Results 101 to 110 of about 16,562 (192)

Introduction of LPIN1 as a potential diagnostic and prognostic biomarker for gastric cancer via integrative bioinformatics analysis of a competing endogenous RNA network and experimental validation [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Identification of effective biomarkers is crucial for the heterogeneous disease of gastric cancer (GC). Recent studies have focused on the role of pseudogenes regulating gene expression through competing endogenous RNA (ceRNA) networks ...
Milad Daneshmand-Parsa, Parvaneh Nikpour
doaj   +1 more source

Gastric Cancer: Pathobiology and Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
Gastric cancer is a multistep process driven by the interplay of microbial virulence, host epithelial injury, and evolving molecular reprogramming. Initiation involves pathogen‐induced epigenetic alterations and the early subversion of key oncogenic signaling networks, facilitating the transition from chronic injury to metaplasia and malignant ...
Ruixian Yu, Miao Zhang, Yan Meng, Chunxiao Zhu, Weihong Zhang, Hui Zhang, Zhifa Cao, Meihang Du, Zhangting Zhao, Junping Bai, Yi Han, Yang Tang, Wei Kang, Ka Fai To, Shi Jiao, Liwei An, Zhaocai Zhou   +16 more
wiley   +1 more source

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou, Sheng He, Lili He, Kun Liu, Wen Tang, Deming Wang, Jing Gui, Zhiying Zeng, Yan Wang, Wenjie Liu, Ren Jing   +10 more
wiley   +1 more source

Identification of Prognostic Factors Related to Super Enhancer-Regulated ceRNA Network in Metastatic Lung Adenocarcinoma

International Journal of General Medicine, 2021
Mingjiang Li,1 Bo Yang,1 Xiaoping Li,1 Haixia Ren,2 Liang Zhang,1 Lei Li,1 Wei Li,1 Xuhui Wang,1 Honggang Zhou,3 Weidong Zhang1 1Department of Thoracic Surgery, Tianjin First Central Hospital, Tianjin, People’s Republic of China; 2Department of Pharmacy,
Li M, Yang B, Li X, Ren H, Zhang L, Li L, Li W, Wang X, Zhou H, Zhang W   +9 more
doaj  

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source

Screening of prognostic biomarkers for endometrial carcinoma based on a ceRNA network

PeerJ, 2018
Objective This study aims to reveal the regulation network of lncRNAs-miRNAs-mRNA in endometrial carcinoma (EC), to investigate the underlying mechanisms of EC occurrence and progression, to screen prognostic biomarkers.
Zheng, Ming-Jun, Gou, Rui, Zhang, Wen-Chao, Nie, Xin, Wang, Jing, Gao, Ling-Ling, Liu, Juan-Juan, Li, Xiao, Lin, Bei   +8 more
openaire   +3 more sources

Platform competition and strategic trade‐offs for complementors: Heterogeneous reactions to the entry of a new platform

Strategic Management Journal, Volume 47, Issue 6, Page 1671-1729, June 2026.
Abstract Research Summary We study how the entry of a rival platform affects the strategies of the incumbent's complementors. The latter face a trade‐off: While the entry threatens their benefits from indirect network effects, it also allows them to escape intense within‐platform competition.
Johannes Loh, Ambre Elsas‐Nicolle
wiley   +1 more source

Roles of the competitive endogenous RNA network in chronic renal failure and research progress in traditional Chinese medicine interventions

Xin yixue
Chronic renal failure (CRF) is associated with multiple complications, a poor prognosis, and limited therapeutic options. Recent studies have shown that the competitive endogenous RNA (ceRNA) network mediated by long non-coding RNAs (lncRNAs) and ...
Jiayuan LI, Jian ZHONG, Mouying DU, Qinke LÜ, Xiaodong SHI   +4 more
doaj   +1 more source

ceRNA networks in ischemic stroke: a bibliometric analysis

Egyptian Journal of Medical Human Genetics
Abstract Background and method Ischemic stroke, a leading cause of death and disability worldwide, has been increasingly linked to ceRNA networks, which regulate neuronal damage and recovery. Despite growing interest, a comprehensive bibliometric analysis of ceRNA’s role in stroke remains limited.
Loo Keat Wei, Lyn R. Griffiths, Trygve O. Tollefsbol   +2 more
openaire   +2 more sources

The Analysis of ceRNA Networks and Tumor Microenvironment in Endometrial Cancer

Journal of Cancer
Background: Endometrial carcinoma is a life-threatening and aggressive tumor that affects women worldwide. ceRNAs and carcinoma-infiltrating immunocytes can be associated with tumor formation and progression. Therefore, investigating the unique mechanisms underlying endometrial carcinoma is crucial.
Huang, Jian, Yang, Xiaoyue, Xu, Shen, Li, Ping   +3 more
openaire   +2 more sources