ceRNA) networks
Translational Cancer Research, 2018 In recent years, advances in bioinformatics approaches have allowed a systematic characterization of circular RNAs (circRNAs) across a variety of cell types. Demonstration of cell type specificity, regulated expression, and conservation between species all suggest that circRNAs have functional importance.
Apratim, Mitra +2 more
openaire +2 more sources
PLoS ONEHepatic ischemia-reperfusion injury (HIRI) is a common complication in liver surgery and transplantation. Recent studies have revealed the significant role of the competing endogenous RNA (ceRNA) network in HIRI.
Lirong Liu +5 more
doaj +1 more source