Results 101 to 110 of about 29,499 (226)

Platform competition and strategic trade‐offs for complementors: Heterogeneous reactions to the entry of a new platform

open access: yesStrategic Management Journal, EarlyView.
Abstract Research Summary We study how the entry of a rival platform affects the strategies of the incumbent's complementors. The latter face a trade‐off: While the entry threatens their benefits from indirect network effects, it also allows them to escape intense within‐platform competition.
Johannes Loh, Ambre Elsas‐Nicolle
wiley   +1 more source

Chemoresistance Mediated by ceRNA Networks Associated With the PVT1 Locus [PDF]

open access: yesFrontiers in Oncology, 2019
Competitive endogenous RNA (ceRNA) networks have emerged as critical regulators of carcinogenesis. Their activity is mediated by various non-coding RNAs (ncRNAs), including long non-coding RNAs and microRNAs, which competitively bind to targets, thereby modulating gene expression and activity of proteins.
Olorunseun O. Ogunwobi   +2 more
openaire   +3 more sources

Using Boolean Networks to Model Post-transcriptional Regulation in Gene Regulatory Networks [PDF]

open access: yes, 2012
In Gene Regulatory Networks research there is a considerable lack of tech- niques and tools to understand these networks from a System Biology point of view. The typical biological approach is to reconstruct a particular network from expression patterns,
Benso, Alfredo   +4 more
core  

Putative involvement of lncRNA, miRNA, and mRNA‐mediated ceRNA network regulation in drought priming to enhance drought tolerance in Nicotiana tabacum

open access: yesAnnals of Applied Biology, EarlyView.
Drought priming increased the tolerance of Nicotiana tabacum to severe, recurring drought stress by modulating the expression of stress‐related genes via long non‐coding RNAs (lncRNAs), which acted as competing endogenous RNAs (ceRNAs) for microRNAs (miRNAs) and messenger RNAs (mRNAs).
Fatma Aydinoglu, Elif Yalvac
wiley   +1 more source

MicroRNAs in the stressed heart: Sorting the signal from the noise [PDF]

open access: yes, 2014
The short noncoding RNAs, known as microRNAs, are of undisputed importance in cellular signaling during differentiation and development, and during adaptive and maladaptive responses of adult tissues, including those that comprise the heart.
Matkovich, Scot J
core   +3 more sources

Evaluating putative lncRNA‐mediated ceRNA regulatory network involving miR396 and miR319 in maize leaf growth under Fusarium verticillioides infection

open access: yesAnnals of Applied Biology, EarlyView.
The final leaf length of maize (Zea mays) was reduced due to the pathogenic fungus Fusarium verticillioides infection as a result of increased expression of miR396 in the elongation zone and decreased expression of miR319 in the mature zone of maize leaves, leading to antagonistic regulation of the expression of the GRF15 and TCP38, respectively ...
Erdem Emre Deligoz, Fatma Aydinoglu
wiley   +1 more source

Comprehensive analysis of lncRNA-miRNA-mRNA ceRNA network in ischemic stroke

open access: yesHeliyon
Objective: Competitive endogenous RNA (ceRNA) networks have uncovered a novel mode of RNA interaction, and are implicated in various biological processes and the pathogenesis of IS.
Lin Cheng, Yun Zhao, Hong Ke
doaj   +1 more source

Epigenetic dysregulation in chronic myeloid leukaemia: A myriad of mechanisms and therapeutic options [PDF]

open access: yes, 2018
The onset of global epigenetic changes in chromatin that drive tumor proliferation and heterogeneity is a hallmark of many forms cancer. Identifying the epigenetic mechanisms that govern these changes and developing therapeutic approaches to modulate ...
Koschmieder, Steffen, Vetrie, David
core   +1 more source

Peri‐Implantitis and Periodontitis: Biological Convergence, Contextual Divergence

open access: yesJournal of Periodontal Research, EarlyView.
Periodontal and peri‐implant tissues differ and coincide in many aspects, from the clinical and radiological perspective, including histology, microbiology, and molecular markers. Thus, health and disease may also follow different and similar routes.
Pablo Galindo‐Moreno   +6 more
wiley   +1 more source

NeuroPod: a real-time neuromorphic spiking CPG applied to robotics [PDF]

open access: yes, 2022
Initially, robots were developed with the aim of making our life easier, carrying out repetitive or dangerous tasks for humans. Although they were able to perform these tasks, the latest generation of robots are being designed to take a step further ...
Domínguez Morales, Juan Pedro   +3 more
core  

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