Results 121 to 130 of about 4,440,633 (238)

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Éthique de la recherche en robotique: Rapport n° 1 de la CERNA Commission de réflexion sur l’Éthique de la Recherche en sciences et technologies du Numérique d’Allistene

, 2014
La robotique, comme plus largement le numérique, débouche sur de multiples usages aux déploiements parfois aussi massifs qu’inattendus, tel l’essor actuel des drones civils. Dans ce contexte évolutif, il serait vain d’énoncer de nouvelles normes éthiques
Collectif, Cerna
core   +2 more sources

Validation of prognostic RNAs involved in ceRNA network.

, 2019
Validation of prognostic RNAs involved in ceRNA network.
Zaiye Li (6752435), Yongxiang Yuan (6752438), Canhua Jiang (624741)   +2 more
core   +1 more source

Identification of a Circular RNA as a Potential Diagnostic and Prognostic Biomarker in Breast Cancer Through Integrated Bioinformatic and Experimental Analyses

Analytical Science Advances, Volume 7, Issue 2, December 2026.
Forty circular RNAs were found to be significantly dysregulated in microarray datasets. Expression levels of hsa_circ_0000231 were significantly upregulated in breast cancer (BC) tissues, while hsa_circ_0011385 exhibited no significant difference in expression levels. This study also revealed that hsa_circ_0000231/hsa‐miR‐5683/CCNB1 regulatory axis may
MohamadReza Hashemi, Pejman Morovat, Azin Khoshghiafeh, Novin Nikbakhsh, Mohamadreza Ahmadifard   +4 more
wiley   +1 more source

Integrated Analysis of lncRNA–miRNA–mRNA ceRNA Network in Order to Discover Potential Novel Biomarkers in Stomach Cancer

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Stomach cancer (SC) or gastric cancer (GC) is one of the most common gastrointestinal malignancies. Currently, some studies based on competing endogenous RNAs (ceRNA) network analysis have been assessed for this cancer. The construction and analysis of ceRNA network is a novel approach for identification of RNA‐based biomarkers in cancer ...
Habib MotieGhader, Seyed Mehdi Jazayeri, Reyhaneh Sadat Jazayeri   +2 more
wiley   +1 more source

Whole transcriptome sequencing identifies a competitive endogenous RNA network that regulates the immunity of bladder cancer

Heliyon
Several types of non-coding RNAs such as circRNAs, lncRNAs, and miRNAs have been identified to regulate mRNAs through the mechanism known as the competitive endogenous RNA (ceRNA) network. To explore the role of the ceRNA regulatory network in the immune
Sanhe Liu, Yiqi Wang, Liqun Duan, Diansheng Cui, Kangli Deng, Zhiqiang Dong, Shaozhong Wei   +6 more
doaj   +1 more source

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, Volume 101, Issue 5, Page 2214-2239, October 2026.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Transcriptomic profiling reveals conserved stage‐associated programs across gastrointestinal adenocarcinomas

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Abstract Background Gastrointestinal (GI) adenocarcinomas exhibit substantial molecular heterogeneity despite their shared epithelial origin and anatomical continuity. Whether these anatomically distinct cancers share conserved transcriptomic programs associated with pathological stage remains unclear.
Wynston Jay Abenojar, Ron Jacob Avila, Po‐Wei Tsai, Lemmuel Tayo   +3 more
wiley   +1 more source

An Integrated Analysis of Manganese Metabolism‐Related Genes and Their Association With Biomarkers, Immune Infiltration, and Clinical Subtypes in Alzheimer's Disease

Genes, Brain and Behavior, Volume 25, Issue 5, October 2026.
This study investigates the role of manganese metabolism in Alzheimer's disease (AD) pathogenesis. Using integrated bioinformatics and machine learning, four core manganese‐related diagnostic genes (TSPO, PTBP1, GLO1, ACACB) were identified, showing high diagnostic accuracy. The analysis also revealed significant immune microenvironment alterations and
Shengnan Shu, Jiahao Hu, Shanshan Hu, Yefeng Yao   +3 more
wiley   +1 more source

Construction of ceRNA regulatory networks for active pulmonary tuberculosis

Scientific Reports
AbstractDelayed diagnosis in patients with pulmonary tuberculosis (PTB) often leads to serious public health problems. High throughput sequencing was used to determine the expression levels of lncRNAs, mRNAs, and miRNAs in the lesions and adjacent health lung tissues of patients with PTB.
Qifeng Li, Tao Xin, Zhigang Liu, Quan Wang, Lanhong Ma   +4 more
openaire   +3 more sources