Results 141 to 150 of about 4,583,316 (255)
Introduction of LPIN1 as a potential diagnostic and prognostic biomarker for gastric cancer via integrative bioinformatics analysis of a competing endogenous RNA network and experimental validation [PDF]
Objective(s): Identification of effective biomarkers is crucial for the heterogeneous disease of gastric cancer (GC). Recent studies have focused on the role of pseudogenes regulating gene expression through competing endogenous RNA (ceRNA) networks ...
Milad Daneshmand-Parsa, Parvaneh Nikpour
doaj +1 more source
Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu +8 more
wiley +1 more source
Screening of prognostic biomarkers for endometrial carcinoma based on a ceRNA network
Objective This study aims to reveal the regulation network of lncRNAs-miRNAs-mRNA in endometrial carcinoma (EC), to investigate the underlying mechanisms of EC occurrence and progression, to screen prognostic biomarkers.
Zheng, Ming-Jun +8 more
openaire +3 more sources
Creation of the competitive endogenous RNA (ceRNA) regulatory network.
(A) The ceRNA regulatory network included 18 DEmRNAs, 13 DEmiRNAs, and 29 DElncRNAs in PCOS and control group. DEmRNAs, DEmiRNAs, and DElncRNAs are denoted as green triangles, pink circles, and blue diamonds, respectively.
Fan Qu (4763652) +5 more
core +1 more source
Liquid Biopsy: Past, Present, and Future
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu +8 more
wiley +1 more source
Mingjiang Li,1 Bo Yang,1 Xiaoping Li,1 Haixia Ren,2 Liang Zhang,1 Lei Li,1 Wei Li,1 Xuhui Wang,1 Honggang Zhou,3 Weidong Zhang1 1Department of Thoracic Surgery, Tianjin First Central Hospital, Tianjin, People’s Republic of China; 2Department of Pharmacy,
Li M +9 more
doaj
Long non‐coding RNAs (lncRNAs) act as key regulators of economically important traits in livestock through diverse mechanisms including ceRNA networks, epigenetic regulation (X‐inactivation and imprinting) and liquid–liquid phase separation (LLPS).
Keyvan Khani +2 more
wiley +1 more source
Natural Product‐Induced Ferroptosis to Overcome Therapy Resistance in Aggressive Cancers
Natural products trigger ferroptosis through iron overload, glutathione depletion, glutathione peroxidase 4 inhibition, and reactive oxygen species accumulation, selectively targeting aggressive, and drug‐resistant cancers. Polyphenols, alkaloids and terpenoids emerge as promising multi‐target agents to overcome therapy resistance and improve future ...
Giorgio Antoniolli
wiley +1 more source
Chronic renal failure (CRF) is associated with multiple complications, a poor prognosis, and limited therapeutic options. Recent studies have shown that the competitive endogenous RNA (ceRNA) network mediated by long non-coding RNAs (lncRNAs) and ...
Jiayuan LI +4 more
doaj +1 more source

